The Michael J. Fox Foundation Parkinson's Podcast

The Importance of Sex and Gender Factors in Neurodegenerative Disease Research and Care with Antonella Santuccione Chadha


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Increasing evidence supports the presence of sex and gender differences in neurodegenerative conditions, including Alzheimer's disease and Parkinson's disease. There is a critical need to more closely examine sex and gender differences in all stages of research, therapeutic development, and clinical treatment to enable better outcomes through precision medicine approaches. This episode focuses on the relevance of sex and gender factors in Parkinson's disease and efforts to transform scientific research, policy, and healthcare to identify and address needs based on sex and gender. Our guest Dr. Antonella Santuccione Chadha discusses her work with the Women’s Brain Project, their recent roundtable on enhancing care in Parkinson’s disease, and the organization's goals for the future. Antonella is a medical doctor with experience spanning positions in clinical care, academic research, the Swiss Agency for Therapeutic Products (regulatory), and industry leadership and consultation for large pharmaceutical companies and smaller start-up companies. She is currently Co-Founder and Pro Bono Chief Executive Officer of the Women’s Brain Project, an international non-profit organization studying sex and gender determinants to brain and mental health.

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This podcast episode was part of a limited series created by The Michael J. Fox Foundation in 2023 and 2024 for clinicians and researchers in our audience.  These episodes provide a deeper dive into exciting new scientific research in Parkinson’s disease, as well as innovative tools and valuable resources, through conversations with a variety of experts in the field. We hope you enjoy the conversation.

The Foundation’s landmark research study is exploring the connection between sense of smell and brain disease. People with and without Parkinson's can help by taking a free scratch-and-sniff test. Get yours at mysmelltest.org/request.

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The Michael J. Fox Foundation Parkinson's PodcastBy The Michael J. Fox Foundation for Parkinson’s Research

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