The Peter Attia Drive

In this episode, Dr. Debra Kimless and Steve Goldner share their knowledge on the science, policy, and market evolution of medicinal cannabis. We start with the differences between THC and CBD, how they work in the body, and how they act on the brain. We discuss the many potential benefits of using CBD, THC, hemp in the various forms of administration (smoking, vaping, edibles, oils, etc.) as well as some of the safety issues including the recent uptick in incidents of hospitalization and death linked to vaping. Debra and Steve are both involved with the company, Pure Green—Debra the Chief Medical Officer and Steve the founder and CEO—whose aim is to create the safest, most efficacious form of delivery of cannabis. Their bigger mission is to shift the perception of the cannabis plant, garner acceptance of its medicinal benefits, and ultimately get it descheduled on a federal level so more people can access cannabis for a range of chronic ailments.

We discuss:

• Debra and Steve's background reason for their interest in medical cannabis [7:00];
• The history of medical use of cannabis [11:15];
• How THC, CBD, and other cannabinoids work [16:00];
• Hemp—What it is, special uses, and the 2018 farm bill [22:45];
• The legal status of CBD, Deb and Steve's clinical trial, and how CBD differs from THC [30:15];
• The safety profile of THC [35:00];
• Is marijuana as a gateway drug? [45:30];
• Smoking vs. vaping vs. edibles—Benefits, risks, and mechanistic differences [53:30];
• Can you build up a tolerance to the effects of THC? [1:15:00];
• What do people generally want to get from using marijuana? [1:17:15];
• Cannabinoid synthetics [1:22:30];
• Efficacy of CBD oils as a sleep aid [1:25:00];
• Pure Green Cannabis [1:30:30];
• Anecdotal evidence and managing the hype surrounding cannabis in medical treatment [1:38:45];
• Aspirations for the future of medicinal cannabis, and the legal challenges that await them [1:45:15];
• Descheduling cannabis: A human rights issue [2:04:00] and;
• More.

Learn more: https://peterattiamd.com/ Show notes page for this episode: https://peterattiamd.com/debrakimless-stevegoldner/ Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on Facebook | Twitter | Instagram.

Today's episode of The Qualys is from podcast #10 – Matt Kaeberlein, Ph.D.: rapamycin and dogs — man's best friends? — living longer, healthier lives and turning back the clock on aging and age-related diseases.

The Qualys is a subscriber-exclusive podcast, released Tuesday through Friday, and published exclusively on our private, subscriber-only podcast feed. Qualys is short-hand for "qualifying round," which are typically the fastest laps driven in a race car—done before the race to determine starting position on the grid for race day. The Qualys are short (i.e., "fast"), typically less than ten minutes, and highlight the best questions, topics, and tactics discussed on The Drive.

Occasionally, we will also release an episode on the main podcast feed for non-subscribers, which is what you are listening to now.

Learn more: https://peterattiamd.com/podcast/qualys/

Subscribe to receive access to all episodes of The Qualys (and other exclusive subscriber-only content): https://peterattiamd.com/subscribe/

Connect with Peter on Facebook.com/PeterAttiaMD | Twitter.com/PeterAttiaMD | Instagram.com/PeterAttiaMD

In this special, bonus celebrity AMA episode, Peter answers questions from former Olympians and past guests, Apolo Ohno and Sasha Cohen, on a wide range of subjects including fasting, learning, training for performance versus longevity, and much more. This bonus AMA is available in full to everyone.

• Apolo's questions begin [1:45];
• Why women may have a harder time fasting, and tips for those who are struggling [2:10];
• Is there any place for fasting as part of a nutritional strategy in adolescents? [6:15];
• Tips for learning and retaining large amounts of new information (and the best nutritional approach) [9:15];
• Must read books of 2019 [14:45;
• If you could only keep a few watches for the rest of your life which would they be? [16:45];
• What workout would Peter do inside a hotel room? [22:15];
• What is Peter's ultimate gorge meal? [23:45];
• How do you foresee fasting as a mechanism for performance in athletes? [25:30];
• What is driving Peter to strive for excellence? [33:30];
• Sasha's questions begin [38:40];
• What are you most excited about in the longevity space? [38:45];
• At what point do you see enough data or proof that a new drug, or type of fasting is worth trying it out for yourself? [41:30];
• Is it possible to obsess so much about your health that it becomes a negative stressor? [46:45];
• Which tests are worth doing if you want to be proactive about your health? [48:15];
• Are there any supplements Peter things are beneficial to be taking? [55:15];
• How does Peter's training differ when optimizing for performance versus longevity? [56:30];
• How does taking testosterone and growth hormone affect performance versus longevity? [59:15]; and
• More.

Learn more: https://peterattiamd.com/

Show notes page for this episode:https://peterattiamd.com/celebrityama01 Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on Facebook | Twitter | Instagram.

Today's episode of The Qualys is from podcast #02 – Rhonda Patrick, Ph.D.: the performance and longevity paradox of IGF-1, ketogenic diets and genetics, the health benefits of sauna, NAD+, and more.

