This Week in Startups

This Week in Startups

By Jason CalacanisTechnology
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This Week in Startups episodes

  • Why F1 Teams are Replacing Wind Tunnels with Smart Tape | E2305

    This Week In Startups is made possible by:

    Plaud - https://Plaud.ai/twistSentry - https://sentry.io/twistNorthwest Registered Agent-https://northwestregisteredagent.com/twistDigitalOcean - https://do.co/twist


    Today's show:

    F1 teams spend up to a third of their budgets on aerodynamics, often utilizing wind tunnels to simulate what happens on the track.

    But Lyall Davenport of SKN Systems created a sensor-embedded tape that sticks directly to race cars as they drive around the real world, generating 420M data points per hour. And it comes in at roughly 95% less cost than running a full simulator.

    Hear about how Lyall's background in racing helped him develop the concept, plans to expand from motorsports to drones and defense, and his experiences going through Jason's various programs.

    PLUS OpenAI's new models are so good, you can't use them. Why Apple's Vision Pro chief defected to OpenAI (and why their laptops and devices are getting more expensive). A look at the world's most annoying data center in Sterling, Virginia. And Jason remembers iconic and influential tech journalist Om Malik.


    Guest:


    Lyall Davenport: https://x.com/Lyalldavenport

    SKN Systems: https://www.skn.systems/


    Timestamps:

    0:00 How SKN uses tape to generate aerodynamic data

    4:04 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off!

    6:17 How SKN uses tape to generate aerodynamic data

    9:55 Sentry - Your team should be focused on shipping features — not chasing down bugs. New users can get $240 in free credits when they go to https://sentry.io/twist and use the code TWIST

    17:20 F1 teams are worth HOW MUCH?

    19:42 Northwest Registered Agent: Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity — Learn more at https://northwestregisteredagent.com/twist

    20:35 Future markets beyond motorsports

    30:03 DigitalOcean - Want to see what building on a true AI-native platform looks like? Head to https://do.co/twist to start building on DigitalOcean's AI-Native Cloud today — and cut your AI workload costs by up to 50%.

    32:45 GPT-5.6 is banned for now

    43:46 Vision Pro chief makes for the exit

    51:24 Apple raises their prices

    56:05 The data center you're allowed to hate

    1:06:04 Zuck's new prediction market app

    1:08:42 RIP Om Malik (1966-2026)

    1:19:50 Streaming and camera recommendations

    1:28:06 All about eFoiling


    Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com

    Check out the TWIST500: https://www.twist500.com

    Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

    Follow Lon:

    X: https://x.com/lons

    LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm

    Follow Jason:

    X: https://twitter.com/Jason

    LinkedIn: https://www.linkedin.com/in/jasoncalacanis


    Check out all our partner offers: https://partners.launch.co/

    Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

    Check out Jason's suite of newsletters: https://substack.com/@calacanis

    Follow TWiST:

    Twitter: https://twitter.com/TWiStartups

    YouTube: https://www.youtube.com/thisweekin

    Instagram: https://www.instagram.com/thisweekinstartups

    TikTok: https://www.tiktok.com/@thisweekinstartups

    Substack: https://twistartups.substack.com


    1 hr 31 min
  • Why the Future of Video Games is Moving Back to the Dinner Table

    This Week In Startups is made possible by:


    Deel - deel.com/twist

    Northwest Registered Agent - northwestregisteredagent.com/twist

    LinkedIn - linkedIn.com/twist


    Today's show:


    Jason sits down with Brynn Putnam, CEO and founder of Board, to learn more about her company's tabletop gaming console. The pair talks about how to raise capital for yet-to-launch hardware projects, the screen-time debate, and how Board is approaching building or buying IP for its family-friendly games. Next, Alex got Heremus's AJ Piplica on the horn to chat hypersonic, autonomous jets. The startup's technology bridges the gap between rockets and airplanes, and may represent the future of warfare, yes, but also fast freight!


    Guest Links:


    Brynn Putnam https://x.com/BrynnPutnam

    Board https://board.fun/

    Board Series A announcement https://techcrunch.com/2026/06/02/board-the-new-game-startup-from-mirror-founder-brynn-putnam-raises-20m-has-already-sold-thousands/

    Mirror https://www.lululemonstudio.com/

    AJ Piplica https://x.com/AJ_Piplica

    Heremus https://www.hermeus.com/

    Heremus Series C announcement https://www.prnewswire.com/news-releases/hermeus-reaches-1-billion-valuation-with-350-million-raise-to-build-todays-fastest-aircraft-for-the-american-warfighter-302735273.html


    Timestamps:


    0:00 Board's Brynn Putnam joins the show

    2:54 Board's proprietary AI software stack

    6:43 Why Board manufactures in Mexico (not China)

    9:21 LinkedIn: Thanks to our partners at LinkedIn! Post your job for free at https://linkedIn.com/twist then promote it to get access to LinkedIn Jobs' new AI assistant.

