Medication interactions can pose a significant health risk. Identifying and understanding the degree of interaction and appropriate management allows for optimization of care while minimizing risk. In this interview, Glenn A. Hirsch, Barbara Wiggins, and Henry D. Huang discuss drug-drug interactions of concern in contemporary cardiovascular care.

What is the optimal therapeutic strategy in non-ST-segment elevation acute coronary syndromes (NSTE-ACS) in patients not pretreated with P2Y12 adenosine diphosphate receptor antagonists, and why reduce the time to invasive strategy in NSTE-ACS? In this interview, John Gorcsan, Laurent Bonello, and Arjun Majithia discuss the EARLY trial (Optimal Timing of Intervention in NSTE-ACS Without Pre-Treatment).

Clinicians must understand the appropriate role of catheter ablation in clinical practice. In this episode, A. John Camm moderates a debate between Douglas L. Packer and Peter R. Kowey about whether ablation is still the salvation in the post-CABANA era.

The coronavirus disease 2019 (COVID-19) pandemic has profoundly changed health care delivery worldwide. In this interview, Joseph Marine, Ty Gluckman, and Yuvraj Chowdhury discuss “Case Rates, Treatment Approaches, and Outcomes in Acute Myocardial Infarction During the Coronavirus Disease 2019 Pandemic.” This study adds to the growing body of literature that has noted worsened outcomes among those with non-communicable (non-infectious) diseases during the pandemic. It also reinforces that although social distancing with COVID-19 is recommended, medical distancing is not (#StopMedicalDistancing).

Chest pain is common, and there is no agreement on how best to approach it. In this interview, Michelle O’Donoghue, Pamela Douglas, and Shashank Sinha discuss whether computed tomography angiography or stress test is the best diagnostic for chest pain.

In this interview, Freek Verheugt and Paulus Kirchhof discuss EAST-AFNET 4: Effects of Early Rhythm Control Therapy in Patients with Atrial Fibrillation from ESC Congress 2020. The results of EAST-AFNET 4 could redefine the role of rhythm control therapy for improved outcomes in patients with early atrial fibrillation.

Flu prevention with appropriate use of the influenza vaccine is more important than ever.

In this interview, Matthew Martinez, Nihar Desai, and Michelle Kelsey discuss flu shots and cardiovascular disease prevention for Fall 2020. Does coronavirus alter anything?

In this interview, Alison Bailey, Xiaowen “Wendy” Wang, and Matt Cavender discuss the importance of masking in the COVID-19 era.

In this interview, Mario Gaudino, Gregg Stone, and Deepak Bhatt discuss left main revascularization and scientific issues for optimal patient care decisions.

In this interview, Alison Bailey and Javed Butler discuss new treatments for an old disease: SGLT2 inhibitors in heart failure.