This Week in Startups

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Today's show: Jason and Alex cover…TBD

Timestamps:

(0:00) Episode Teaser(1:16) Welcome Alex Wilhelm & Sam Lessin; Slow Ventures Creator Fund(3:49) Significance of the $60M creator-focused fund(5:47) Community-building and product development strategy(7:02) Mr. Beast's success as a case study(9:41) Vanta. Get $1000 off your SOC 2 athttps://www.vanta.com/twist(11:17) Financial structures and strategies in creator investments(14:14) Addressing challenges in creator-focused investing(19:46) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visitnorthwestregisteredagent.com/twist today!(22:24) Startups optimizing operations in challenging climates(24:50) Transition to fusion energy and Helion's technology(27:46) Helion's fusion technology and CEO David Kirtley(29:16) Commercial fusion power timeline(29:43) LinkedIn Ads. Get a $100 LinkedIn ad credit athttp://www.linkedin.com/thisweekinstartups(32:12) Fusion energy's market potential and agreements(33:39) Comparing fusion to other energy sources(36:10) Safety and environmental considerations for fusion(43:00) Helion's upcoming milestones and team expansion(44:00) Lon Harris on AI, copyright, and fair use(47:00) Exploring fair use and IP infringement in AI(53:00) Market impact and licensing for AI technologies(56:00) Financial implications for AI and copyright(58:00) Distinguishing personal vs. commercial use of copyrighted material

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LinkedIn:⁠https://www.linkedin.com/in/alexwilhelm

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X:https://x.com/Lons

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X:https://twitter.com/Jason

LinkedIn:https://www.linkedin.com/in/jasoncalacanis

Thank you to our partners:

(9:41) Vanta. Get $1000 off your SOC 2 athttps://www.vanta.com/twist(19:46) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visitnorthwestregisteredagent.com/twist today!(29:43) LinkedIn Ads. Get a $100 LinkedIn ad credit athttp://www.linkedin.com/thisweekinstartups

Great TWIST interviews:Will Guidara,Eoghan McCabe,Steve Huffman,Brian Chesky,Bob Moesta,Aaron Levie,Sophia Amoruso,Reid Hoffman,Frank Slootman,Billy McFarland

Check out Jason's suite of newsletters:https://substack.com/@calacanis

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Subscribe to the Founder University Podcast:https://www.youtube.com/@founderuniversity1916

Today on This Week in Startups: Lon Harris is back, and we're diving into all things Super Bowl—especially the tech takeover in this year's commercials. We break down the biggest ad moments, from Squarespace to Uber Eats, Instacart, and even Harrison Ford's Jeep spot. Plus, we dig into Google Trends after the ChatGPT ad, the unexpected appeal ofThe Banshees of Inisherin, and Matthew McConaughey's latest move with Salesforce. That's not all—France is making bold AI moves, OpenAI is getting into chip development, and we've got aFounder Fridays competition coming up!

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Timestamps:

(0:00) Jason, Alex and Lon "kick off" the show!(5:09) Breakout Super Bowl commercials(9:23) Rocket's Super Bowl ad and its impact

(10:21)Lemon.io. Get 15% off your first 4 weeks of developer time athttps://Lemon.io/twist(13:00) High-risk hobbies of the rich and famous(15:23) We all loved the new Squarespace ad and its effectiveness(19:07) The appeal of "The Banshees of Inisherin" and ChatGPT Super Bowl ad(20:17) OpenPhone. Get 20% off your first six months athttps://www.openphone.com/twist

(21:34) Google Trends analysis of ChatGPT ad impact(22:19) A look at Kendrick Lamar's Super Bowll half-time show and his popularity(24:15) Rating the ChatGPT Super Bowl ad(31:01) Coda. Empower your startup with Coda's Team plan for free—get 6 months athttps://www.Coda.io/twist(32:42) Uber Eats and Instacart Super Bowl ads & Harrison Ford's Jeep commercial(39:49) Matthew McConaughey's role with Salesforce and A-list actors in 2025(44:14) France's AI investment and strategy(47:10) AI in customer service and SaaS pricing(52:34) IT unemployment and AI's impact on tech support(56:45) Upcoming earnings reports from key tech companies(1:02:12) OpenAI's custom chip development with TSMC(1:02:35) Founder Fridays: A new initiative for founders and competition format*