    9:42 How to raise a Seed round for hardware without a finished product

    15:26 Brynn's daughter and the mermaid example

    17:09 Can Board limit screen time fears?

    18:47 Northwest Registered Agent: Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity — Learn more at https://northwestregisteredagent.com/twist

    22:54 Selling the first 10,000 units

    28:38 Deel - Founders scale faster on Deel. Set up payroll for any country in minutes, hire anyone anywhere, get visas handled fast, and get back to building. Visit https://deel.com/twist to learn more.

    29:42 Why Board is steering away from simple ports toward native IP experiences

    35:32 Hermeus's AJ Piplica joins the show

    35:32 What is Dark Horse?

    43:48 Commercial applications: Cargo, organs, flowers, and trans-Atlantic in 90 minutes

    47:47 Commercial applications: Cargo, organs, flowers, and trans-Atlantic in 90 minutes

    57:00 Dark Horse range and the "reusable first stage" analogy

    58:42 Dark Horse range and the "reusable first stage" analogy

    1:02:42 $350M Series C led by Khosla; total funding now exceeds $500M

    1:03:39 The SpaceX model: get customers to fund your R&D

    1:07:47 Closing: the American Dynamism pitch


    Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com

    Check out the TWIST500: https://www.twist500.com

    Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

    Follow Lon:

    X: https://x.com/lons

    Follow Alex:

    X: https://x.com/alex

    LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm

    Follow Jason:

    X: https://twitter.com/Jason

    LinkedIn: https://www.linkedin.com/in/jasoncalacanis

    Check out all our partner offers: https://partners.launch.co/

    Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

    Check out Jason's suite of newsletters: https://substack.com/@calacanis

    Follow TWiST:

    Twitter: https://twitter.com/TWiStartups

    YouTube: https://www.youtube.com/thisweekin

    Instagram: https://www.instagram.com/thisweekinstartups

    TikTok: https://www.tiktok.com/@thisweekinstartups

    Substack: https://twistartups.substack.com

    1 hr 9 min
  • The hottest running app has nothing to do with speed | E2303

    This Week In Startups is made possible by:Agree - https://agree.comQuo - https://quo.com/TWiSTSuperhuman - https://superhuman.comToday's show:In this double-header, Jason and Lon chat with Louis Phillips, founder of the gamified running app INTVL, which turns a quick job around the block into a worldwide turf war competition. Find out how he grew the app to over 1 million downloads without any paid ads, just making videos from his home office.PLUS Alex sits down with Alice Zhang, CEO of Verge Labs, which pivoted from making drugs to building the AI infrastructure that helps pharma companies develop their own treatments. Find out how they accumulated one of the world's largest proprietary brain datasets and why brain tissue is the "LiDAR of neuroscience."Guests:INTVL: https://www.intvl.com.au/INTVL on Instagram: https://www.instagram.com/intvl.appLouis Phillips on Instagram: https://www.instagram.com/louisphillips12Verge Labs: https://vergelabs.com/Alice Zhang on X: https://x.com/AliceXinliZhangRelevant LinksMeta's Ad Library: https://www.facebook.com/ads/library/Strava: https://www.strava.com/Pokémon Go: https://pokemongo.com/Fitbod: https://fitbod.me/Tonebase: https://www.tonebase.co/Calm: https://www.calm.com/Hamilton Island official site: https://www.hamiltonisland.com.au/"Mr. Inbetween" trailer: https://www.youtube.com/watch?v=EooRG3QhQOYArticle: "Verge Genomics Rebrands as Verge Labs": https://trial.medpath.com/news/verge-genomics-rebrands-as-verge-labs-following-als-drug-trial-failure-pivots-to-ai-driven-target-discoveryEli Lilly: https://www.lilly.com/Chai Discovery: https://www.chaidiscovery.com/Noetik: https://www.noetik.ai/Tempus: https://www.tempus.com/Timestamps:0:00 Louis on building in Melbourne, Australia

    7:44 Why INTVL ignores how fast you run

    9:59 Agree - Stop chasing invoices at https://agree.com and tell them Jason sent you to get 50% off for life!

