The most played episodes among Podcast App listeners.

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   Number 1: 863: Turning Back Time: The Secrets Behind Anti-Aging Skincare

   Wrinkles, Aging, and Youthfulness - In the quest for youthful, radiant skin, a range of cutting-edge treatments and therapies has emerged to combat the signs of aging. From lymphatic massage, which aids in detoxification and reducing inflammation, to LED therapy that stimulates collagen production and reduces fine lines, and finally, PRP treatments with microneedling to enhance skin texture and elasticity — these innovative approaches offer promising solutions for those seeking to turn back the clock on aging skin. Join us as we delve into the science behind these treatments and discover how they can help you achieve a more youthful and vibrant appearance.

   September 04, 2026·17min
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   Number 2: 862: Reversing Cellular Senescence: GPX4, Ferroptosis, and Adaptive Senotherapeutics with Dr. Frederick Beddingfield

   Are you fascinated by the molecular science of aging and senescence? In this episode of Beauty Bytes, I am joined by Dr. Frederick Beddingfield III, the CEO of Rubedo Life Sciences, a physician-scientist, and a former senior leader at Allergan. We focus on the cutting edge of longevity and how Rubedo is developing adaptive senotherapeutics to reverse cellular aging and extend healthspan. Dr. Beddingfield explains the science behind their lead drug, RLS 1496, which targets the enzyme glutathione peroxidase 4 (GPX4) to regulate ferroptosis, an iron-dependent cell death pathway. We discuss how this drug not only eliminates toxic senescent cells but also acts as a "redox reset" for aged cells, reducing their biological age by improving mitochondrial function and autophagy. We also explore their groundbreaking human clinical trials, which demonstrated a 50% reduction in precancerous actinic keratoses in just four weeks without causing skin irritation. Plus, Dr. Beddingfield shares his personal biohacking stack, including low-dose rapamycin, fisetin, and quercetin. Guest Information: Dr. Frederick Beddingfield III is the CEO of Rubedo Life Sciences. You can learn more about their clinical trials at rubedolifesciences.com or follow him on Instagram and LinkedIn at @FrederickBeddingfield.

   September 02, 2026·34min
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   Number 3: 861: Melatonin 101: Anxiety, Sun Exposure, and Sleep Disorders

   Earplugs, blindfolds, or milk before bed time-if these can’t help you get a good night’s rest, you might turn to for help. But is this really the best way to solve your sleeping issues? That said, you might want to understand the mechanism behind melatonin before jumping into any impulsive decisions. Tune into this week’s Five Minutes Friday to discover the secrets behind melatonin on the market!

   August 29, 2026·12min
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   Number 4: 865: Summer Skin Recovery: Repairing Your Barrier for Fall

   Summer heat takes a toll on your skin. In this week’s podcast, we’re talking dryness, irritation, and the breakdown of your lipid barrier. This natural barrier is your shield against environmental stressors, and when it’s disrupted, inflammation follows. As the season shifts, it’s the perfect time to repair and restore. We’ll cover why ceramide-rich moisturizers matter, how hydrating soaks help replenish, and why it’s smart to ease up on exfoliation. Plus, we share tips on diet, recovery treatments, and why end-of-summer peels set you up for glowing, resilient skin heading into fall.

   September 11, 2026·12min
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   Number 5: 866: The Future of Hair: Stem Cells, Hair Cloning, and Regenerative Restoration with Dr. Richard Chaffoo

   Hair loss is more than cosmetic—it can dramatically affect confidence, identity, and how we perceive aging. In this episode of Beauty Bytes with Dr. Kay: Secrets of a Plastic Surgeon, I am joined by Dr. Richard Chaffoo, a nationally recognized triple board-certified plastic surgeon with more than 30 years of clinical experience and a special focus on hair restoration and regenerative medicine. We break down what is actually happening inside the hair follicle as hair begins to thin and why early intervention matters before chronic inflammation, miniaturization, and fibrosis permanently compromise the follicle. Dr. Chaffoo walks us through today’s treatment spectrum, from oral minoxidil and finasteride to dutasteride, PRP, microneedling, red-light therapy, and his approach to combined regenerative therapy. We also discuss why hair restoration should go beyond simply prescribing a pill or performing a transplant—and why evaluating scalp health, nutritional deficiencies, hormones, and the biological environment surrounding the follicle is so important. Then we dive into the future of hair science. Dr. Chaffoo shares his experience working with researchers at Stemson Therapeutics to create human hair follicles from pluripotent stem cells and successfully grow human hair in preclinical models. We discuss the possibility of hair cloning, follicle banking, regenerating the entire multicellular hair-follicle niche, and a future where patients may be able to preserve their own follicles or generate new ones rather than relying solely on a limited donor supply. Could hair transplantation eventually become obsolete? From stem-cell-derived follicles to regenerative treatments designed to rescue thinning hair before it is permanently lost, this conversation explores how rapidly the science of hair restoration is evolving—and what may be possible in the decade ahead. Guest Information: Dr. Richard Chaffoo is a triple board-certified plastic surgeon and hair restoration specialist based in Southern California. He co-leads La Jolla Plastic Surgery & Dermatology and has been actively involved in research exploring regenerative approaches to hair restoration and human hair follicle development. Learn more about his hair restoration practice at https://californiahairmd.com/ and follow him on Instagram at @drchaffoo.

   September 15, 2026·44min
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