This Week in Startups

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Today's show: Jason and Alex cover CoreWeave's filing for a $35 billion IPO after explosive revenue growth. But with 77% of its revenue coming from just two customers, is it built to last? Meanwhile, AVRide is bringing autonomous Hyundai robotaxis to Uber in Dallas, pushing the self-driving revolution forward as Waymo scales to 200,000 weekly rides. And finally, Digg is back! Kevin Rose and Alexis Ohanian are reviving the iconic social news platform, using AI-powered moderation to tackle Reddit's biggest challenge. Tune in as Jason and Alex break it all down!

Timestamps:

(0:00) Episode teaser(1:34) Jason's South by Southwest appearances & All In fan meetups(4:17) Digg relaunch, history, and Kevin Rose's AI strategy(10:05) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(11:43) Jason's involvement with Digg's revival and lessons learned(15:02) Using Reddit for startup communities(20:00) Lemon.io. Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(22:07) Kevin Rose's journey and ketamine therapy(24:18) CoreWeave's public filing, clients, and revenue growth(29:52) Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial set up.(34:22) CoreWeave's potential acquisition and investor IRR(40:45) Using LLMs for financial analysis and political funding discussion(46:19) CoreWeave data centers and AV Ride partnership with Uber(50:18) Challenges in electric bikes and healthcare startups(53:10) Novo Nordisk's direct-to-consumer strategy with Wegovy(57:28) Future of healthcare and Brian Johnson's health regimen(1:05:52) Challenges and excitement in the autonomous vehicle industry

Links from episode:

Check out digg: https://digg.com/

Check out AVRide: https://www.avride.ai/robot

Check out the Mozi app: https://www.mozi.app/

Check out Nerd Crawler: https://www.nerdcrawler.com/

Check out article about Novo Nordisk and Wegovy: https://www.cnbc.com/2025/03/05/novo-nordisk-goes-direct-to-consumer-with-wegovy-what-it-means-for-obesity-rival-eli-lilly.html

Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com

Check out the TWIST500: https://www.twist500.com

Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

Follow Alex:

X: https://x.com/alex

LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm

Follow Jason:

X: https://twitter.com/Jason

LinkedIn: https://www.linkedin.com/in/jasoncalacanis

Thank you to our partners:

(10:05) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(20:00) Lemon.io. Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(29:52) Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial set up.

Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman

Check out Jason's suite of newsletters: https://substack.com/@calacanis

Follow TWiST:

Twitter: https://twitter.com/TWiStartups

YouTube: https://www.youtube.com/thisweekin

Instagram: https://www.instagram.com/thisweekinstartups

TikTok: https://www.tiktok.com/@thisweekinstartups

Substack: https://twistartups.substack.com

Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

In this episode: Jason sits down with Harrison Chase, CEO of LangChain, to explore how AI-powered agents are transforming the way startups operate. They discuss the shift from traditional entry-level roles to AI-driven automation, the importance of human-in-the-loop systems, and the future of AI-powered assistants in business. Harrison shares insights on how companies like Replit, Klarna, and GitLab are leveraging AI agents to streamline operations, plus a look ahead at what's next for AI-driven workflows. Brought to you in partnership with Google Cloud.

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Timestamps:

(0:00) Introduction to Startup Basics series & Importance of AI in startups(2:04) Partnership with Google Cloud & Introducing Harrison Chase from Langchain(4:38) Evolution of entry-level jobs & Examples of AI agents in startups(8:00) Challenges & Future of AI agents in startups(14:24) AI agents in collaborative spaces & Non-developers creating AI agents(18:40) Closing remarks and where to learn more

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Uncover more valuable insights from AI leaders in Google Cloud's 'Future of AI: Perspectives for Startups' report. Discover what 23 AI industry leaders think about the future of AI—and how it impacts your business. Read their perspectives here: https://goo.gle/futureofai

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Check out all of the Startup Basics episodes here: https://thisweekinstartups.com/basics

Check out Google Cloud: https://cloud.google.com/

Check out LangChain: https://www.langchain.com/

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Follow Harrison:

LinkedIn: https://www.linkedin.com/in/harrison-chase-961287118/

X: https://x.com/hwchase17

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Follow Jason:

X: https://twitter.com/Jason

LinkedIn: https://www.linkedin.com/in/jasoncalacanis

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Instagram: https://www.instagram.com/thisweekinstartups

TikTok: https://www.tiktok.com/@thisweekinstartups

Substack: https://twistartups.substack.com

Today's show: Trump just floated the idea of a U.S. Crypto Reserve, suggesting a 10 bips transaction tax and naming unexpected altcoins like XRP, Solana, and Cardano. Jason and Alex break down what this means for crypto markets, regulation, and startups—plus the legal and political fallout. Is this a game-changer or just another pump-and-dump controversy?

