Original Air Date: December 30, 1986

Imagine giving birth and having your joy suddenly turn to anxiety and depression, followed by frightening hallucinations and being committed to a mental hospital, because you are a danger to yourself and to your new baby. Oprah interviews author Carol Dix, Dr. Nana Stotland, and a panel of mothers that had postpartum depression to discuss the causes and treatment of the mental illness. Featured expert Carol Dix passed away in 2021.

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Original Air Date: December 26, 1986

No matter how rough the previous year was, the next can be full of unlimited success, happiness, and total joy. Oprah, a panel of self-help experts and audience members discuss how to process your feelings for a better life. Featured experts Dr. Wayne Dyer passed away in 2015, Shaki Gawain passed away in 2018 and Arnold Patent passed away in 2023.

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Original Air Date: December 24, 1986

They are people who often go unnoticed and unappreciated, but always put others before themselves. Oprah interviews a panel of American heroes to discuss their inspirational good deeds.

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Original Air Date: December 1, 2005

Oprah travels 7,000 miles to see how a modern-day saint helps thousands of young Ethiopian girls and Nate Berkus has a hope-filled tsunami follow-up. Featured Nobel Peace Prize winner Dr. Catherine Hamlin passed away in 2020.

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Original Air Date: November 18, 2005

The Little League tragedy that made headlines. Their boy is dead. Their 13-year-old son swung the bat that killed him. A father faces the teen who killed his family. Plus, more families face the people responsible for their loved ones' deaths.

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Original Air Date: November 16, 2005

After 13 years, Mary Jo breaks her silence about Amy, Joey and nearly dying. Why did she stay with Joey for so long? What does she think of Amy Fisher? It was the national obsession, and now Mary Jo Buttafuoco tells all.

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Original Air Date: November 13, 2006

One woman says she's unlocked the secret language of babies. Then, meet the first real-life bionic woman, and a teen who can see without eyes. And, injured in Iraq, they said she wouldn't survive. Meet the soldier and the doctor who never gave up hope.

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Original Air Date: October 20, 2006

Caring for their sick parents, becoming the head of their household, struggling to raise their younger siblings… Oprah talks with Lisa Ling about children who have taken on the role of parents or caregivers in their families and have had their childhood taken away from them.

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Original Air Date: May 30, 2007

Shot in cold blood and left for dead. If this happened to you, could you love the man who did it? From inside prison, her attacker responds. Then, a woman who barely survived the bombing that struck fear around the world and the decision that saved her. Oprah interviews guests that have suffered horrible acts of violence and have forgiven their attackers.

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Original Air Date: May 4, 2006

Meet the people behind the big ideas that made them millions of dollars, like the creators of Phat Farm, Crayola crayons, Dove Bars and more. They all started small and made it big. Plus, learn about the stay-at-home mom whose chicken recipe won a million dollars.

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