BBC Inside Science

Alzheimer's disease is becoming increasingly common as the global population ages. It is estimated that currently 44 million victims of Alzheimer's dementia exist in the world and that this will grow to more than 100 million cases by 2050. The announcement this week of the creation of the Drug Discovery Alliance - a network of labs to fast track dementia treatment aims to address the urgent need to identify drugs that prevent, slow the progression, or improve the symptoms of Alzheimer's. But what are the scientific hurdles and what's missing in our knowledge in fuelling an ambition to achieve a disease modifying therapy for dementia? Adam Rutherford speaks to Cambridge University neuroscientist Rick Livesey, and to Eric Karran, Director of Research at Alzheimer's UK

How is it possible to remember something initially and then change your account of the experience later on? Possibly, giant swathes of your own personal history are partially fictional if not completely false. The problem isn't that our memory is bad, but that we believe it isn't. Adam talks to forensic psychologist Julia Shaw whose astonishing new research examines the ability to implant completely made-up rich false memories into ordinary people in a lab setting and points to circumstances under which police officers can extract false confessions.

There's a visit to the UK's synchrotron light source at Harwell in Oxfordshire which since it started operations in 2007 has illuminating research on subjects ranging from Egyptology to virology and this year is opening its doors to the public

Adam meets Mark Kelly, one of NASA's twin astronauts taking part in a year-long space experiment to examine the impact of space travel using identical twins as subjects. With one twin orbiting on the International Space Station whilst the other remains confined to Earth, the aim is to examine how individuals with the same genetic profile respond to radically different environments - in particular the genomics of humans as they prepare to move away from their home planet.

Producer: Adrian Washbourne.

Adam Rutherford explores new insights into what lies at the very centre of the Earth. New research from China and the US suggests that the innermost core of our planet, far from being a homogenous iron structure has another, distinct region at its centre. He talks to the study's lead researcher Xiangdong Song and to geophysicist Simon Redfern about what this inner-inner core could tell us about the very long history of the Earth and the long suspected swings in the earth's magnetic field.

Professor Andrea Sella, from University College London is a recipient of the Royal Society's Michael Faraday Prize, in recognition, like Faraday himself, of exemplary science communication to the lay public. Andrea gave his prize lecture this week, describing chemistry as one of the 'crowning intellectual achievements of our age'. How justified is the claim? What have chemists ever done for us?

The sea forms the basis of ecosystems and industries, and so even subtle changes to the waters could have serious knock on effects. Dr Susan Fitzer from the University of Glasgow has been wading into Scottish lochs to study shelled creatures; they form a vital basis for marine ecosystems and the global food industry. But what effects could ocean acidification have on this vital organism?

And to mark Darwin Day Adam Rutherford examines the origins of Creationism and its most recent variation Intelligent Design. Why do opinion polls in the US routinely find that about half of the population denies the truth of Darwin's theory and believes instead that humans were created supernaturally by God at some point within the last few thousand years? He hears from historian Thomas Dixon, and from Eugenie Scott, former director of the National Centre for Science Education - a US organisation committed to keeping evolution (and now climate change) in the US schools' curriculum.

Producer: Adrian Washbourne.

As Helen MacDonald's "H is for Hawk" secures 2014's Book of the Year at the Costa Awards, a paper appears describing the hunting tactics of the Northern Goshawk, quite literally, from a birds' eye view. Suzanne Amador Kane of Haverford College in the US describes her work analyzing footage from tiny cameras mounted on the head of the predatory raptor.

The Planck Consortium releases yet more findings from the very beginning of the universe. A new age for the very first stars confirms our best models of the universe. But analysis of the dust in our own galaxy edges out the possibility that last year's BICEP2 announcement did in fact represent evidence of inflation and the first observed primordial gravitational waves.

And in the last two weeks, two giants of the twentieth century passed away. Science writer Philip Ball shares his thoughts on the lives of Carl Djerassi, father (he preferred mother) of the contraceptive pill, and Charles Townes, known as father of the Laser.

Producer Alex Mansfield.

We all remember the floods across much of central and southern England this time last year, and the devastating effect they had on people's lives and livelihoods. Today, a group of researchers at Cardiff University published a report on how people's perception of climate change has evolved in the wake of the floods. To what extent has our belief in man-made climate change altered? Do we now regard last year's events as a sign of things to come? Adam Rutherford talks to Nick Pidgeon from Cardiff University's School of Psychology who led this UK wide study

Earlier this week an international group of climate scientists, geographers and ecologists met at the Stockholm Resilience Centre in Sweden to wrangle how we can practically make the best of the Anthropocene - the new geological epoch that many consider that we now find ourselves in. Gaia Vince author of Adventures in the Anthropocene, reports from the Stockholm meeting

At the UK's Satellite Application Catapult in Harwell, a project has been unveiled that seeks to offer real time data on the world's fishing fleet to help governments police illegal fishing.

How complex cells evolved is a mystery. Current theories on the evolutionary jump, between 1 and 2 billion years ago, from life forms based on a simple prokaryote cell to the complex multiple eukaryote cells with a cell nucleus and a host of complex internal machinery, fails to explain much of what we see within animal, plant and fungi cells today. Adam talks to Buzz Baum a cell biologist at University College London who has devised a new testable model which appears to explain one of biology's most basic questions.

Producer: Adrian Washbourne.

It is likely that scientists will soon engineer strains of "friendly" bacteria which are genetically recoded to be better than the ones we currently use in food production. The sorts of bacteria we use in cheese or yoghurt could soon be made to be resistant to all viruses, for example.

Researchers writing in the Journal Nature propose this week a mechanism by which GMO's could be made to be dependent on substances that do not occur in nature. That way, if they escaped, they would perish and die.