    15:52 Using gamification for good

    19:10 Powering INTVL's impressive growth

    19:55 Quo (formerly OpenPhone) - Quo gives you a clean, modern way to handle every customer call, text, and thread all in one place. Try it free at https://quo.com/TWiST

    26:16 The future of TWiST Australia

    27:14 Will AI ever cure cancer?

    27:54 Inside Verge's rebrand

    30:31 Superhuman - Get AI that works where you work. Unlock your Superhuman potential at https://superhuman.com

    32:01 Brain tissue as "ground truth"

    36:01 Why brain tissue is so valuable as data

    43:52 Verge's Eli Lilly partnership

    51:34 "You're going to tell me when I'm going to die"

    56:11 How AI could impact drug prices

    58:19 Clinical trial FAILS and how to move onSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisCheck out all our partner offers: https://partners.launch.co/Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com

    1 hr 4 min
  • Why SpaceX Buying Cursor Changes Everything

    This Week In Startups is made possible by:


    Deel - deel.com/twist

    LinkedIn - linkedIn.com/twist

    Northwest Registered Agent - northwestregisteredagent.com/twistPlaud - https://Plaud.ai/twist

    Today's show:


    Anthropic stabbed Cursor in the back. Then SpaceX swooped in with $60 billion. Today, TWiST connects the dots on the biggest deal in AI since the Microsoft-OpenAI partnership, and why it's a warning sign for every startup building on top of a frontier model. Jason is joined by Bling Capital's Ben Ling, Banana Capital's Turner Novak, and co-host Alex to go deep on the future of coding models, the current golden age of venture liquidity, OpenAI's financials, and the 'Four Ds' of venture investing. The show closes with a tribute to Josh Baer, the founder of Capital Factory.


    Guest Links:


    Ben Ling https://x.com/bling0?lang=en

    Bling Capital https://www.blingcap.com/

    Turner Novak https://x.com/TurnerNovak

    Banana Capital https://www.bananacapital.vc/

    Show Links:

    Hanover Park https://www.hanoverpark.com/

    SpaceX buys Cursor https://www.cnbc.com/2026/06/16/spacex-spcx-cursor-acquisition-ipo.html

    Cursor Composer 2.5 https://cursor.com/blog/composer-2-5

    OpenAI financials source https://www.wheresyoured.at/exclusive-openai-financials/

    AMD's new deskside data center https://www.amd.com/en/products/processors/desktops/ryzen/ryzen-ai-halo.html

    Perplexity Model Council https://www.perplexity.ai/hub/blog/introducing-model-council


    Timestamps:


    0:00 Guest introductions

    1:15 Guest introductions

    2:43 SpaceX acquires Cursor for $60B

    6:13 The golden era of M&A

    9:13 Northwest Registered Agent: Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity — Learn more at https://northwestregisteredagent.com/twist

    12:04 Cursor's negative gross margins & the compute problem

    13:22 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off!

    15:04 Rolling your own model: When does it make sense?

    19:35 LinkedIn: Thanks to our partners at LinkedIn! Post your job for free at https://linkedIn.com/twist then promote it to get access to LinkedIn Jobs' new AI assistant.

    22:53 The "headless product" thesis

    28:31 Deel: Founders scale faster on Deel. Set up payroll for any country in minutes, hire anyone anywhere, get visas handled fast, and get back to building. Visit https://deel.com/twist to learn more.

    34:22 OpenAI financials leaked: $13B revenue, $38.5B net loss

    40:13 Where does AI value accumulate?

    45:34 Portfolio Spotlight: Hanover Park

    48:37 Seed stage graduation rates have fallen from 50% to 25%

    54:59 The four Ds of venture: Deal flow, Decisions, Doubling down, Distributions

    1:06:36 How to find 'undiscovered gems'

    1:30:59 Snap Specs AR glasses: $2,195, and a bit chunky

    1:39:29 Tribute to Joshua Baer, Capital Factory's founder


    Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com

    Check out the TWIST500: https://www.twist500.com

    Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

    Follow Lon:

    X: https://x.com/lons

    Follow Alex:

    X: https://x.com/alex

    LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm

    Follow Jason:

    X: https://twitter.com/Jason

    LinkedIn: https://www.linkedin.com/in/jasoncalacanis

    Check out all our partner offers: https://partners.launch.co/

    Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

    Check out Jason's suite of newsletters: https://substack.com/@calacanis

    Follow TWiST:

    Twitter: https://twitter.com/TWiStartups

    YouTube: https://www.youtube.com/thisweekin

    Instagram: https://www.instagram.com/thisweekinstartups

    TikTok: https://www.tiktok.com/@thisweekinstartups

    Substack: https://twistartups.substack.com

    1 hr 42 min
  • The Startup Building the First Hotel on the Moon…

    This Week In Startups is made possible by:


    Every.io - visit every.io

    Sentry.io - sentry.io/twist

    Vanta - vanta.com/twist


    Today's show:

    The next SpaceX won't be building rockets; it'll build the first hotel on the Moon. Today on TWiST, GRU Space founder Skyler Chan brings a brick made from lunar soil into the studio and lays out a plan to manufacture on the Moon as early as next year. We get into the science, the business model, and the regulatory land-grab ahead!

    Then, the US government forces Anthropic to pull Fable 5 and Mythos 5. Jason and Lon unpack what it means when a single AI model can vanish overnight, and the US government's emergency order.

    Stick around for the winner (or winners?!) of the $5,000 AI podcast-companion bounty!


    Timestamps:

    0:00 Knicks playoff run, San Antonio & Texas BBQ (Black's vs. Terry Black's)

    8:23 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off!

    9:52 Guest intro: Skyler Chan, GRU Space — and the lunar-soil brick

    10:29 Every.io - For all of your incorporation, banking, payroll, benefits, accounting, taxes or other back-office administration needs, visit https://every.io

    12:14 Why the next SpaceX builds habitats, not rockets

    15:18 NASA's $20B moon-base signal & the TRL contracting path

    16:13 Business model: from construction contractor to owning lunar land

    18:06 Building the hotel robotically + $1M refundable deposits

    20:00 Sentry - Your team should be focused on shipping features — not chasing down bugs. New users can get $240 in free credits when they go to https://sentry.io/twist and use the code TWIST

    31:09 Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist

    39:28 News: US government blocks Anthropic's Fable 5 & Mythos 5

    41:34 The politics: Hegseth, Sacks, Jassy & the "conspiracy" angle

    1:09:39 Why no single model dependency is safe (multi-model harnesses)

    1:18:47 Bounty results: MySidecast wins $3,000

    1:19:07 Honorable mentions: Couchverse (Lemon Slice) & Convalenz

    1:29:44 Next bounty: the Annotated app

    🔗 Links & Resources Mentioned:

    Guest & company

    Skyler Chan: Founder, GRU Space → https://www.ycombinator.com/companies/galactic-resource-utilization-space-inc-gru-space

    GRU Space (Galactic Resource Utilization): YC startup building lunar-regolith bricks and a robotic Moon hotel → https://www.ycombinator.com/companies/galactic-resource-utilization-space-inc-gru-space

    GRU Space lunar hotel bookings → https://payloadspace.com/gru-space-opens-bookings-for-planned-lunar-hotel/


    🎙️ About the Guest:

    Skyler Chan is the founder of GRU Space (Galactic Resource Utilization), a Y Combinator–backed startup developing a payload factory that manufactures bricks from lunar regolith to build the first robotic hotel on the Moon.

    Follow GRU Space → https://www.ycombinator.com/companies/galactic-resource-utilization-space-inc-gru-space

    Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com

    Check out the TWIST500: https://www.twist500.com

    Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

    Follow Lon:

    X: https://x.com/lons

    Follow Alex:

    X: https://x.com/alex

    LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm

    Follow Jason:

    X: https://twitter.com/Jason

    LinkedIn: https://www.linkedin.com/in/jasoncalacanis

    Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

    Check out Jason's suite of newsletters: https://substack.com/@calacanis

    Follow TWiST:

    Twitter: https://twitter.com/TWiStartups

    YouTube: https://www.youtube.com/thisweekin

    Instagram: https://www.instagram.com/thisweekinstartups

    TikTok: https://www.tiktok.com/@thisweekinstartups

    Substack: https://twistartups.substack.com

    1 hr 41 min
  • SpaceX IPO Day: What Wall St. and the media missed | E2300

    This Week In Startups is made possible by:

    Plaud https://Plaud.ai/twist

    Pilot https://pilot.com/twist

    Agree https://agree.com

    IM8 Health https://IM8health.com/twist


    After watching Elon build out his rocket (and AI) company over the past 20 years, Jason celebrates the SpaceX IPO on a new TWiST. He explains why some investments are evaluated based on earnings and current numbers, while other stocks are bets on expensive visions for the future, and why SpaceX why likely pay off across multiple time horizons.