The Qualys is a subscriber-exclusive podcast, released Tuesday through Friday, and published exclusively on our private, subscriber-only podcast feed. Qualys is short-hand for "qualifying round," which are typically the fastest laps driven in a race car—done before the race to determine starting position on the grid for race day. The Qualys are short (i.e., "fast"), typically less than ten minutes, and highlight the best questions, topics, and tactics discussed on The Drive.

Occasionally, we will also release an episode on the main podcast feed for non-subscribers, which is what you are listening to now.

Learn more: https://peterattiamd.com/podcast/qualys/

Subscribe to receive access to all episodes of The Qualys (and other exclusive subscriber-only content): https://peterattiamd.com/subscribe/

Connect with Peter on Facebook.com/PeterAttiaMD | Twitter.com/PeterAttiaMD | Instagram.com/PeterAttiaMD

In this episode, Ric Elias, founder of Red Ventures, opens up about the fateful day he knew for certain that he was going to die as a passenger on US Airways Flight 1549. Ric dives deep into how that day impacted his life, greatly changed his perspective, and improved his relationship with his family and the broader community. We also talk about his incredible role as CEO of an enormous company, his remarkable work in philanthropy, and all the wisdom he has acquired in his extraordinary life. We discuss:

• Ric's life leading up to the day of the plane crash [5:30];
• The plane crash—What it's like knowing you're about to die, feelings of regret and sadness [11:15];
• The improbable plane landing in the Hudson River [19:00];
• Emotions after the safe landing (and a story he's never told before) [25:45];
• A powerful story about Captain Sully [29:30];
• Earning his second chance at life, and playing the "infinite game" [38:30];
• Why time is the ultimate currency, and how (and why) to say "no" [46:15];
• Raising kids in an achievement culture, Ric's definition of life success, and what Ric wants to instill in his kids [53:00];
• What Ric believes is actually worth getting upset, and the organizations that are taking steps to help people [1:09:00];
• The core principles of Red Ventures (Ric's company) [1:19:15];
• Ric's tips for developing business acumen and negotiation skills [1:29:30];
• What qualities does Ric look for in people he wants to work with? [1:32:50];
• What is the next big problem that Ric wants to solve? [1:35:30];
• What is the most challenging part of your business today? [1:37:30];
• If Ric could go back and talk to himself in the morning before getting on that plane, what would he say? [1:39:15]; and
• More.

Learn more: https://peterattiamd.com/ Show notes page for this episode: https://peterattiamd.com/ricelias Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on Facebook | Twitter | Instagram.

Today's episode of The Qualys is from podcast #39 – Ted Schaeffer, M.D., Ph.D.: How to catch, treat, and survive prostate cancer.

The Qualys is a subscriber-exclusive podcast, released Tuesday through Friday, and published exclusively on our private, subscriber-only podcast feed. Qualys is short-hand for "qualifying round," which are typically the fastest laps driven in a race car—done before the race to determine starting position on the grid for race day. The Qualys are short (i.e., "fast"), typically less than ten minutes, and highlight the best questions, topics, and tactics discussed on The Drive.

Occasionally, we will also release an episode on the main podcast feed for non-subscribers, which is what you are listening to now.

Learn more: https://peterattiamd.com/podcast/qualys/

Subscribe to receive access to all episodes of The Qualys (and other exclusive subscriber-only content): https://peterattiamd.com/subscribe/

Connect with Peter on Facebook.com/PeterAttiaMD | Twitter.com/PeterAttiaMD | Instagram.com/PeterAttiaMD

In this episode, Sasha Cohen, former US Olympic figure skater, discusses the most challenging things about life as an Olympian—the pressures, the expectations, years of sacrifice, but worst of all a loss of identity post-career resulting in many former Olympians suffering from depression. We begin by talking about everything that led up to her unforgettable moment from the 2006 Olympics, and how she handled herself so beautifully in the face of disaster. Most importantly, we talk about post-skating life when she shares many insights such as the downside of constantly striving for a moment, the hollowness of achievement, and the importance of redefining our definition of success.

We discuss:

• Sasha's mindset going into the 2006 Olympics as the favorite [6:30];
• Figure skating basics, scoring, short program vs. long program, etc. [13:40];
• Sasha's unforgettable performance at the 2006 Olympics [18:10];
• Win, lose, or draw, why many Olympians suffer from a loss of identity [32:30];
• Dealing with the disappointment of "losing the gold" [40:30];
• The tiny window of opportunity for Olympians, and the overwhelming pressure to meet expectations [49:30];
• Sasha's unique childhood, finding figure skating, and channeling her hyperactive personality into becoming an amazing skater [1:01:30];
• The consequences of extreme training at a young age, and trying to control the uncontrollable [1:10:00];
• What is driving extreme athletes and Olympians to be the best? [1:18:30];
• Why many former Olympians and athletes struggle with depression [1:25:00];
• Refining success—How Sasha overcame her own loss of identity [1:32:30];
• What advice would Sasha give her 15-year-old self? [1:40:45];
• Lessons we can learn from watching the rapid downfall of many former Olympians [1:45:00];
• Advice for people who are tying their identity to being "successful" or striving to be "the best" [1:56:00];
• Life lessons Sasha wants to apply to being a mother to her baby boy she is expecting [2:05:00]; and
• More.

