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In this episode of the Joy Lab podcast, we're diving into the science and soul of 5-hydroxytryptophan (5-HTP), a supplement known for supporting mood through its role in serotonin production. We'll cover the basics of 5-HTP and its role in depression and anxiety along with the complex nature of depression and how 5-HTP might play a role in supporting mood (yeah, we'll even touch on the controversial serotonin hypothesis- we see you psychology and biology nerds!) Of course, since many of us want to know if supplementing with 5-HTP is helpful, we'll talk about the importance of quality in supplements, potential risks of serotonin syndrome, common 5-HTP dosages, and the nuanced approach needed when considering 5-HTP as part of mental health support.
Joy Lab and Natural Mental Health are community-supported. When you buy through the links below, we may earn a commission. That support helps keeps the Joy Lab podcast free for all!
Sources & Notes:
Full transcript here.
This content is for informational and educational purposes only. It is not intended to provide medical advice and is not a replacement for advice and treatment from a medical professional. Consult your doctor or other qualified health professional before beginning any diet change, supplement, or lifestyle program.See our terms for more information.
If you or someone you know is struggling or in crisis, help is available. Call the NAMI HelpLine: 1-800-950-6264 available Monday through Friday, 10 a.m. – 10 p.m., ET. OR text "HelpLine" to 62640 or email NAMI at [email protected]. Visit NAMI for more. You can also call or text SAMHSA at 988 or chat 988lifeline.org.
By Henry Emmons, MD and Aimee Prasek, PhD4.9
135135 ratings
In this episode of the Joy Lab podcast, we're diving into the science and soul of 5-hydroxytryptophan (5-HTP), a supplement known for supporting mood through its role in serotonin production. We'll cover the basics of 5-HTP and its role in depression and anxiety along with the complex nature of depression and how 5-HTP might play a role in supporting mood (yeah, we'll even touch on the controversial serotonin hypothesis- we see you psychology and biology nerds!) Of course, since many of us want to know if supplementing with 5-HTP is helpful, we'll talk about the importance of quality in supplements, potential risks of serotonin syndrome, common 5-HTP dosages, and the nuanced approach needed when considering 5-HTP as part of mental health support.
Joy Lab and Natural Mental Health are community-supported. When you buy through the links below, we may earn a commission. That support helps keeps the Joy Lab podcast free for all!
Sources & Notes:
Full transcript here.
This content is for informational and educational purposes only. It is not intended to provide medical advice and is not a replacement for advice and treatment from a medical professional. Consult your doctor or other qualified health professional before beginning any diet change, supplement, or lifestyle program.See our terms for more information.
If you or someone you know is struggling or in crisis, help is available. Call the NAMI HelpLine: 1-800-950-6264 available Monday through Friday, 10 a.m. – 10 p.m., ET. OR text "HelpLine" to 62640 or email NAMI at [email protected]. Visit NAMI for more. You can also call or text SAMHSA at 988 or chat 988lifeline.org.

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