In today's episode, Dr. Jeremy London, board-certified cardiovascular surgeon, breaks down the most common cholesterol question he gets: how do you actually lower your ApoB? He explains why ApoB predicts cardiovascular risk better than LDL-C, why insulin sensitivity is the through line connecting sugar, saturated fat, fiber, muscle, and body weight, and what to do when you've done everything right and your numbers still won't budge.
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00:00:00 The #1 Cholesterol Question I Get Asked
00:01:00 Why Nobody Knew What ApoB Was 10 Years Ago
00:01:40 LDL-C vs. ApoB: The Truck Analogy
00:03:20 What Is an "Optimal" ApoB? (90 / 80 / 70)
00:05:00 Why Your Doctor Isn't Testing For This
00:06:20 The Two Foundational Buckets
00:07:20 Diet #1: Sugar, Starch & the Insulin Connection
00:11:20 Diet #2: Saturated Fat and the Substitution Trap
00:13:20 Diet #3: Fiber — Not Sexy, But It Works
00:16:20 Is Dietary Cholesterol Actually the Problem?
00:19:20 Exercise #1: Muscle Is Your Biggest Glucose Sink
00:21:40 Exercise #2: Weight Loss & Visceral Fat
00:24:40 What If You Do Everything and Nothing Changes?
00:26:40 Medications Are NOT a Failure
00:29:00 Statins: The Most Demonized Drug in Medicine
00:32:40 Ezetimibe
00:34:00 PCSK9 Inhibitors & the Genetic Evidence
00:36:40 Bempedoic Acid
00:38:00 Why Medication Alone Is Never Enough
00:39:20 Pulling Every Lever
00:40:40 Thank You For Listening!
** The information in this video is not intended nor implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained in this video is for general information purposes only and does not replace a consultation with your own doctor/health professional **
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