Dr. Christopher E Ramsden is a dietary researcher at the US NIH.
In April 2017, he published a re-analysis of the MN Coronary Experiment.
This was a rare dietary study, in that it was a randomized clinical trial. They controlled the diet of 9423 men and women nursing home and mental hospital patients.
Corn oil and polyunsaturated margarine were substituted for the current standards of animal fat.
Study groups did indeed have 13.8% lower cholesterol. Random probability less than 1 in 1000.
However, those in that same study group with lower cholesterol were at 22% higher risk of dying, mostly from heart attack and stroke. Random probability is also less than 1 in 1000.