Dr. Will Bulsiewicz is a board-certified gastroenterologist, three-time New York Times bestselling author, and one of the world’s leading voices on the gut microbiome. His new book, Plant Powered Plus, is about inflammation and how to reduce it by healing the gut.

In this episode, we go beyond “eat more fibre” and break down the real driver behind modern disease: chronic inflammation.

We explore why over 130 conditions — from heart disease to depression — share the same inflammatory root, how your gut controls 70% of your immune system, and why stress, trauma, loneliness, and modern living may be damaging your gut more than food alone.

Dr. B explains the gut–immune connection in simple terms, reveals what’s changed in the last 125 years, and shares the daily habits that genuinely lower inflammation — including fibre, polyphenols, fermented foods, omega-3s, and even forgiveness.

If you care about energy, resilience, mental clarity, and long-term health — this episode is essential listening.

Timestamps:

00:00 – Dr Will Bulsiewicz’s journey from gut health to inflammation

00:50 – The inflammation crisis & 130+ diseases

04:15 – Is inflammation a cause or consequence?

08:44 – The gut–immune triangle explained

12:05 – Why your gut is your first line of defence

16:55 – Acute vs chronic inflammation

18:30 – Why medicine focuses on organs

21:39 – How modern medicine became symptom-focused

24:46 – Why 70% of the immune system lives in the gut

27:00 – Your microbiome tells the story of your life

28:46 – What’s really driving inflammation today

33:55 – Science vs “holistic health”

37:48 – The mind–body connection (mechanisms)

39:55 – How trauma affects the brain & body

42:10 – Stress, CRH & the gut barrier

45:37 – Chronic stress & inflammation

46:45 – Why stress disrupts digestion

48:28 – The patient who healed by quitting her job

49:04 – Sympathetic vs parasympathetic states

50:04 – What changed in the last 125 years

52:30 – Loneliness, safety & health

54:39 – Loneliness vs smoking (health impact)

55:43 – What you can practically do

56:10 – Fibre & short-chain fatty acids

58:17 – Polyphenols & colourful foods

1:00:51 – Healthy fats & omega-3s

1:02:00 – Fermented foods & inflammation

1:03:51 – The 15-minute morning routine

1:05:00 – Forgiveness, stress & healing

1:07:04 – Closing thoughtsConnect with us:

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