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Timestamps:

(0:00) Alex and Jason kick of the show!(1:48) Trump's crypto policy and PR strategy(7:14) Analysis of Trump's proposed US crypto reserve

(10:21) Gusto. Get three months free when you run your first payroll at http://gusto.com/twist(11:32) Predictions on legal challenges to Trump's crypto proposal(12:08) Industry reactions to the crypto tax proposal

(20:27) OpenPhone. Get 20% off your first six months at https://www.openphone.com/twist⁠(22:26) Crypto report around market hours and Eric Trump's tweet(24:13) Predictions on Trump's future crypto policies and inflation impact(27:10) Trump's Truth Social and Crypto Investments dynamics(30:48) LinkedIn Jobs. Post your first job for free at https://www.linkedin.com/twist(31:05) Jason's alternative idea for a crypto tax(36:40) Ramp's funding and fintech sector growth(41:02) Discussion on investment performance and Jason's ETF idea(46:42) Challenges companies face with public offerings and market fairness(50:14) Potential CoreWeave IPO and high CapEx costs(54:39) Founder Hack from Matt Turck(57:12) Exploring hybrid business models

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Links from the episode:

Check out Angel University: https://www.angel.university/Check out the JCal Case Study at Stanford Business: https://www.gsb.stanford.edu/faculty-research/case-studies/jason-calacanis-case-study-creating-resourcesCheck out Arduino: https://www.arduino.cc/Check out Ramp: https://ramp.com/

Check out Coreweave: https://www.coreweave.com/

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Check out the TWIST500: https://www.twist500.com

Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

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Follow Alex:

X: https://x.com/alex

LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm*

Follow Lon:

X: https://x.com/Lons

LinkedIn: https://www.linkedin.com/in/lonharris

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Follow Jason:

X: https://twitter.com/Jason

LinkedIn: https://www.linkedin.com/in/jasoncalacanis

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Thank you to our partners:

(10:21) Gusto. Get three months free when you run your first payroll at http://gusto.com/twist(20:27) OpenPhone. Get 20% off your first six months at https://www.openphone.com/twist⁠(30:48) LinkedIn Jobs. Post your first job for free at https://www.linkedin.com/twist

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Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

*

Check out Jason's suite of newsletters: https://substack.com/@calacanis

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Follow TWiST:

Twitter: https://twitter.com/TWiStartups

YouTube: https://www.youtube.com/thisweekin

Instagram: https://www.instagram.com/thisweekinstartups

TikTok: https://www.tiktok.com/@thisweekinstartups

Substack: https://twistartups.substack.com

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Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

Today's show: Jason and Alex break down the latest head-scratching SEC ruling on meme coins—did they just legalize pump-and-dumps to protect Trump's token? Plus, they dive into why venture debt can destroy startups, the rise of AI-driven companies, and how Tesla is gearing up to challenge Waymo in the self-driving car race. Then, Brandon Brown from GRIN joins the show to talk about scaling to 8-figure revenue, surviving brutal market corrections, and why he's stepping down as CEO after a decade. This one's packed with insights for founders, investors, and anyone watching the future of crypto, startups, and AI unfold.*

Timestamps:

(0:00) Jason and Alex kick off the show!(1:39) Palmer Luckey feud, and supporting Trump in Silicon Valley(9:36) AI's impact on startup growth and job displacement

(10:11) Paddle. Go to https://www.paddle.com/twist to get started with your exclusive listener fee-free period.(12:20) Product market fit and Salesforce productivity(15:01) Howey Test and its application to cryptocurrencies

(20:07) LinkedIn Ads. Get a $100 LinkedIn ad credit at http://www.linkedin.com/thisweekinstartups(26:13) Jason's libertarian views on meme coins

(31:13) Hubspot for Startups. Get up to 75% off plus 3 months of Perplexity AI for free. Go to https://www.hubspot.com/startups(32:16) Meme coin regulation and political implications(37:22) GRIN's Brandon Brown interview and company evolution(46:10) Leadership changes and challenges at GRIN(53:28) Venture debt risks and business cycle preparedness(59:00) Leadership skills and defining reality(1:04:13) Updates on Waymo and autonomous rides(1:09:06) Tesla and the global autonomous vehicle market

