Metabolic Matters

Beyond Genetics: How Mitochondria, Folate & the Microbiome Shape Autism w/ Dr. Richard Frye


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Episode Summary: In this deeply insightful episode, Dr. Nasha Winters is joined by renowned pediatric neurologist and researcher Dr. Richard Frye. With decades of experience and hundreds of peer-reviewed publications, Dr. Frye shares his groundbreaking work in autism spectrum disorder, particularly its links to mitochondrial dysfunction, neuroinflammation, and metabolic abnormalities.

You'll learn how Dr. Frye's clinical and lab research is reshaping the narrative around autism—from a strictly genetic and behavioral model to a more hopeful, treatable biomedical framework.

They dive into:

  • The mitochondrial abnormalities often present in children with autism

  • The role of oxidative stress, folate transport issues, and methylation

  • Why nutrition and prenatal health matter more than ever

  • How treatments like leucovorin, B12, CoQ10, and lifestyle changes can support better outcomes

  • The promising intersection of microbiome therapy, metabolic testing, and real-world clinical care

This is a must-listen for clinicians, caregivers, and anyone passionate about innovative approaches to autism care.

Guest Bio:Dr Frye is a Harvard trained Child Neurologist who received both an MD and PhD from Georgetown University. Dr. Frye is a national leader in autism spectrum disorder (ASD) research, particularly metabolic disorders, and has authored over 300 publications. He has developed the Metabolic Learning Resource which has recently released The Folate Fix. He is President and Chief Scientific Officer of the Autism Discovery and Treatment Foundation, Chief Medical Officer of the Neurological Health Foundation, Director of Research and Neurologist at the Rossignol Medical Center.


🔗 Connect with Dr. Richard Frye:

Wesbite: https://drfryemdphd.com/


Connect with Dr. Nasha & the Metabolic Terrain Institute of Health

💖 Donate to support Cancer Patient Treatment 

📖 Purchase “The Metabolic Approach to Cancer” Book

📰 Read this Blog Post: How to Find the Right Practitioner

💻Check out our virtual Metabolic Health Day space for Free Videos and Resources

🔍 Find a Practitioner or Advocate trained in the metabolic approach.

📘 Learn about the Terrain Advocate Program for allied health professionals.

🎓Explore the Integrative Metabolic Oncology Course for healthcare practitioners.

🌟 See Patient Testimonials

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Metabolic MattersBy Dr. Nasha Winters

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