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In this episode of Decoding Health, Dr. Urban Kiernan is joined by returning guest Dr. S. Thaddeus Connelly, a triple doctorate oral and maxillofacial surgeon, for a compelling conversation that connects the dots between sleep, oral health, gut function, and brain performance. Dr. Connelly explains how obstructive sleep apnea disrupts the brain’s glymphatic system during non-REM sleep, impairing its ability to clear waste and increasing the risk of cognitive decline. The discussion dives into the importance of gut health, the role of the mouth as the beginning of the digestive tract, and the systemic effects of chronic inflammation caused by gum disease, especially in areas like the molars and wisdom teeth. We discuss commensal bacteria, nitric oxide production, and the impact of oral hygiene habits on overall health. We touch on myths around mouthwash, highlighting helpful products like Gengyve, and explore how bacterial colonies in the mouth can influence heart disease, diabetes, and more. This episode is packed with insightful takeaways on how taking care of your mouth and sleep may be the key to protecting your brain and body. 

Dr. S. Thaddeus Connelly DDS, MD, PhD, FACS, is a renowned Oral and Maxillofacial Surgeon and Full Professor at the University of California, San Francisco. With degrees in Dentistry, Medicine, and a Doctorate, Dr. Connelly's exceptional skills have earned him the prestigious Fellow of the American College of Surgeons designation. As Co-Founder of Boutique Venture Partners, a healthcare-focused venture capital firm, and CEO of Incline Village Global Farma, he combines clinical expertise with entrepreneurial acumen to drive advancements in medical research and patient care. At UCSF, he mentors future leaders and engages in cutting-edge research, while through his ventures, he fosters healthcare innovation and improves global health outcomes. Dr. Connelly's career is marked by leadership, innovation, and a passion for enhancing patient care and contributing to the medical community.  

https://www.linkedin.com/in/stephen-thaddeus-connelly-8954024b/
https://gengyveusa.com/
https://thequantumdistillery.substack.com/
https://www.boutiquevc.com/

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