Modern Psychedelics

096 | Psychedelic Pharmacology 101: Contradictions & Tapering Guidelines You Should Know w/ Ben Malcolm (AKA The Spirit Pharmacist)


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In this episode, Ben Malcolm (the Spirit Pharmacist) brings us into the intersection of psychedelics and pharmacology. We discuss practical considerations, such as guidelines for safely tapering off SSRIs before embarking on a psychedelic experience and navigating contraindications between psychedelics and antidepressants.

Throughout the conversation, Ben offers valuable insights into crafting tapering protocols, including the intricacies of microdosing and potential risks like valvular heart disease associated with psilocybin mushrooms. We explore various facets of psychedelic use, including important considerations like drug interactions and the reintroduction of substances post-Iboga/Ibogaine treatment. Ben sheds light some light on the enigmatic reactivations associated with 5-MeO-DMT and the complex interplay between cannabis and psychedelics.

This conversation provides a comprehensive guide for listeners navigating the terrain where psychedelics meet pharmaceuticals, offering valuable insights and considerations for safe and transformative experiences.


Topics Covered:

  • How psychedelics fit into pharmaceuticals
  • How ketamine freed Ben from chronic pain
  • Guidelines from tapering off of SSRIs before a psychedelic experience
  • Psychedelics that are compatible or not with anti-depressants
  • What to consider when embarking on a tapering protocol
  • Microdosing and tapering
  • The risk of valvular heart disease with psilocybin mushrooms
  • Drug interactions with psychedelics to be aware of
  • Reintroducing substances/alcohol after Iboga/Ibogaine
  • The mystery of 5-MeO-DMT reactivations and Cannabis


Show Links:

  • Apply for 1:1 Coaching with Lana
  • The Spirit Pharmacist website
  • Episode 84 with Steve Rio (Spotify | Apple | YouTube)


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👉 ⁠⁠⁠⁠⁠⁠FREE Intention Setting Journal for Psychedelic Experiences⁠⁠⁠⁠⁠⁠

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👉 ⁠⁠⁠⁠⁠⁠Ceremony Checklist for Safe Plant Medicine Journeys⁠⁠⁠⁠⁠

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DISCLAIMER: Modern Psychedelics does not endorse or support the illegal consumption of any substances. This show is meant for entertainment purposes only. Modern Psychedelics does not sell or promote the sale of any illegal substances. The thoughts, views and opinions on this show should not be taken as life advice, medicinal advice, or therapeutic guidance. 

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