If you’re in midlife and feeling mentally stretched with brain fog, poor sleep or constant stress, this episode will help you understand what’s really happening.
In this episode, I’m joined by neuroscientist Dr. Tommy Wood to explore how stress, hormones, recovery and lifestyle shape your brain after 40 and what actually makes a difference.
This is a clear, practical conversation for women who want to protect their focus, memory and long-term brain health.
• What a “healthy brain” actually means in real life
• Why lack of control drives burnout
• How high-demand jobs affect dementia risk differently depending on control
• Why education and cognitive stimulation protect against decline
• What really happens to the brain during perimenopause
• The link between vasomotor symptoms, sleep and brain fog
• How creatine supports brain energetics (and dosing guidelines)
• Why leg strength predicts processing speed and dementia risk
• How sleep clears metabolic waste from the brain
• Why improving one habit can improve multiple brain pathways
00:00 Intro Stress, Burnout & Recovery: Why Your Brain Needs Rest to Adapt
01:22 What Defines a Healthy Brain?
03:10 The Demands on the Midlife Female Brain
08:00 Why Lack of Control (Not Just Stress) Increases Dementia Risk
10:34 Can You Improve Brain Function Later in Life? Neuroplasticity Explained
17:15 Decision Fatigue & Cognitive Load: The Hidden Brain Tax on Women
20:47 Brain Fog in Perimenopause: Hormones, Sleep & Cognitive Changes
27:34 Nutrient Deficiencies That Affect Brain Function (Iron, Vitamin D & B Vitamins)
28:55 Creatine for Brain Health: Memory, Depression & Cognitive Performance
37:19 Depression & Dementia Risk: What the Research Shows
39:53 Leg Strength & Brain Health: Why Lower Body Power Predicts Cognitive Function
46:32 Exercise After Poor Sleep: Why HIIT Can Restore Focus
50:19 The Glymphatic System: How Sleep Cleans the Brain
56:04 The “One Domino” Habit That Improves Brain Health
• Take the BioSyncing Quiz to help you understand what’s actually happening in your body — and how to fix it.
👉 https://biosyncing.scoreapp.com/
A BIG thank you to our sponsors who make the show possible:
• Stride - Find out your biological age and how your daily habits are influencing it with DNA, bloodwork and microbiome testing with a Stride One membership
👉 https://www.getstride.com/angela/ for 10% off
Tommy Wood, PhD, is a neuroscientist and athletic performance coach. He is a host of the “Better Brain Fitness” podcast and author of “The Stimulated Mind: Future-Proof Your Brain from Dementia and Stay Sharp at Any Age,” which will be released March 24 and is available for preorder now.
Website: https://www.drtommywood.com/
Instagram: https://www.instagram.com/drtommywood/
Podcast: https://www.betterbrain.fitness/
Book: https://www.drtommywood.com/stimulated-mind