In this episode, Dr. Shawn Tassone examines a paradigm-shifting study from the Journal of the North American Menopause Society that demolishes decades of unfounded hysteria surrounding hormone replacement therapy for women over 65.

The research reveals that HRT—specifically estrogen therapy—administered beyond age 65 correlates with significant risk reductions across multiple disease categories: mortality, breast cancer, lung cancer, colorectal cancer, congestive heart failure, venous thromboembolism, atrial fibrillation, myocardial infarction, and dementia. The findings underscore the critical importance of precision medicine approaches utilizing individualized protocols, lower dosing strategies, and non-oral delivery methods for optimal clinical outcomes.

Episode Highlights

• The NAMS study that's rewriting the hormone therapy playbook for women over 65
• Quantifiable risk reductions across nine major disease categories, including the holy grail of mortality reduction
• Why the data on breast cancer, lung cancer, and colorectal cancer risk reduction should make us question everything we thought we knew
• The cardiovascular benefits that contradict decades of clinical paranoia: reduced congestive heart failure, venous thromboembolism, atrial fibrillation, and heart attacks
• Dementia risk reduction—because apparently estrogen is neuroprotective, not neurotoxic
• The vindication of individualized hormone therapy protocols using lower doses and transdermal delivery
• Estrogen monotherapy combined with progesterone: the life-extending intervention hiding in plain sight
• How this research obliterates the arbitrary age-based cutoffs that have dominated clinical practice
• Why your patients over 65 deserve a risk-benefit analysis based on actual science, not medical mythology
• The clinical implications for practitioners ready to abandon fear-based prescribing in favor of evidence-based care

Episode Resources

Dr. Shawn Tassone's Practice | https://www.drshawntassone.com

Dr. Shawn Tassone's Book | The Hormone Balance Bible

Dr. Shawn Tassone's Integrative Hormonal Mapping System | Hormone Archetype Quiz

Thank you to our sponsor, Purality Health!

The question isn't which supplements to take—it's whether your body can absorb them. Most traditional supplements fall victim to stomach acid before delivering benefits.

Purality Health's micelle liposomal technology creates a double-layer protective system that shields nutrients from stomach acid destruction while facilitating direct bloodstream absorption—making supplements up to 800% more effective.

For perimenopausal and menopausal patients, I recommend their Vitamin D3 with K2 for bone density and mood regulation, and their exceptional magnesium formula for sleep and muscle tension.

As a physician, I value their commitment to quality: cGMP-compliant facilities, purity testing, and organic, non-GMO ingredients without unnecessary fillers.

Visit puralityhealth.com/drshawn and use code DRSHAWN for exclusive savings.

Medical Disclaimer This podcast and website represent the opinions of Dr. Shawn Tassone and his guests. The content here should not be taken as medical advice and is for informational purposes only. Because each person is so unique, please consult your health care professional for any medical questions.