Breastcancer.org Podcast

Treatment After CDK4/6 Inhibitors

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CDK4/6 inhibitors are used to treat both early-stage and advanced-stage hormone receptor-positive, HER2-negative breast cancer. 


The CDK4/6 inhibitors are:

  • Ibrance (chemical name: palbociclib)
  • Kisqali (chemical name: ribociclib)
  • Verzenio (chemical name: abemaciclib)


    At the 2023 San Antonio Breast Cancer Symposium, Dr. Stephanie Graff moderated an educational session to help people and their doctors decide on treatments after a CDK4/6 inhibitor has stopped working.


    Listen to the podcast to hear Dr. Graff explain:

    • how the oral SERD, Orserdu (chemical name: elacestrant), might be used
    • how PARP inhibitors, such as Lynparza (chemical name: olaparib) or Talzenna (chemical name: talazoparib) might be used
    • why using a CDK4/6 inhibitor after another CDK4/6 inhibitor probably won’t be used
      • ...more
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      Breastcancer.org PodcastBy Breastcancer.org
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