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Thank you to our partners:

(10:21)Lemon.io. Get 15% off your first 4 weeks of developer time athttps://Lemon.io/twist(20:17) OpenPhone. Get 20% off your first six months athttps://www.openphone.com/twist(30:31)Coda. Empower your startup with Coda's Team plan for free—get 6 months athttps://www.Coda.io/twist*

Great TWIST interviews:Will Guidara,Eoghan McCabe,Steve Huffman,Brian Chesky,Bob Moesta,Aaron Levie,Sophia Amoruso,Reid Hoffman,Frank Slootman,Billy McFarland

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This Week in Startups is brought to you by…

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Today's show: Jason and Alex discuss the carried interest tax loophole being in Trump's crosshairs, a great interview with Orbit Fab and their plans for the industrialization of space, Deel's $300M secondary and much more!

Timestamps:

(0:00) Episode Teaser(1:30) Introduction and welcome(2:40) AI startups reaching revenue milestones(9:00) Impact of carried interest tax changes

(10:01) Squarespace. Use offer code TWIST to save 10% off your first purchase of a website or domain athttps://www.Squarespace.com/TWIST

(11:25) Would ending the carried interest tax loophole hurt startup investing?

(19:17) Atlassian. Head tohttps://www.atlassian.com/software/startups to see if you qualify for 50 free seats for 12 months.(21:18) Introduction of OrbitFab's CEO, Daniel Faber(22:24) OrbitFab's market position, fuel standards, and customer adoption(27:14) Financial and logistical aspects of satellite refueling

(29:27) AdQuick. Visithttps://adquick.com/twist and mention TWIST to get $1000 off your first campaign.(31:03) Technical challenges in space operations and future applications(34:16) Raising capital and company growth in space startups(38:58) Community updates and secondary transactions in the market(49:32) CapBase acquisition by Deal(50:37) UAE-France data center collaboration and energy strategy(54:34) European AI and nuclear advancements(57:14) US tech employment trends and Meta's layoffs(1:00:51) Opportunities for founders and startup support resources

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Thank you to our partners:

(10:01) Squarespace. Use offer code TWIST to save 10% off your first purchase of a website or domain athttps://www.Squarespace.com/TWIST(19:17) Atlassian. Head tohttps://www.atlassian.com/software/startups to see if you qualify for 50 free seats for 12 months.(29:27) AdQuick. Visithttps://adquick.com/twist and mention TWIST to get $1000 off your first campaign.

Great TWIST interviews:Will Guidara,Eoghan McCabe,Steve Huffman,Brian Chesky,Bob Moesta,Aaron Levie,Sophia Amoruso,Reid Hoffman,Frank Slootman,Billy McFarland

Check out Jason's suite of newsletters:https://substack.com/@calacanis

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Subscribe to the Founder University Podcast:https://www.youtube.com/@founderuniversity1916

This Week in Startups is brought to you by…

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Today's show: Jason and Alex cover Palantir's surge (is it all hype?), Temo and Shein and the de minimise loop hole, Uber's earnings and the future of self-driving technology and much more!

Timestamps:

(0:00) Episode Teaser(1:38) New studio space and remote work productivity challenges(4:02) "Severance" vs. "Landman" - TV shows comparison(7:07) Palantir's valuation, financial performance, and stock analysis(9:49) Gusto. Get three months free when you run your first payroll at http://gusto.com/twist

(11:27) Alex Karp talks up Palantir to investors(14:36) Price-sales ratio: Palantir vs. Nvidia and founder advice(19:33) Oracle. TWiST listeners can try OCI and save up to 50% on your cloud bill at ⁠⁠https://w⁠⁠⁠⁠ww.oracle.com/twist⁠⁠⁠(21:46) Temu, Shein, and the de minimis loophole in trade(30:06) Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial set up.(31:34) Uber's earnings, market performance, and self-driving technology future(38:33) Waymo's growth and the commodification of self-driving tech(44:11) Market dominance, platform switching, and competition mental models(47:18) Kalshi, Robinhood, prediction markets, and regulatory challenges(52:17) BYD's self-parking technology and the future of self-driving cars(56:43) Final thoughts and request for startup growth data

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Thank you to our partners:

(9:49) Gusto. Get three months free when you run your first payroll at http://gusto.com/twist

*Gusto pricing shown in ad is based on pricing prior to March 2025(19:33) Oracle. TWiST listeners can try OCI and save up to 50% on your cloud bill at ⁠⁠https://w⁠⁠⁠⁠ww.oracle.com/twist⁠⁠⁠(30:06) Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial set up.