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Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com

Check out the TWIST500: https://www.twist500.com

Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

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Check out GRIN: https://grin.co/

Checkout Angel University with Jason Calacanis & Mike Savino: https://www.angel.university/

Check out the Founder Friday City Competition: https://www.founderfridays.tech/city-competition

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Follow Brandon

X: https://x.com/Brandon_Brown

LinkedIn: https://www.linkedin.com/in/brandon-brown-0898731/

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Follow Alex:

X: https://x.com/alex

LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm

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Follow Jason:

X: https://twitter.com/Jason

LinkedIn: https://www.linkedin.com/in/jasoncalacanis

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Thank you to our partners:

(10:11) Paddle. Go to https://www.paddle.com/twist to get started with your exclusive listener fee-free period.(20:07) LinkedIn Ads. Get a $100 LinkedIn ad credit at http://www.linkedin.com/thisweekinstartups(31:13) Hubspot for Startups. Get up to 75% off plus 3 months of Perplexity AI for free. Go to https://www.hubspot.com/startups

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Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

*

Check out Jason's suite of newsletters: https://substack.com/@calacanis

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Follow TWiST:

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Instagram: https://www.instagram.com/thisweekinstartups

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Substack: https://twistartups.substack.com

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Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

Today's show: Jason interviews Rahul Vohra, CEO and founder of Superhuman, and Vlad Tenev, CEO and co-founder of Robinhood. This is a packed episode featuring founder tips, fun stories about how Superhuman and Robinhood got their start and much more!

Timestamps:

(0:00) Episode teaser(2:13) Product market fit and founder journeys(3:25) Jason's investment in Superhuman and market positioning(5:14) AI's role and features in Superhuman(10:25) Lemon.io. Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(14:37) Targeting users and competitive advantages(22:23) Evolution and new features of Superhuman

(20:52) Northwest Registered Agent. Get more privacy, more options, and more done—visit northwestregisteredagent.com/twist today!

(24:37) Tackling spam with Superhuman's AI

(27:05) Custom auto labels and email classification

(29:47) Vapi. Go to Vapi.ai and use code Twist200 to get $200 in credits

(32:03) Superhuman's auto reminders and drafts

(34:14) Vlad Tenev and the origins of Robinhood

(39:31) Product design philosophies of Robinhood and Superhuman

(49:29) Scaling design principles and investment decisions(

52:31) Subjectivity in product design

(55:14) Customer feedback in product development

(1:00:00) Superhuman's subscription model and customer acquisition

(1:05:11) PR strategies and news hijacking

(1:12:06) Investment experiences with Robinhood

(1:13:35) Navigating company valuation fluctuations

(1:15:03) Influences on Vlad Tenev and new Robinhood desktop product

(1:22:02) Company resilience and employee reorganization

(1:25:52) Crypto regulation and startup mentality

(1:30:05) Investment trends among Robinhood users

(1:31:12) Retail benefits for startups and capital raising challenges

(1:34:04) Accreditation for private investing and solutions

Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com

Check out the TWIST500: https://www.twist500.com

Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

Links from this episode:

Check out Superhuman: https://superhuman.com/

Check out Superhuman's blog post that details all of the new features Rahul went over in the demo: https://blog.superhuman.com/the-next-superhuman-ai/.

Check out Robinhood Legend: https://robinhood.com/us/en/legend/

Article "How Superhuman Built an Engine to Find Product Market Fit": https://review.firstround.com/how-superhuman-built-an-engine-to-find-product-market-fit/

Check out Rick Rubin's book: https://www.amazon.ca/Creative-Act-Way-Being/dp/0593652886

Article on Bezos and Washington Post: https://www.newsweek.com/bezos-makes-big-change-washington-post-opinion-focus-endorsed-musk-2036618

Media Bias Chart: https://www.allsides.com/media-bias/media-bias-chart

Check out "Working Backwards" book about Amazon insights: https://www.amazon.ca/Working-Backwards-Insights-Stories-Secrets/dp/1250267595

Check out Rahul's article on acquisition: https://www.linkedin.com/pulse/rip-mailbox-founders-how-stop-worrying-love-being-acquired-vohra/

Follow Rahul:

X: https://x.com/rahulvohra

LinkedIn: https://www.linkedin.com/in/rahulvohra/

Follow Vlad:

X: https://x.com/vladtenev

LinkedIn: https://www.linkedin.com/in/vlad-tenev-7037591b/

Follow Jason:

X: https://twitter.com/Jason

LinkedIn: https://www.linkedin.com/in/jasoncalacanis

Thank you to our partners:

(10:25) Lemon.io. Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist

(20:52) Northwest Registered Agent. Get more privacy, more options, and more done—visit northwestregisteredagent.com/twist today!