    PLUS Polsia solo founder Ben Cera is back with guidance for founders on creating a "Purple Cow": a unique experience that makes their brand memorable.


    Guest:

    Ben Cera on X: https://x.com/Bencera

    Polsia: https://polsia.com/

    Polsia on X: https://x.com/polsia

    Ben on TWiST E2256 (Feb 2026): https://www.youtube.com/watch?v=QCce8e02Isw


    Relevant Links:

    SpaceX: https://www.spacex.com/

    SPCX on Yahoo Finance: https://finance.yahoo.com/quote/SPCX/

    Starlink: https://www.starlink.com/

    Planet Labs: https://www.planet.com/

    Palantir: https://www.palantir.com/

    Valor Equity Partners: https://www.valorep.com/

    Seth Godin's "Purple Cow" on Amazon: https://www.amazon.com/Purple-Cow-New-Transform-Remarkable/dp/1591843170

    Uber Ice Cream stunt article: https://finance.yahoo.com/news/ubers-brilliant-marketing-stunt-hail-195946535.html

    Hillsborough Flintstones House article: https://www.sfgate.com/travel/article/The-Flintstone-House-is-now-for-rent-on-Airbnb-10420107.php

    "19 Hours Inside the Airbnb X-Mansion" article: https://www.theringer.com/2024/05/29/pop-culture/x-mansion-airbnb-x-men-icons-experience

    Was The Pepsi Challenge based on LIES? https://www.historyoasis.com/post/the-pepsi-challenge

    CloudKitchens: https://cloudkitchens.com/

    Cluely: https://cluely.com/

    Timestamps:


    0:00 SpaceX IPO details

    2:12 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off!

    7:21 The voting vs. weighing investment framework

    9:41 Pilot: Focus on your product, let Pilot handle your bookkeeping. Pilot provides the most reliable accounting, CFO, and tax services for startups and small businesses. Head to https://pilot.com/twist and get $1,200 off your first year.

    19:53 Agree - Stop chasing invoices at https://agree.com and tell them Jason sent you to get 50% off for life!

    22:25 The media's SpaceX criticisms and "hot takes"

    23:54 Ben Cera of Polsia is back

    26:53 Why Jason says no to a free tier

    29:10 IM8 Health: Start feeling like your best self every day. Go to https://IM8health.com/twist and use the code TWiST to get a free welcome kit, five free travel sachets, and 10% off your order.

    34:27 The wisdom of Seth Godin's "Purple Cow"

    50:37 The "Pepsi Challenge" model

    1:05:45 Lon got a dog, Jason got routers

    1:10:37 The YouTuber to movie theater pipeline

    1:15:20 Jason's new favorite travel bag

    Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com

    Check out the TWIST500: https://www.twist500.com

    Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

    Follow Lon:

    X: https://x.com/lons

    Follow Alex:

    X: https://x.com/alex

    LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm

    Follow Jason:

    X: https://twitter.com/Jason

    LinkedIn: https://www.linkedin.com/in/jasoncalacanis

    Check out all our partner offers: https://partners.launch.co/

    Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

    Check out Jason's suite of newsletters: https://substack.com/@calacanis

    Follow TWiST:

    Twitter: https://twitter.com/TWiStartups

    YouTube: https://www.youtube.com/thisweekin

    Instagram: https://www.instagram.com/thisweekinstartups

    TikTok: https://www.tiktok.com/@thisweekinstartups

    Substack: https://twistartups.substack.com

    1 hr 20 min
  • Why the most expensive Seed deals are the cheapest | E2299

    This Week In Startups is made possible by:


    NetSuite - Netsuite.com/TWiST

    Deel - Deel.com/TWiST

    Squarespace - Squarespace.com/TWiST


    Two days before SpaceX launches the largest IPO in history at a flat $135/share, our VC roundtable drops a scorcher: The top 1% of seed deals might actually be underpriced. Plus: the "Sequoia scam" dual-tranche controversy, tokens-for-equity deals, and whether Claude Fable 5 is a true step function.

    Tomasz Tunguz (Theory Ventures), Michael Downing (Castalia Capital), and Paige Doherty (Behind Genius Ventures) join Alex to go deep on Seed investing, startup economics, AI spend, and the impact of smarter AI on the founder journey.


