Vincent and Rich visit Fred Murphy to hear about his wide-ranging career in virology, spanning many institutions, involving dangerous viruses like rabies virus, Ebolavirus (he took that famous iconic image), Marburg virus, Lassa virus, coronaviruses, and later writing a history of the field.

Daniel Griffin provides a clinical update on COVID-19, then Sabra Klein joins us to discuss the effect of sex, gender, and age on viral infectious disease, including COVID-19.

Peter Daszak joins TWiV to explain the work of EcoHealth Alliance in surveillance of bats in China for SARS-related coronaviruses to provide the information needed to prevent future pandemics, and why NIH recently withdrew financial support for their work.

Emmie de Wit joins TWiV to explain her work on the pathogenesis of infection with SARS-CoV-2 in rhesus macaques, including studies on remdesivir and vaccine candidate.

Daniel Griffin provides a clinical update on COVID-19, then we review an Ad5 vectored SARS-CoV-2 vaccine, reports on remdesivir and hydroxychloroquine, a drug repurposing study, why some patients infect many others, reducing viral transmission, and much more, including listener email.

Jon Yewdell returns to explain studies on detection of antibodies and T cell epitopes in patients who have recovered from COVID-19.

Raul Rabadan joins TWiV to explain the use of computational biology to demonstrate how recombination and mutation led to emergence of SARS-CoV-2.

Daniel Griffin provides a clinical update on COVID-19, then we review TETRIS by Paterson NJ, modeling the effects of intervention in the US on cases and deaths, mixing PCR and serology data, and much more, including listener email.

Vincent, Kathy and Rich discuss COVID-19 research paper overload, Moderna's mRNA vaccine Phase I results, increase of ACE2 RNA by cigarette smoke, and answer listener questions.

Vincent speaks with Peter Daszak, President of EcoHealth Alliance, a global nonprofit organization dedicated to protecting wildlife and public health from the emergence of disease.