(29:47) Vapi. Go to Vapi.ai and use code Twist200 to get $200 in credits

Today's show: Jason and Lon break down the latest trends shaping AI training, the evolving job market, and the shifting landscape of social media. A tribute to Steve Jobs on what would have been his 70th birthday explores his lasting impact, Apple's massive $500 billion AI investment, and the future of US manufacturing. The conversation dives into Outlier's role in AI training data, its effects on journalism, and broader job market implications. Jason also shares insights on autonomous vehicles, Apple's AI strategy, and the latest in crypto—covering meme coins, regulatory battles, and the state of angel investing. Plus, a look at Oscar season and the cultural moments making waves.

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Timestamps:

(0:00) Jason and Lon kick off the show!(2:59) TikTok discussion and Steve Jobs' 70th birthday tribute(4:36) Jason's history with Steve Jobs and impact of blogging(8:56) Jason's interaction with Steve Jobs about podcast monetization(10:13) Squarespace. Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(11:27) Steve Jobs' legacy and Apple's innovation(14:12) Apple's $500 billion investment in AI and TSMC chip manufacturing(20:08) Vanta. Get $1000 off your SOC 2 at https://www.vanta.com/twist(21:18) Geopolitical implications of Apple's US manufacturing investments(24:06) Outlier's role in AI training data and legal risks(27:02) Journalists in AI training and job market implications(30:40) Vapi. Go to https://www.vapi.ai and use code Twist200 to get $200 in credits(32:39) Outlier's AI training recruitment and global reach(34:14) AI's future in various industries(36:53) Experiences with autonomous vehicles and Waymo(37:23) Hot-swappable LLMs and Apple's AI integrations(41:03) Commercial implications of AI deals for Apple(43:08) Public access to podcast docket and meme coins discussion(47:03) Milei's meme coin and libertarian views on crypto(52:15) Crypto trader's tragic incident and dangers of investing on margin(58:19) Jason's gambling habits and future of crypto regulation(1:01:05) Angel investing and Oscar season discussion

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Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com

Check out the TWIST500: https://www.twist500.com

Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

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Follow Lon:

X: https://x.com/Lons

LinkedIn: https://www.linkedin.com/in/lonharris

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Follow Jason:

X: https://twitter.com/Jason

LinkedIn: https://www.linkedin.com/in/jasoncalacanis

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Thank you to our partners:

(10:13) Squarespace. Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(20:08) Vanta. Get $1000 off your SOC 2 at https://www.vanta.com/twist(30:40) Vapi. Go to https://www.vapi.ai and use code Twist200 to get $200 in credits

*

Great TWIST interviews: Will Guidara,Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta,Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

*

Check out Jason's suite of newsletters: https://substack.com/@calacanis

*

Follow TWiST:

Twitter: https://twitter.com/TWiStartups

YouTube: https://www.youtube.com/thisweekin

Instagram: https://www.instagram.com/thisweekinstartups

TikTok: https://www.tiktok.com/@thisweekinstartups

Substack: https://twistartups.substack.com

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Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

This Week in Startups is brought to you by…

Squarespace. Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST

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AdQuick. Visit https://adquick.com/twist and mention TWIST to get $1000 off your first campaign.

Today's show: Jason interviews Bryon Hargis, CEO of Castelion, about the United State's hypersonic technology gap with China, how we're catching up and what it will take to win the hypersonic missile race. Alex interviews Jager McConnell, CEO of Crunchbase, about their newly released, scary accurate, AI powered predictive models.