    Guest Links:


    Tomasz Tunguz: https://x.com/ttunguz

    Theory Ventures: https://theoryvc.com/

    Michael Downing: https://www.linkedin.com/in/michaeldowning/

    Castalia Capital: https://castalia.capital/

    Paige Doherty: https://x.com/paigefinnn

    Behind Genius Ventures: https://www.behindgeniusventures.com

    Show Links:

    Anthropic's IPO announcement: https://www.anthropic.com/news/confidential-draft-s1-sec

    OpenAI's IPO announcement: https://openai.com/index/openai-submits-confidential-s-1/

    Bending Spoons F-1 filing: https://www.sec.gov/Archives/edgar/data/2004711/000110465926071170/tm2613674-7_f1.htm

    SpaceX IPO filing: https://www.sec.gov/Archives/edgar/data/1181412/000162828026040364/spaceexplorationtechnologib.htm

    Brendan Foody's post on Sequoia: https://x.com/BrendanFoody/status/2063470286515683759

    Claude Fable 5: https://www.anthropic.com/news/claude-fable-5-mythos-5

    OpenRouter data on Chinese models: https://openrouter.ai/rankings?view=day

    Saronic: https://www.saronic.com/

    MotherDuck: https://motherduck.com/

    Nox Metals: https://noxmetals.co/


    Timestamps:


    0:00 Tomasz Tunguz, Michael Downing & Paige Doherty join

    2:07 The SpaceX IPO and the IPO window

    4:22 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off!

    6:30 The new bar: 10x growth (not 3x) to raise a great Series A

    8:46 Net-new AI budgets

    9:46 Squarespace: Turn your idea into a beautiful website! Go to https://www.squarespace.com/twist for a free trial. When you're ready to launch, use offer code TWIST to save 10% off your first purchase of a website or domain.

    11:09 How some founders are outgrowing venture capital

    11:44 The power pendulum swings back to founders

    12:46 SpaceX vs. OpenAI vs. Anthropic: Which IPO is most enticing?

    19:53 Deel - Founders scale faster on Deel. Set up payroll for any country in minutes, hire anyone anywhere, get visas handled fast, and get back to building. Visit https://deel.com/twist to learn more.

    26:07 Tokens-for-equity, GPU-hours-for-equity & the financialization of compute

    28:35 Founders airing VC dirty laundry (napping VCs included)

    29:56 Netsuite - The business landscape is very chaotic right now. That's why you need NetSuite, by Oracle. Get the free business guide Demystifying AI at https://Netsuite.com/TWiST

    36:38 Claude Fable 5 first impressions: pricing, benchmarks & orchestration

    45:42 Where value accrues: application layer vs. models vs. private data

    1:00:06 Nationalization of AI labs: Bernie Sanders, Sam Altman & Trump agree?!

    1:01:25 Portfolio spotlights: Saronic, MotherDuck, and Nox Metals


    Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com

    Check out the TWIST500: https://www.twist500.com

    Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

    Follow Lon:

    X: https://x.com/lons

    Follow Alex:

    X: https://x.com/alex

    LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm

    Follow Jason:

    X: https://twitter.com/Jason

    LinkedIn: https://www.linkedin.com/in/jasoncalacanis

    Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

    Check out Jason's suite of newsletters: https://substack.com/@calacanis


    1 hr 9 min
  • The AI Tutor That Makes Kids Actually Think | E2298

    The AI Tutor That Makes Kids Actually Think | E2298


    This Week In Startups is made possible by:


    Northwest Registered Agent https://northwestregisteredagent.com/twist


    LinkedIn Jobs https://LinkedIn.com/twist


    Shopify https://shopify.com/twist


    Plaud https://Plaud.ai/twist


    Today's show:


    *Schools teach kids to memorize formulas. AI helps them skip thinking entirely. Brilliant founder Sue Khim joins TWiST to tell us how her new AI tutor, Koji, uses the Socratic Method to help students solve complex problems on their own. Find out why she says "People aren't anti-AI. They're anti-being replaced and anti-slop."

    PLUS Jason's take on the VC horror stories going around X… and his own anecdote about the tenacity and passion of legendary investor John Doerr.


    Guest:


    Sue Khim on X: https://x.com/suekhim

    Brilliant: https://brilliant.org/

    Viral Koji launch video: https://x.com/suekhim/status/2060378988606878147


    Relevant Links:


    Viral Greg Isenberg post about VCs: https://x.com/gregisenberg/status/2061794787825479818

    Travis Kalanick's story: https://x.com/travisk/status/2062224472426365045

    Matthew Prince's stories: https://x.com/eastdakota/status/2062860530360959273

    John Doerr on X: https://x.com/johndoerr

    Roelof Botha on X: https://x.com/roelofbotha

    Michael Moritz on LinkedIn: https://www.linkedin.com/in/michaelmoritz/

    Mohr Davidow Ventures: https://mdv.com/

    Jason's book "Angel: How to Invest in Technology Startups": https://www.amazon.com/Angel-Invest-Technology-Startups-Timeless-Investor/dp/0062560700


    Timestamps:


    0:00 Sue Khim's Alltuition origin story

    1:41 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off!

