Vivaldi. Bach. The Beatles. The Johns Hopkins playlist has been the standard soundtrack in psychedelic trials at Johns Hopkins and therapy rooms around the world for more than 25 years. It also skews toward Classical and Christian music. When Sughra Ahmed, a Muslim, enrolled in a psilocybin study that used this playlist, she didn’t love what she heard. So where did this playlist come from exactly? And what can science tell us about what role music plays in a trip?

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Co-produced by PRX and the UC Berkeley Center for the Science of Psychedelics, Altered States is an award-winning podcast, taking home a 2025 Signal Award for Science and the 2026 Webby Award for Science and Education. To learn more, visit us our website.