September 23, 2025

277. New Science on Fatigue Resistance, Leadville 100 Documentary, Our Fears About The Enhanced Games, A Cross Training Guide, and Timing of Strides!

1 hour 38 minutes

We had such a blast recording this great episode! The main science topic was a new study on improving fatigue resistance, which performance-matched athletes with different training approaches to see what led to better outcomes.

The conclusion is a direct prescription for athletes looking to have better endurance. Being who we are, we throw some scientific turds in the study’s punch bowl.

We also talked about the new Leadville documentary “Nothing to Lose,” which is coming out on Thursday. Yes, there was a butt shot at mile 23. But most importantly, Director Cody Bare created a beautiful film about what happens after an athlete hits rock bottom. In other words: yes, there is emotional butt too.

And this one was full of the best topics! Other topics: Megan’s recovery lessons after the 50 miler, blood volume responses, why we love the new product “Dream Shot” so much (plus a 25% discount code), why we are so horrified by champion sprinter Fred Kerley joining the Enhanced Games, Harry Styles running an amazing sub-3 hour marathon, plus questions on post-race blues, headlamps, cross training, relationships, ethical dilemmas with bicarb responders v. non-responders, timing of strides, overcoming plateaus, rest days, and mid-run carbs for low volume training.

May all of the ways you are weird be uplifted, even when they involve sneezing and toilets for some reason (that will make sense after you listen...maybe). We love you all! HUZZAH!

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-Megan and David

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By David Roche and Megan Roche

4.8

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