    4:10 Brilliant: from launch to product market pull

    10:46 Northwest Registered Agent - Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity — Learn more at https://northwestregisteredagent.com/twist

    15:08 Pricing against tutors, not apps

    19:25 LinkedIn Jobs - Hire right, the first time. Post your first job and get $100 off towards your job post at https://LinkedIn.com/twist

    21:22 Koji demo

    24:11 Keeping Brilliant local while expanding

    30:22 Shopify - Turn those What Ifs into sales with the e-commerce platform powering millions of businesses. Sign up for your $1-per-month trial today at https://shopify.com/twist

    40:10 Every founder has a VC horror story

    44:33 John Doerr went the extra mile to hear JCal's pitch

    52:55 The LAUNCH investment strategy

    Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com

    Check out the TWIST500: https://www.twist500.com

    Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

    Follow Lon:

    X: https://x.com/lons

    Follow Alex:

    X: https://x.com/alex

    LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm

    Follow Jason:

    X: https://twitter.com/Jason

    LinkedIn: https://www.linkedin.com/in/jasoncalacanis

    Check out all our partner offers: https://partners.launch.co/

    Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

    Check out Jason's suite of newsletters: https://substack.com/@calacanis

    Follow TWiST:

    Twitter: https://twitter.com/TWiStartups

    YouTube: https://www.youtube.com/thisweekin

    Instagram: https://www.instagram.com/thisweekinstartups

    TikTok: https://www.tiktok.com/@thisweekinstartups

    Substack: https://twistartups.substack.com

    1 hr 1 min
  • Anthropic wants to slow AI down and Bernie wants 50%: JCal Reacts | E2297

    This Week In Startups is made possible by:


    Grasshopper Bank https://grasshopper.bank/twist

    Vanta https://www.vanta.com/twist

    Render https://render.com/twist

    Plaud https://Plaud.ai/twist


    Today's show:


    Anthropic wrote a blog post calling for a global AI slowdown. Meanwhile, Sen. Bernie Sanders wants the government to seize 50% of every major AI company's stock. Find out why JCal is reconsidering universal basic (or even high!) income policies, and why he thinks the 2028 presidential election will likely come down to AI policies.

    PLUS a live ComfyUI demo from founder Yoland Yan. Find out why the free-to-use open-source node-based platform has become a crucial part of millions of designers' and VFX experts' workflows, and how their tool has been used to create everything from "The Wizard of Oz" at the Vegas Sphere to those viral Coca-Cola holiday ads.


    Guest


    Yoland Yan: http://x.com/yoland_yan

    ComfyUI: https://comfy.org/


    AI Models and Tools


    Ideogram 4.0: https://ideogram.ai/models/4.0/

    Stable Diffusion: https://stability.ai/

    LTX Video: https://github.com/Lightricks/LTX-Video

    LoRa: https://huggingface.co/docs/diffusers/training/lora

    Google Veo: https://deepmind.google/models/veo/


    Relevant Links:


    Anthropic: "When AI Builds Itself": https://www.anthropic.com/institute/recursive-self-improvement

    Bernie Sanders: "The Public Should Own Half of the Big AI Companies": https://www.sanders.senate.gov/op-eds/the-public-should-own-half-of-the-big-a-i-companies/

    Bloomberg: "Sam Altman-Backed Group Completes Largest US Study on Basic Income": https://www.bloomberg.com/news/articles/2024-07-22/ubi-study-backed-by-openai-s-sam-altman-bolsters-support-for-basic-income


    Timestamps:


    0:00 Guest 1: Yoland Yan, ComfyUI — live demo intro

    2:06 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off!

    4:34 Guest 1: Yoland Yan, ComfyUI — live demo intro

    9:47 Grasshopper Bank - Time is money. Don't waste either. Go to https://grasshopper.bank/twist and get an exclusive $500 cash bonus just for opening an account.

    20:05 Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist

    22:24 What is Outpainting?

    30:01 Render - Find out why 5 million developers are already using the all-in-one cloud platform, Render. Go to https://render.com/twist and apply for the Render Startup Program to get $500-$100,000 in free credits, depending on your stage and backers.