Learn more: https://peterattiamd.com/ Show notes page for this episode:https://peterattiamd.com/sashacohen Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on Facebook | Twitter | Instagram.

Today's episode of The Qualys is from podcast #26 – AMA #3: supplements, women's health, patient care, and more.

The Qualys is a subscriber-exclusive podcast, released Tuesday through Friday, and published exclusively on our private, subscriber-only podcast feed. Qualys is short-hand for "qualifying round," which are typically the fastest laps driven in a race car—done before the race to determine starting position on the grid for race day. The Qualys are short (i.e., "fast"), typically less than ten minutes, and highlight the best questions, topics, and tactics discussed on The Drive.

Occasionally, we will also release an episode on the main podcast feed for non-subscribers, which is what you are listening to now.

Learn more: https://peterattiamd.com/podcast/qualys/

Subscribe to receive access to all episodes of The Qualys (and other exclusive subscriber-only content): https://peterattiamd.com/subscribe/

Connect with Peter on Facebook.com/PeterAttiaMD | Twitter.com/PeterAttiaMD | Instagram.com/PeterAttiaMD

In this special episode, Matthew Walker returns for his second AMA episode where he provides his expert insight on numerous sleep-related questions directly from listeners. He answers a wide range of questions from the gene that causes the short sleeping phenotype, to the ideal sleeping position, to the optimal temperature for best sleep, to how fasting affects sleep, plus a full dissertation on sleep apnea, and much, much more. We discuss:

• DEC2—A genetic mutation that produces a short sleeping phenotype [11:00];
• What is the best position to sleep in? [22:45];
• Should you consider a "sleep divorce" with your partner? [27:00];
• The challenge of kids wanting to sleep in bed with their parents [28:45];
• Is there an ideal type of pillow? [32:30];
• Any data on hammock sleeping? Should adults be rocked to sleep like a baby? [34:45];
• The optimal room temperature and body temperature for the best sleep [38:30];
• Do humidifiers help? [50:40];
• How do high altitudes affect sleep? [53:15];
• What is the data on weighted blankets (e.g., the Gravity blanket)? [57:00];
• Caffeine—How much, and in what way, does it affect sleep? [58:15];
• How does sexual activity relate to sleep quality? [1:04:00];
• Should we be sleeping in two phases? First sleep & second sleep? [1:06:30];
• Napping—Is there ideal duration? Should we be napping or not? [1:08:30];
• Advice for new parents dealing with sleep deprivation [1:12:00];
• Understanding your sleep chronotype [1:16:15];
• If you drink too much alcohol in a given night, is there anything you can do to make sure your sleep isn't wrecked? [1:20:45];
• How postmenopausal women can manage their sleep problems with (and without) hormone replacement therapy [1:23:00];
• Could a daily practice of Wim Hof's breathing method help or hinder quality of sleep? [1:29:15];
• Why do some people paradoxically feel more tired the more they sleep? [1:31:15];
• Sleep apnea—How to know if you have it, the different types, the causes, and helpful resources [1:33:15];
• Is there such a thing called "sleep eating"? [1:45:00];
• If Matt was "sleep czar", what changes would he make to society to improve sleep? [1:46:15];
• Catch up sleep: Explaining the difference between retrospective damage and prospective benefit [1:48:45];
• Does poor sleep really speed up the aging process? [1:50:30];
• Is medicated sleep better than no sleep? [1:53:00];
• Does vivid dreaming disrupt the sleep cycle? [1:56:45];
• Is there potential benefit to using "binaural beats" or some type of sound to induce better sleep? [1:57:45];
• How is sleep affected by fasting and time-restricted eating? [1:59:45];
• Is there any evidence that polyphasic sleep (e.g., "Uberman") works? [2:03:30]; and
• More.

Learn more: https://peterattiamd.com/ Show notes page for this episode: peterattiamd.com/matthewwalkerama2/ Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on Facebook | Twitter | Instagram.

Today's episode of The Qualys is from podcast #09 – David Sabatini, M.D., Ph.D.: rapamycin and the discovery of mTOR — the nexus of aging and longevity?.

The Qualys is a subscriber-exclusive podcast, released Tuesday through Friday, and published exclusively on our private, subscriber-only podcast feed. Qualys is short-hand for "qualifying round," which are typically the fastest laps driven in a race car—done before the race to determine starting position on the grid for race day. The Qualys are short (i.e., "fast"), typically less than ten minutes, and highlight the best questions, topics, and tactics discussed on The Drive.

Occasionally, we will also release an episode on the main podcast feed for non-subscribers, which is what you are listening to now.

Learn more: https://peterattiamd.com/podcast/qualys/

Subscribe to receive access to all episodes of The Qualys (and other exclusive subscriber-only content): https://peterattiamd.com/subscribe/

Connect with Peter on Facebook.com/PeterAttiaMD | Twitter.com/PeterAttiaMD | Instagram.com/PeterAttiaMD