Timestamps:

(0:00) Episode teaser(1:14) Introduction of Byron Hargis and Castellion's mission(2:20) Significance of hypersonic munitions(5:55) Impact and challenges of hypersonic systems in defense(7:16) Castellion's development and cost of hypersonic weapons(9:39) Squarespace. Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(12:28) Shift in defense contracting and venture backing(18:25) Sales strategies and founder insights in defense startups(19:38) LinkedIn Jobs. Post your first job for free at https://www.linkedin.com/twist(21:10) China's manufacturing capabilities and defense paradigm shifts(24:37) Role of automation and robots in manufacturing(28:58) AdQuick. Visit https://adquick.com/twist and mention TWIST to get $1000 off your first campaign.(31:37) Crunchbase's transition to predictive insights(38:01) Crunchbase's technology stack and AI models(41:36) Financial implications of AI-first model for Crunchbase(48:43) AI integration challenges and financial performance(52:50) AI-driven predictions and their accuracy(54:24) Future prospects for Crunchbase: Acquisition vs. IPO(55:22) Upcoming guests: Vlad from Robinhood and Raul from Superhuman

Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com

Check out the TWIST500: https://www.twist500.com

Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

Checkout Castelion:

X: https://x.com/CastelionCorp

Website: castelion.com

Checkout Crunchbase:

X: https://x.com/crunchbase

Website: https://www.crunchbase.com/

Follow Bryon:

X: https://x.com/hargsb

LinkedIn: https://www.linkedin.com/in/cbh/

Follow Jager:

X: https://x.com/jagermcconnell

LinkedIn: https://www.linkedin.com/in/jager/

Follow Alex:

X: https://x.com/alex

LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm

Follow Jason:

X: https://twitter.com/Jason

LinkedIn: https://www.linkedin.com/in/jasoncalacanis

Thank you to our partners:

(9:39) Squarespace. Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(19:38) LinkedIn Jobs. Post your first job for free at https://www.linkedin.com/twist(28:58) AdQuick. Visit https://adquick.com/twist and mention TWIST to get $1000 off your first campaign.

Great TWIST interviews: Will Guidara,Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta,Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

Check out Jason's suite of newsletters: https://substack.com/@calacanis

Follow TWiST:

Twitter: https://twitter.com/TWiStartups

YouTube: https://www.youtube.com/thisweekin

Instagram: https://www.instagram.com/thisweekinstartups

TikTok: https://www.tiktok.com/@thisweekinstartups

Substack: https://twistartups.substack.com

Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

This Week in Startups is brought to you by…

Gusto. Get three months free when you run your first payroll at http://gusto.com/twist

*Gusto pricing shown in ad is based on pricing prior to March 2025

Lemon.io. Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist

Atlassian. Head to https://www.atlassian.com/software/startups to see if you qualify for 50 free seats for 12 months.

Today's show: Jason and Lon Harris cover Nikola's Chapter 11 and how founders can avoid the same mistake, Superhuman AI's new features, Mira Murati's Thinking Machines and where Sam Altman went wrong holding onto top talent, plus much more!

Timestamps:

(0:00) Episode teaser(1:26) Introduction to startup news and trends(2:47) Bill Ackman's J trade and Herbalife controversy(5:24) Comparing trading strategies: Jason vs. Pelosi(9:49) Gusto. Get three months free when you run your first payroll at http://gusto.com/twist(11:29) HP's acquisition of Humane and its significance(13:52) Challenges facing the AI industry(20:30) Lemon.io. Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(21:47) OpenAI veterans launch a new venture(28:09) Chamath's venture into high stakes poker(29:35) Atlassian. Head to https://www.atlassian.com/software/startups to see if you qualify for 50 free seats for 12 months.(36:37) Nikola's Chapter 11 filing and securities fraud(48:10) The upside of failing as a founder in the U.S.(50:24) Superhuman introduces AI-powered email features(51:58) Preview of upcoming guests on the podcast(53:03) Key characteristics of successful founders(56:21) Play-along: Guess the fake startup(1:04:12) Movie trilogy rankings: Superman, Star Wars, Terminator

Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com

Check out the TWIST500: https://www.twist500.com

Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

Check out these past Guess The Fake Startups segments:

https://www.youtube.com/watch?v=iKP2iiF1oYI

https://www.youtube.com/watch?v=rhnOXuGnh14

https://www.youtube.com/watch?v=ueazpyGOgcc

Follow Lon:

X: https://x.com/alex

Follow Jason:

X: https://twitter.com/Jason

LinkedIn: https://www.linkedin.com/in/jasoncalacanis

Thank you to our partners:

(9:49) Gusto. Get three months free when you run your first payroll at http://gusto.com/twist

*Gusto pricing shown in ad is based on pricing prior to March 2025

(20:30) Lemon.io. Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(

29:35) Atlassian. Head to https://www.atlassian.com/software/startups to see if you qualify for 50 free seats for 12 months.

