Inside Health

What next for Alzheimer's treatment?


Listen Later

The first drugs to slow Alzheimer's progression have been making headlines around the world. For researchers in the field, the arrival of these two therapies called Lecanemab and Donanemab is testament to decades of advancements in the field of Alzheimer's research because for the first time they go further than modifying the symptoms and have been shown in trials to slow down cognitive decline. For patients and families these treatments offer hope that the amount of quality time they'll have together could be lengthened.

Around the world regulatory bodies are weighing up their effectiveness, safety and cost. In the UK by the Medicines and Healthcare products Regulatory Agency (MHRA)

has approved Lecanemab and Donanemab for use but the National Institute for Health and Care Excellence (NICE) rejected them for use in the NHS on the basis the benefit to patients did not outweight the cost, although they could still be available privately.

Presenter James Gallagher examines the decision with Professor of Public Health Carol Brayne from the University of Cambridge and neuroscientist Professor Tara Spires-Jones from the University of Edinburgh. Then, looking forward, he meets scientists searching for future treatments including Dr Emma Mead, chief scientist at the Alzheimer's UK Drug Discovery Institute at the University of Oxford, Dr Ashvini Keshavan, co-lead of University College London's ADAPT blood biomarker trial, Selina Wray, Professor of Molecular Neuroscience and Alzheimer's Research UK Senior Research Fellow at University College London, and UK Dementia Research Institute Emerging Leader Dr Claire Durrant.

This programme was produced in partnership with The Open University.

Presenter: James Gallagher

Producer: Tom Bonnett
Editor: Holly Squire

...more
View all episodesView all episodes
Download on the App Store

Inside HealthBy BBC Radio 4

  • 4.5
  • 4.5
  • 4.5
  • 4.5
  • 4.5

4.5

72 ratings


More shows like Inside Health

View all
In Our Time by BBC Radio 4

In Our Time

5,447 Listeners

The Documentary Podcast by BBC World Service

The Documentary Podcast

1,802 Listeners

Global News Podcast by BBC World Service

Global News Podcast

7,626 Listeners

Science Weekly by The Guardian

Science Weekly

419 Listeners

Health Check by BBC World Service

Health Check

89 Listeners

6 Minute English by BBC Radio

6 Minute English

1,747 Listeners

Learning English Conversations by BBC Radio

Learning English Conversations

1,083 Listeners

More or Less: Behind the Stats by BBC Radio 4

More or Less: Behind the Stats

892 Listeners

The Food Programme by BBC Radio 4

The Food Programme

267 Listeners

The Infinite Monkey Cage by BBC Radio 4

The Infinite Monkey Cage

2,092 Listeners

Newshour by BBC World Service

Newshour

1,039 Listeners

The Life Scientific by BBC Radio 4

The Life Scientific

229 Listeners

All in the Mind by BBC Radio 4

All in the Mind

63 Listeners

BBC Inside Science by BBC Radio 4

BBC Inside Science

404 Listeners

CrowdScience by BBC World Service

CrowdScience

474 Listeners

The Liz Earle Wellbeing Show by Liz Earle

The Liz Earle Wellbeing Show

237 Listeners

The Doctor's Kitchen Podcast by Dr Rupy Aujla

The Doctor's Kitchen Podcast

590 Listeners

Sliced Bread by BBC Radio 4

Sliced Bread

139 Listeners

13 Minutes Presents: The Space Shuttle by BBC World Service

13 Minutes Presents: The Space Shuttle

4,197 Listeners

Americast by BBC News

Americast

704 Listeners

You're Dead to Me by BBC Radio 4

You're Dead to Me

2,984 Listeners

Just One Thing - with Michael Mosley by BBC Radio 4

Just One Thing - with Michael Mosley

225 Listeners

Saving Lives In Slow Motion by Dr Ayan Panja

Saving Lives In Slow Motion

29 Listeners

ZOE Science & Nutrition by ZOE

ZOE Science & Nutrition

2,047 Listeners

What's Up Docs? by BBC Radio 4

What's Up Docs?

96 Listeners