Great TWIST interviews: Will Guidara,Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta,Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

Check out Jason's suite of newsletters: https://substack.com/@calacanis

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Substack: https://twistartups.substack.com

Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

OpenAI dropped Deep Research—hilariously, the exact same name as Google's existing tool. Jason and Alex dive into the AI arms race, break down Lovable.dev's insane growth to $10M ARR in weeks, and test whether AI can really replace software engineers. Plus, they analyze Trump's latest tariff chaos and what it means for startups, global trade, and the economy.

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Timestamps:

(0:00) Jason and Alex kick off the show.

(1:09) Jason's talk and case study at Stanford (2:38) Managing the chaotic news cycle (5:22) NBA trade insights: Luka Doncic and Anthony Davis (7:15) Lovable startup's rapid growth (9:44) Lemon.io. Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist (11:02) Lovable's AI demo and European startup landscape (15:20) Lovable's target market and pricing strategy (19:48) PrizePicks. Run your game. Download the app today and use code TWIST to get $50 instantly after you play your first $5 lineup! Go to: https://prizepicks.onelink.me/LME0/TWIST

(21:39) Custom software development's future with AI (23:17) Launching and designing AI-powered apps (27:07) US sovereign wealth funds and crypto regulation (28:56) LinkedIn Ads. Get a $100 LinkedIn ad credit at http://www.linkedin.com/thisweekinstartups (33:42) Creative tax and debt reduction strategies (41:34) Defense spending and OpenAI's new product (46:51) OpenAI's market impact and ethical considerations (53:02) AI's role in content creation and job market (58:13) Venture capital trends and startup ecosystem (1:01:19) DeepSeek's popularity and security concerns (1:03:28) Tariffs, economic impact, and supply chain importance *

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Check out:

Standford Case Study on Jason: https://www.gsb.stanford.edu/faculty-research/case-studies/jason-calacanis-case-study-creating-resources

OpenAI's Deep Research: https://openai.com/index/introducing-deep-research/

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Follow Anton

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X: https://x.com/lovable_dev

Website: www.lovable.dev

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LinkedIn: https://www.linkedin.com/in/jasoncalacanis

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Thank you to our partners:

(0:00) Lemon.io. Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist (0:00) PrizePicks. Run your game. Download the app today and use code TWIST to get $50 instantly after you play your first $5 lineup! Go to: https://prizepicks.onelink.me/LME0/TWIST (0:00) LinkedIn Ads. Get a $100 LinkedIn ad credit at http://www.linkedin.com/thisweekinstartups *

Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

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Check out Jason's suite of newsletters: https://substack.com/@calacanis

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Today's show: The AI revolution is about to hit your household—Jason and Alex break down how general-purpose robots, AI-powered chicken coops, and voice clones are redefining daily life and work. They dig into OpenAI's sky-high valuation, the surprising rise of DeepSeek's R1 model, and why the AI cost curve is dropping at an insane pace. Plus, the latest on AI hardware, antitrust battles, and why the "No Buy 2025" trend could change how we think about consumer tech.

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Timestamps:

(0:00) Jason and Alex kick off the show. (3:10) Episode topics overview and fan participation (5:48) Meta's Ray-Ban smart glasses discussion (9:27) Paddle. Go to https://www.paddle.com/twist to get started with your exclusive listener fee-free period. (11:05) 11 Labs' Series C funding and voice cloning technology (18:09) Automation's impact on jobs and ethical considerations (20:05) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit ⁠https://www.northwestregisteredagent.com/twist today.