    32:13 Jason's insider sales team advice

    38:42 LA mayoral race: Bass vs. Pratt

    42:25 Anthropic wants AI to slow down?

    48:45 Will Sen. Sanders' argument resonate with the public?

    59:39 Why 2028 will be the AI jobs election

    1:05:32 Brian Chesky's new AI lab

    1:15:21 Jason's "Mandalorian and Grogu" review

    1:18:53 YouTubers take over the box office

    1:24:16 Dean Potter vs. Alex Honnold

    Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com

    Check out the TWIST500: https://www.twist500.com

    Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

    Follow Lon:

    X: https://x.com/lons

    Follow Alex:

    X: https://x.com/alex

    LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm

    Follow Jason:

    X: https://twitter.com/Jason

    LinkedIn: https://www.linkedin.com/in/jasoncalacanis

    Check out all our partner offers: https://partners.launch.co/

    Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

    Check out Jason's suite of newsletters: https://substack.com/@calacanis

    Follow TWiST:

    Twitter: https://twitter.com/TWiStartups

    YouTube: https://www.youtube.com/thisweekin

    Instagram: https://www.instagram.com/thisweekinstartups

    TikTok: https://www.tiktok.com/@thisweekinstartups

    Substack: https://twistartups.substack.com

    1 hr 34 min
  • The project SpaceX's first employee raised $500M for

    This Week In Startups is made possible by:


    Northwest Registered Agent - NorthwestRegistereAagent.com/TWIST

    Every - Every.io

    Sentry - Sentry.io/TWIST


    Today's show:

    Want to get to space? Several launch companies can help you. SpaceX, Rocket Lab, the Russians, the list goes on. But what about once you make it upstairs, then what? Impulse Space CEO and CTO Tom Mueller is building the next stage of our orbital economy. With its Mira and Helios spacecraft, we'll soon be able to take mass from lower orbits to higher orbits, or even to the Moon, with ease.

    Meanwhile, venture capitalists are enamored with the idea of humanoid robots — robots share our shape, our work environment, and even our tools. But startups like Dusty Robotics are taking a different tack; instead of building human-shaped robots, Dusty has built a small, wheeled 'bot that can mark out building sites quickly and accurately. And it's doing more revenue than all humanoid robotics companies combined, I reckon. Dusty's CEO, Dr. Tessa Lau, joins Alex to go deep on purpose-built robots in today's build-crazy market.


    Timestamps:


    0:00 Blue Origin, and why fixing things in orbit is hard

    2:19 What Mira is and what it does

    4:35 Why was the commercial demand for Mira softer than expected

    5:20 Space Force demand and the GEO-capable Mira

    7:08 Helios: a "rocket on top of a rocket."

    10:10 Sentry - Your team should be focused on shipping features — not chasing down bugs. New users can get $240 in free credits when they go to https://sentry.io/twist and use the code TWIST

    11:35 How Helios beats Falcon Heavy on price ($25M)

    13:35 Reusability, in-orbit refueling, and propellant depots

    15:38 Landers, the Moon base, and "Mega Helios."

    18:52 NSSL and the politics of flying government payloads

    20:16 Every.io - For all of your incorporation, banking, payroll, benefits, accounting, taxes or other back-office administration needs, visit https://every.io

    20:51 Why the Moon matters: megastructures and data centers in space

    25:09 The space talent market and the SpaceX "mafia."

    30:16 Northwest Registered Agent: Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity — Learn more at https://northwestregisteredagent.com/twist


    Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com

    Check out the TWIST500: https://www.twist500.com

    Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

    Follow Lon:

    X: https://x.com/lons

    Follow Alex:

    X: https://x.com/alex

    LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm

    Follow Jason:

    X: https://twitter.com/Jason

    LinkedIn: https://www.linkedin.com/in/jasoncalacanis

    Thank you to our partners:


    Check out all our partner offers: https://partners.launch.co/

    Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

    Check out Jason's suite of newsletters: https://substack.com/@calacanis

    Follow TWiST:

    Twitter: https://twitter.com/TWiStartups

    YouTube: https://www.youtube.com/thisweekin

    Instagram: https://www.instagram.com/thisweekinstartups

    TikTok: https://www.tiktok.com/@thisweekinstartups

    Substack: https://twistartups.substack.com


    1 hr 2 min

About This Week in Startups

From the publisher's feed

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world's greatest founders, operators, investors, and innovators.

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