Well Beyond 40

Why Zane Griggs Believes Extreme Biohacking Fails You


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Are you unknowingly masking chronic physical burnout under the guise of disciplined biohacking?


I invited Zane Griggs on the show to talk about the sneaky ways high performers can turn discipline into burnout, especially after 40. Zane brings such a grounded perspective on carbs, fasting, testosterone, recovery, and the lab markers that can reveal when your body is stressed instead of thriving. In this episode, we’re cutting through the noise so you can build a strong, sustainable health plan that still leaves room for joy, connection, and real life.

What you’ll learn:

(03:20) High performers often crash their health by overusing extreme stress levers like chronic caloric restriction and over-exercising.

(05:10) Modern biohacking and rigid morning routines can accidentally manifest as a new form of physical burnout disguised as discipline.

(09:45) Glucagon acts as an under-discussed initial stress hormone that can chronically elevate your blood sugar when your body is under-fueled.

(11:24) Long-term adherence to strictly low-carb or ketogenic diets can inadvertently destroy your body's innate metabolic flexibility.

(17:55) Eliminating plant foods on a permanent carnivore diet starves crucial gut bacteria, damaging your immune system and intestinal lining.

(26:36) Fasting insulin is frequently omitted from standard blood panels because many conventional practitioners lack the training to interpret optimal ranges.

(30:07) Adding tests for reverse T3 and free testosterone provides an accurate baseline of how stress is affecting your metabolic and endocrine systems.

(42:08) Testosterone is a vital human hormone for women that safely restores libido, protects muscle mass, and eliminates stubborn fat.


Love the podcast? Here’s what to do:


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Text a screenshot to me at 813-565-2627 and wait for a personal reply because your voice is so important to me.


Full show notes (including all links mentioned): https://jjvirgin.com/zane

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Well Beyond 40By JJ Virgin

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