(21:22) Market trends towards sustainability and AI in smart chicken coops (27:04) Y Combinator's AI startup focus and investment considerations (29:47) Scalable Path. Get 20% off your first month at https://www.scalablepath.com/twist (31:42) AI in compliance, auditing, and personal staff replacement (35:06) AI development tools, hardware investments, and data trust issues (39:29) AI company valuations, OpenAI's revenue, and AI commoditization (51:04) AI ethics, SoftBank's strategy, and audience questions on AI hardware (59:27) Government AI funding, DOJ suit, and tech industry commoditization (1:09:21) AI advancements, consumer electronics costs, and computing hardware trends (1:12:08) Closing thoughts on technology's impact on life and teaser for next week

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LinkedIn: https://www.linkedin.com/in/jasoncalacanis

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Thank you to our partners: (9:27) Paddle. Go to https://www.paddle.com/twist to get started with your exclusive listener fee-free period. (20:05) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://www.northwestregisteredagent.com/twist today. (29:47) Scalable Path. Get 20% off your first month at https://www.scalablepath.com/twist *

Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

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Check out Jason's suite of newsletters: https://substack.com/@calacanis

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This Week in Startups is brought to you by…

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Today's show: Jason and Alex cover Jason's unique sauna experience, leading them to discuss the value of niche communities and supporting small startups, spotlighting Boom Supersonic's achievements and Starlink's aviation collaborations. Financial updates include the Federal Reserve's actions and Trump's public opinion. They analyze the impact of CapEx on tech giants and Meta's AR/VR success. The DeepSeek controversy, OpenAI's intellectual property issues, and AI race risks and opportunities are explored. Jason and Alex conclude with insights on building startups and modern tools for entrepreneurs.

Timestamps:

(0:00) Episode Teaser (1:39) Introduction to the podcast; Jason's sauna experience; GoPolar app (3:41) Niche communities; encouraging small startup projects (10:11) Vanta. Get $1000 off your SOC 2 at https://www.vanta.com/twist

(13:48) Boom Supersonic's achievements and flight details (18:30) Starlink's role in aviation; Apple collaboration; Helium project

(20:47) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit ⁠https://www.northwestregisteredagent.com/twist⁠ today. (24:11) Financial updates; Federal Reserve; Trump's public opinion

(30:14) Scalable Path. Get 20% off your first month at https://www.scalablepath.com/twist (31:57) Federal spending; debt strategies; upcoming tech earnings (37:18) Impact of CapEx on tech giants; Meta's AR/VR success (42:26) DeepSeek controversy; OpenAI's response and IP issues (50:13) AI race risks and opportunities; OpenAI's market position (57:13) Building startups; Founder University; modern tools for startups (1:02:15) Closing remarks; upcoming episodes

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Check out:

Boom Supersonic: https://boomsupersonic.com/

GoPolar App: https://www.gopolar.app/

Follow Alex:

X: https://x.com/alex

LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm

Follow Jason:

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LinkedIn: https://www.linkedin.com/in/jasoncalacanis

Thank you to our partners:

(10:11) Vanta. Get $1000 off your SOC 2 at https://www.vanta.com/twist (20:47) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit ⁠https://www.northwestregisteredagent.com/twist today.

(30:14) Scalable Path. Get 20% off your first month at https://www.scalablepath.com/twist

Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

Check out Jason's suite of newsletters: https://substack.com/@calacanis

Follow TWiST:

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Substack: https://twistartups.substack.com

Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

Today's show: A $6M open-source AI model from China, DeepSeek, sends shockwaves through Wall Street, wiping billions off NVIDIA's market cap and forcing a rethink on AI infrastructure spending. We explore the 25% surge in startup shutdowns, the lessons from leaner teams, and why some companies just couldn't make the runway. Plus, SailPoint returns to the public markets saddled with $1.6B in debt—what does this say about private equity's "buy, fix, and flip" strategy? Don't miss this deep dive into the latest tech and startup news!

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Timestamps:

(0:00) Jason and Alex kick off the show. (1:58) DeepSeek's market impact and Project Stargate (4:18) Innovation, H100 GPUs, and open-source AI models (8:41) Jevons paradox, Pat Gelsinger's analogy, and AI efficiency

(10:03) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://www.northwestregisteredagent.com/twist today. (13:25) AI's benefits for startups and privacy concerns (19:32) Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST (19:51) AI optimization vs. hardware consumption

(22:20) OpenAI's revenue, valuation, and NVIDIA's market value (30:13) LinkedIn Jobs. Post your first job for free at https://www.linkedin.com/twist (33:21) Unified AI digital assistants and DeepSeq's new model (35:01) AI's role in venture capital and team size reduction (41:04) China's influence and DeepSeek's market impact (43:22) Startup shutdowns and potential for increased M&A activity (53:02) Nvidia's historical analysis, risks of leverage, and SailPoint's IPO

