Brain Inspired

BI 215 Xiao-Jing Wang: Theoretical Neuroscience Comes of Age


Listen Later

Support the show to get full episodes, full archive, and join the Discord community.

The Transmitter is an online publication that aims to deliver useful information, insights and tools to build bridges across neuroscience and advance research. Visit thetransmitter.org to explore the latest neuroscience news and perspectives, written by journalists and scientists.

Read more about our partnership.

Sign up for Brain Inspired email alerts to be notified every time a new Brain Inspired episode is released.

To explore more neuroscience news and perspectives, visit thetransmitter.org.

Xiao-Jing Wang is a Distinguished Global Professor of Neuroscience at NYU

Xiao-Jing was born and grew up in China, spent 8 years in Belgium studying theoretical physics like nonlinear dynamical systems and deterministic chaos. And as he says it, he arrived from Brussels to California as a postdoc, and in one day switched from French to English, from European to American culture, and physics to neuroscience. I know Xiao-Jing as a legend in non-human primate neurophysiology and modeling, paving the way for the rest of us to study brain activity related cognitive functions like working memory and decision-making.

He has just released his new textbook, Theoretical Neuroscience: Understanding Cognition, which covers the history and current research on modeling cognitive functions from the very simple to the very cognitive. The book is also somewhat philosophical, arguing that we need to update our approach to explaining how brains function, to go beyond Marr's levels and enter a cross-level mechanistic explanatory pursuit, which we discuss. I just learned he even cites my own PhD research, studying metacognition in nonhuman primates - so you know it's a great book. Learn more about Xiao-Jing and the book in the show notes. It was fun having one of my heroes on the podcast, and I hope you enjoy our discussion.

  • Computational Laboratory of Cortical Dynamics
  • Book: Theoretical Neuroscience: Understanding Cognition.
  • Related papers
    • Division of labor among distinct subtypes of inhibitory neurons in a cortical microcircuit of working memory.
    • Macroscopic gradients of synaptic excitation and inhibition across the neocortex.
    • Theory of the multiregional neocortex: large-scale neural dynamics and distributed cognition.
    • 0:00 - Intro

      3:08 - Why the book now?
      11:00 - Modularity in neuro vs AI
      14:01 - Working memory and modularity
      22:37 - Canonical cortical microcircuits
      25:53 - Gradient of inhibitory neurons
      27:47 - Comp neuro then and now
      45:35 - Cross-level mechanistic understanding
      1:13:38 - Bifurcation
      1:24:51 - Bifurcation and degeneracy
      1:34:02 - Control theory
      1:35:41 - Psychiatric disorders
      1:39:14 - Beyond dynamical systems
      1:43:447 - Mouse as a model
      1:48:11 - AI needs a PFC

      ...more
      View all episodesView all episodes
      Download on the App Store

      Brain InspiredBy Paul Middlebrooks

      • 4.8
      • 4.8
      • 4.8
      • 4.8
      • 4.8

      4.8

      134 ratings


      More shows like Brain Inspired

      View all
      Nature Podcast by Springer Nature Limited

      Nature Podcast

      760 Listeners

      Very Bad Wizards by Tamler Sommers & David Pizarro

      Very Bad Wizards

      2,657 Listeners

      The Quanta Podcast by Quanta Magazine

      The Quanta Podcast

      509 Listeners

      The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence) by Sam Charrington

      The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence)

      437 Listeners

      Philosophy For Our Times by IAI

      Philosophy For Our Times

      305 Listeners

      Future of Life Institute Podcast by Future of Life Institute

      Future of Life Institute Podcast

      107 Listeners

      The Good Fight by Yascha Mounk

      The Good Fight

      895 Listeners

      The Michael Shermer Show by Michael Shermer

      The Michael Shermer Show

      920 Listeners

      Big Brains by University of Chicago Podcast Network

      Big Brains

      470 Listeners

      Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas by Sean Carroll | Wondery

      Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas

      4,120 Listeners

      The Origins Podcast with Lawrence Krauss by Lawrence M. Krauss

      The Origins Podcast with Lawrence Krauss

      510 Listeners

      Machine Learning Street Talk (MLST) by Machine Learning Street Talk (MLST)

      Machine Learning Street Talk (MLST)

      91 Listeners

      Dwarkesh Podcast by Dwarkesh Patel

      Dwarkesh Podcast

      426 Listeners

      Clearer Thinking with Spencer Greenberg by Spencer Greenberg

      Clearer Thinking with Spencer Greenberg

      133 Listeners

      The Joy of Why by Steven Strogatz, Janna Levin and Quanta Magazine

      The Joy of Why

      504 Listeners