In this episode, Dr. Morgentaler and Dr. Brandon talk about how testosterone therapy can improve biological aging by enhancing vitality, reducing health risks, and potentially reversing some aging markers in men with low testosterone levels. 00:18 Understanding Biological vs. Chronological Age The hosts explain the difference between biological age, which reflects overall health and disease risk, and chronological age, determined simply by years lived. 03:18 Testosterone's Impact on Vitality and Energy Testosterone deficiency is linked to feelings of fatigue, irritability, and a diminished sense of vitality, which can be reversed with therapy, improving overall energy and quality of life. 07:32 Scientific Studies on Testosterone and Aging Key studies highlight how testosterone upregulates the anti-aging Klotho gene and improves epigenetic markers, potentially reducing biological age and associated health risks. 13:27 Risks of Low Testosterone Levels Low testosterone is associated with serious health risks, including increased chances of diabetes, obesity, osteoporosis, heart disease, and even aggressive prostate cancer. 19:55 Testosterone Therapy and Practical Advice The episode concludes with practical insights on testosterone therapy, emphasizing its potential as a reversible trial to improve health while addressing misconceptions about long-term dependency and fertility concerns. Resources: The Male Hormone by Paul Derquiff (1945) With Dr. Abraham Morgentaler and Dr. Marianne Brandon Listen to the podcast on all of your favorite platforms: Apple: https://podcasts.apple.com/ec/podcast/the-sex-doctors/id1761813985?l=en-GB Spotify: https://open.spotify.com/show/0apSFzquJXKoOGnmI6ndgT?si=e5a1e482c7ca46c7 Find us on: Instagram: https://www.instagram.com/thesexdoctors?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw== Facebook: https://www.facebook.com/thesexdoctors YouTube: https://www.youtube.com/@thesexdoctorspod TikTok: https://www.tiktok.com/@thesexdoctor LinkedIn (Dr. Abraham): https://www.linkedin.com/in/abraham-morgentaler-md-81628b6 LinkedIn (Dr. Marianne): https://www.linkedin.com/in/mariannebrandon-59224513 X (Dr. Abraham): https://x.com/DrMorgentaler X (Dr. Marianne): https://x.com/drbrandon #TestosteroneTherapy #BiologicalAging #HealthOptimization