The TWiPlicates solve the case of the Child With Retinal Granuloma, and discuss an association of the complement protein collectin-11 with the pathophysiology of Chagas disease.

Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin

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Links for this episode:

• Chagas disease pathophysiology and collectin-11 (PLoS NTD)
• Hero: Theobald Smith
• Image credit: Toxocara canis by Ben Liffner
• Letters read on TWiP 170

Case Study for TWiP 170

3 yo girl, same context: mobile clinic in Bocas del Toro archipelago. Small village on remote island. Initially had red eye, rubbing a lot, mother noticed she seemed to have vision loss. On exam ophthalmologist did fundoscopic exam, sees band keratopathy, calcium on the cornea, and outer retinal punctate lesions.

Send your case diagnosis, questions and comments to [email protected]

Music by Ronald Jenkees