In this episode, the discussion turns to a deceptively simple question that sits at the centre of countless nutrition debates: how much protein do we actually need?

On one side, there are confident claims that very high protein intakes are not just beneficial but essential for maximising strength, performance, and muscle mass. On the other, equally strong assertions that the current RDA is entirely sufficient for most people, and that going beyond it is unnecessary or even harmful.

Dr. Eric Helms and Dr. Matthew Nagra work through what the evidence actually tells us when we step away from slogans and thresholds. What does 0.8 g/kg represent, and just as importantly, what does it not? At what point do higher intakes stop meaningfully improving muscle-related outcomes? And where do concerns about kidney function, longevity, and chronic disease fit when we look at long-term data rather than isolated mechanisms?

Rather than treating protein as a single number to defend or dismiss, this conversation places intake in context: training status, ageing, health outcomes, source and optimising for specific goals.

Timestamps

• [05:19] Discussion starts
• [07:18] Setting the scene: protein intake and health
• [09:38] Health outcomes and protein intake
• [10:27] Mechanistic measures vs. longitudinal outcomes
• [15:47] The RDA: purpose and limitations
• [19:19] Higher protein recommendations: where do they come from?
• [21:48] Protein intake for athletes and general population
• [27:25] Dose response and optimal protein intake
• [44:59] Statistical errors in Morton meta-analysis
• [46:07] Comparing meta-analyses: Morton, Tagawa, and Nunez
• [56:23] Mechanistic claims and protein intake
• [59:49] Nitrogen balance and protein requirements
• [01:11:55] Protein sources and health outcomes
• [01:18:13] Summarizing optimal protein intake
• [01:24:31] Key ideas segment (premium subscribers only)

Related Resources

• Go to the episode page (with linked studies & resources)
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• Subscribe to Sigma Nutrition Premium
• Enroll in the next cohort of our Applied Nutrition Literacy course
• Dr. Helms:
  • MASS Research Review
  • Muscle & Strength Pyramids books
  • Instagram: @helms3dmj
• Dr. Nagra:
  • Instagram: @dr.matthewnagra
  • Dr. Nagra's website