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Follow Alex:

X: https://x.com/alex

LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm

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Follow Jason:

X: https://twitter.com/Jason

LinkedIn: https://www.linkedin.com/in/jasoncalacanis

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Thank you to our partners:

(10:03) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://www.northwestregisteredagent.com/twist today. (19:32) Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST (30:13) LinkedIn Jobs. Post your first job for free at https://www.linkedin.com/twist *

Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

*

Check out Jason's suite of newsletters: https://substack.com/@calacanis

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Follow TWiST:

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Today's show: Jason and Alex cover Twilio's team size compression, DeepSeek's scary good AI for only $6M and the GameOn fraud saga that sounds too crazy to be true.

Timestamps:

(0:00) Alex and Jason kick off the show (6:27) Rundown of potential topics (7:10) Twilio's team size strategy and AI's impact on workforce

(9:40) Fitbod. Get 25% off your Fitbod subscription or try out the app for FREE when you sign up: fitbod.me/TWIST (14:52) Entrepreneurship in the AI era and automation concerns

(19:30) Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST (22:49) Meta's investment in data centers and surplus compute power

(26:36) Technology's potential to solve humanity's problems (30:12) Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial set up. (32:01) Empathy for workers displaced by automation (34:11) DeepSeq's role in reducing AI industry costs (37:27) Game On startup fraud case and due diligence in startups (53:13) Venture capital's role in startup oversight (55:36) OpenAI's Operator announcement and AI autonomy risks

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Thank you to our partners:

(9:40) Fitbod. Get 25% off your Fitbod subscription or try out the app for FREE when you sign up: fitbod.me/TWIST (19:30) Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST (30:12) Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial set up.

Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

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This Week in Startups is brought to you by…

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Today's show: Alex covers The Stargate Project, other hot news items, and two great interviews. Created By Humans' Co-founder Trip Adler talks about the future of copyrights and AI. Gene Berdichevsky, Co-founder and CEO of Sila, discusses the future of batteries and our clean energy future.

Timestamps:

(0:00) Alex kicks off the show.(1:22) Introduction to Mistral's IPO, Anthropic's funding, and Project Stargate(6:01) Market reactions and AI funding landscape(10:19) Gusto. Get three months free when you run your first payroll at http://gusto.com/twist(11:35) Tripp Adler discusses AI in literature and Created by Humans(16:20) Authors' concerns and AI companies' reactions(19:42) Netsuite. Download the CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twist(20:58) Tripp Adler on AI, copyright, and the future of authorship(27:47) Human-created content symbol and synthetic vs. human data

(29:52) Atlassian. Head to Atlassian.com/Startups/TWiST to see if you qualify for 50 free seats for 12 months.(34:08) Gene Berdichevsky on Sila's battery technology and Titan Silicon anodes(41:29) Battery tech's role in industry transformation and consumer devices(48:25) The impact on renewable energy and grid storage(53:02) Hard tech challenges, fundraising, and IPO considerations(56:38) Netflix's quarterly earnings and tech market forecasts

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Check out:

Created by Humans:

Website: https://www.createdbyhumans.ai/

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X: https://x.com/tripadler

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Follow Alex:

X: https://x.com/alex

LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm

Follow Jason:

X: https://twitter.com/Jason

LinkedIn: https://www.linkedin.com/in/jasoncalacanis

Thank you to our partners:

(10:19) Gusto. Get three months free when you run your first payroll at http://gusto.com/twist

*Gusto pricing shown in ad is based on pricing prior to March 2025(19:42) Netsuite. Download the CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twist(29:52) Atlassian. Head to Atlassian.com/Startups/TWiST to see if you qualify for 50 free seats for 12 months.

Great TWIST interviews: Will Guidara,Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta,Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

Check out Jason's suite of newsletters: https://substack.com/@calacanis

Follow TWiST:

Twitter: https://twitter.com/TWiStartups

YouTube: https://www.youtube.com/thisweekin

Instagram: https://www.instagram.com/thisweekinstartups

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Substack: https://twistartups.substack.com

Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916