George Church, of Harvard Medical School, tells Adam Rutherford about the way bacteria - and possibly eventually plant and animal cells - could be engineered to have such a "failsafe" included, thus allowing us to deploy GM in a range of applications outside of high security laboratories.

Adam reports from this week's launch in Paris of the International Year of Light marking 100 years since Einstein's Theory of General Relativity. Amongst the cultural and scientific events at UNESCO in Paris, Nobel Prize winner Bill Philips explains how using lasers can achieve the most accurate atomic clocks imaginable and we hear how Google X is embracing new ways to manipulate light to ignite some of the team's futuristic technologies

And as the global decline in coral reefs continues as a result of human activity, Adam talks to Hawaii based biologist Mary Hagedorn who is using unusual techniques normally adopted for fertility clinics, to store and regrow coral species that are in danger

Producer: Adrian Washbourne.

This year is the Food and Agriculture Organisation's International Year of Soils.

Adam Rutherford, ably assisted by Manchester University's Richard Bardgett, takes a look at new research seeking to further our understanding of soil behaviour that determines much of our existence.

A handful of soil contains many tens of thousands of different species of microbial life, all competing to the death with each other for nutrients and resources. Yet most of those species are very poorly understood, because hitherto scientists have only been able to grow a small percentage of them in the lab.

Last week's announcement of a new class of antibiotic - teixobactin - owes a lot to soil; Two buckets of it from the back garden of one of the researchers.

Kim Lewis of Northeastern University in the US describes the new technique that could open up the whole biodiversity of a clump of soil to future medicines.

Meanwhile, Monsanto, Novozyme and Morrone Bio in the US are just some of the big agricultural corporations exploring what useful microbes could be spread on seeds and crops to increase yields and reduce the needs for fertilizers.

Soils, apart from feeding us and helping us fight disease, also have a crucial regulatory role in our climate.

Sue Nelson reports on a new soil moisture monitoring network being set up in the UK that uses cosmic rays to measure the water content. The Cosmic-ray Soil Moisture Observing System, COSMOS-UK, is being set up by the CEH, based out of Edinburgh.

On a global scale, soils are a hugely important reservoir of carbon. Iain Hartley of the University of Exeter talks about the vast amounts of carbon - more than all the carbon in all the trees and air - held in frozen soils in the far northern reaches of the earth. If these vast plains of permafrost were to melt in a warming world, the positive feedback loop caused by the resulting methane and CO2 released could be a bigger problem than many of our climate models allow for.

But could we manage the soils beneath our feet better?

David Manning of Newcastle University suggests that minerals could be added to brownfield (urban) soils to help them capture and sequester staggering amounts of CO2 from the air to help us offset anthropogenic emissions.

Producer Adrian Washbourne.

Adam Rutherford investigates the news in science and science in the news.

This week's announcement of the discovery of 8 planets lying within the habitable zones of their stars has again raised the prospect of an earth like planet existing outside our solar system, But if we're to understand how "earth like" these exoplanets really are, we need to gain vital clues from earth's "evil twin" Venus argues environmental engineer Richard Ghail. Adam Rutherford hears about his proposed new mission to Venus - a planet orbiter to examine the surface and atmosphere that will allow us to understand why Venus has evolved so differently from earth despite their apparent sisterlike characteristics

In the more immediate future science correspondent Jonathan Amos looks ahead to some of the highlights in astronomy and physics we can expect in 2015 - from the switch on of the newly energised Large Hadron Collider, and the imminent results of the successful Rosetta mission to the comet 67P, to the long awaited flyby this summer to capture images of Pluto.

Roland Pease reports on a revolutionary method of controlling microscopic objects using sonics. As we move further into nanoscale technologies - electronic, mechanical and biological, and often a combination of all three - this could potentially offer a solution to manipulating structures, many of which are quite fragile at this scale.

And ten years on from the shock of the South East Asian Tsunami that was to cost the lives of over 220 000 people Adam Rutherford speaks to Dave Tappin of the British Geological Survey, one of the first marine geologists who went to assess the cause of this seismic event. What have we learned in the intervening years?

Producer Adrian Washbourne.

Adam Rutherford and guests oceanographer Dr Helen Czerski, cosmologist Dr Andrew Pontzen and zoologist Dr Tim Cockerill answer the listeners' science questions.

Producer: Adrian Washbourne.

Microplastics

Marine debris, mostly consisting of plastic, is a global problem, negatively impacting wildlife, tourism and shipping. However, despite the durability of plastic, and the exponential increase in its production, there was a considerable proportion of the manufactured plastic that was unaccounted for. But now scientists have found that deep-sea sediments are a likely sink for microplastics.

Holey Ice

Overeating

Vesalius

Producer: Fiona Roberts.

Where does the Earth's water come from? It's thought that it arrived from space, carried by comets. But recent research suggests otherwise. Professor Katrin Altwegg is principal investigator in charge of Rosina - the tool on the recent Rosetta mission that is charged with answering this mystery.

DNA can survive a trip into space, according to a recent experiment. Dr Lewis Dartnell, an astrobiologist from Leicester University, explains the implications.

What sounds do the oceans make? Anand Jagatia reports. Dr Julius Piercy from the University of Essex listens to coral reefs. And his recent work could help us harness sounds to help restore damaged and dying coral reefs.

This week, the new Nobel laureates head to Stockholm to pick up their medals. Among them is Norwegian neuroscientist Professor May-Britt Moser. The question on nobody's lips; what was she wearing? Which is a shame because she wore a Matthew Hubble dress featuring Grid Cells - our brain's positioning system. Discovering these grid cells won May Britt her Nobel prize. Polymer scientist Professor Tony Ryan from University of Sheffield talks fashion and science with Adam Rutherford.

Producer: Beth Eastwood.