Great TWIST interviews: Will Guidara,Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta,Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

Check out Jason's suite of newsletters: https://substack.com/@calacanis

Follow TWiST:

Twitter: https://twitter.com/TWiStartups

YouTube: https://www.youtube.com/thisweekin

Instagram: https://www.instagram.com/thisweekinstartups

TikTok: https://www.tiktok.com/@thisweekinstartups

Substack: https://twistartups.substack.com

Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

In today's episode: Jason and Alex break down one of the craziest crypto stories yet—a $100M meme coin meltdown, insider trading, and Argentina's president caught in the middle. Coffeezilla joins the show to explain how meme coins are rigged, why Dave Portnoy got a $5M refund while everyone else got wrecked, and what really went down with the Libra token. Plus, we debate if crypto can be fixed or if the grift is too far gone.

Timestamps:

(0:00) Jason and Alex kick off the show.(2:17) Libra fiasco, crypto scams, and influencer involvement(4:42) The impact of meme coins on politics and ethical considerations(8:02) Trump's involvement in meme coins(10:10) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(11:30) The Libra coin scandal and its broader implications(18:39) Coffeezilla interview clip with Hayden Davis(20:20) Netsuite. Download the CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twist(21:46) Introduction to Pump.fun and discussion on token launching risks(23:21) Coffeezilla joins Alex and Jason!(24:10) Discussion on Argentinian president and Tech Forum Argentina(27:29) Examination of Hayden Davis and token manipulation(29:29) Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial setup.(31:02) Analysis of the broken crypto system and regulatory issues(35:40) Intentional fraud, regulation, and meme coins in politics(41:21) Potential solutions and regulatory controls under new administration(50:23) Concerns and proposed framework for crypto regulation(54:52) Importance of regulation and combating crypto fraud(58:18) Coffeezilla's perspective on meme coins and future regulations(1:01:22) Advice to potential crypto investors and FTC news implications(1:02:08) Impact of regulation on American innovation and tech giants' growth(1:05:03) Current administration's stance on business combinations(1:06:10) Arguments against large companies acquiring competitors(1:07:23) Risks and potential benefits of hypothetical acquisitions(1:08:29) Debate on market competition dynamics

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Follow Coffeezilla:

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Thank you to our partners:

(10:10) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!

(20:20) Netsuite. Download the CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twist

(29:29) Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial setup.*

Great TWIST interviews: Will Guidara,Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta,Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

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Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

Today's show: IPO shakeups, big AI moves, and essential founder hacks—this episode covers it all. Jason breaks down Robinhood's 6X stock surge and his strategy for $HOOD, plus the latest on tech IPOs as Turo pulls out and SailPoint surges. We dive into AI's open-source battle, with X.ai chasing a $10B raise and DeepSeek challenging Hugging Face. And for founders, Jason shares the startup golden rule you should break for success—plus, a brand-new startup idea he's willing to fund right now.

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Timestamps:

(0:00) Jason and Alex kick off the show.(1:51) The 'new' news cycle(2:17) Calming down during chaotic times(4:29) IPO updates: Turo and SailPoint, private equity, public markets, and M&A(9:37) Rental car business & sharing economy job creation

(9:53) Squarespace. Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(12:21) Robinhood's financial performance & fintech resurgence(18:08) NVIDIA's investment in WeRide & self-driving technology(20:02) Paddle. Go to https://www.paddle.com/twist to get started with your exclusive listener fee-free period.

(21:28) Cooking, convenience, DoorDash, Uber, CloudKitchens & startup opportunities(25:45) Smart IoT devices & revisiting the mobile convenience stores idea(29:59) Lemon.io . Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(33:12) XAI's potential funding & AI's impact on consumer behavior(40:49) Revisiting failed startup ideas & founder hacks(47:18) Customer advisory councils: size, incentives, and roles(52:09) Humanoid robots & market competition in the next decade(58:51) OpenAI model selection & user experience(1:00:56) Founder University pitches compilation(1:13:56) Audience question: Addressing criticism on Trump and Elon Musk(1:17:26) Discussion on Palantir, bias, state of journalism, and investigative reporting

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LinkedIn: https://www.linkedin.com/in/jasoncalacanis

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Thank you to our partners:

(9:53) Squarespace. Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(20:02) Paddle. Go to https://www.paddle.com/twist to get started with your exclusive listener fee-free period.

(29:59) Lemon.io . Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist*

Great TWIST interviews: Will Guidara,Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta,Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

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Check out Jason's suite of newsletters: https://substack.com/@calacanis

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Substack: https://twistartups.substack.com

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Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916