This episode is brought to you by Cozy Earth, Maui Nui, iRestore, and Rula.

As our parents get older, the roles slowly shift from them taking care of us to us helping take care of them. But how do you do that in a way that feels supportive, not controlling or preachy? And beyond that, how do we help them optimize their health so they can stay strong, independent, and full of life for as long as possible?

Today on The Dhru Purohit Show, Dhru sits down with his sisters, Harshal and Kaya, to share the top seven things they’re doing to keep their parents healthy and thriving. Together, they explore the biggest mistakes people make when trying to create change in their parents’ lives and how those missteps can prevent lasting progress. They also dive into the seven strategies that made the most significant difference in their parents’ health journey, including strength training, increasing protein intake, and fostering community and a sense of belonging. Plus, they discuss the importance of mindset shifts, addressing sleep apnea, and building the simple habit of walking after meals.

In this episode, Dhru, Harshal, and Kaya dive into:

Dhru’s Intro and Background (00:00)

Biggest mistakes we make when approaching our parents (2:20)

Talking “at” versus “to” our parents (3:30)

Leading with empathy and compassion (7:30)

Making lifestyle changes fun through community (12:43)

Focusing on tiny wins instead of forcing big changes (18:48)

Movement and strength training as key components (22:28)

Changing environment and exposure (32:58)

Building meaningful connections (40:05)

Prioritizing protein for metabolic health (47:54)

Addressing sleep apnea and hearing loss (56:38)

Walking after meals as a core habit (1:04:18)

Sauna as an added bonus (1:07:58)

Final thoughts (1:11:28)

Also mentioned in this episode:

Try This: 7 Things I’m Doing To Keep My Parents Healthy As They Get Older

Levels Glucose Monitoring

This episode is brought to you by Cozy Earth, Maui Nui, iRestore, and Rula.

Right now, get 20% off your Cozy Earth sheets and sleepwear. Just head over to cozyearth.com/dhru and use code DHRUP.

Right now, Maui Nui Venison is offering my listeners a limited collection of my favorite cuts and products. Just go to mauinuivenison.com/dhru to secure your access now, but hurry, supply is limited!

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This episode is brought to you by Bon Charge and Cowboy Colostrum.

For decades, we’ve been told that cancer is mostly a genetic disease—something determined by fate or random mutations. But what if that’s only part of the story? What if, instead, cancer is deeply tied to how our cells produce and use energy?

​​Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Dr. Dominic D’Agostino. He shares how and why the ketogenic diet can be therapeutic for cancer, why maintaining optimal blood glucose levels is essential before using hyperbaric oxygen therapy, and how exercise and lean muscle mass play a powerful role in both prevention and treatment.

Dr. Dominic D’Agostino is an Assistant Professor at the University of South Florida College of Medicine, Molecular Pharmacology & Physiology, where he develops and tests metabolic therapies, including alternative energy substrates and ketogenic agents for neurological disorders, cancer, and wound healing. While studying the effects of gases on the brains of Navy SEAL divers, he developed an approach for metabolically starving cancer cells through diet and compressed oxygen, replacing chemotherapy, surgery, or radiation.

In this episode, Dhru and Dr. D’Agostino dive into:

Why a ketogenic diet can be therapeutic (2:21)

Lowering blood glucose to the optimal range (13:32)

Exploring the potential role of hyperbaric oxygen therapy in cancer care (15:44)

The role of exercise and muscle in cancer prevention (20:01)

Final thoughts and takeaways (23:18)

Also mentioned:

Full episode with Dominic D'Agostino

Try This: How Exercise Helps Fight Cancer

This episode is brought to you by Bon Charge and Cowboy Colostrum.

Right now, Bon Charge is offering my community 15% off. Just go to boncharge.com/DHRU and use code DHRU to save 15%.

Right now, Cowboy Colostrum is offering my listeners 25%. Just go to CowboyColostrum.com/DHRU and use code DHRU to save 25% today. 

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This episode is brought to you by BiOptimizers, Masa Chips, and Ollie.

Life has a way of teaching us what truly matters, but often, those lessons come too late. In this episode, we explore the timeless wisdom that comes from facing the end of life and reflecting on what’s most important.

Today on The Dhru Purohit Show, Dhru sits down with Bronnie Ware to discuss the top five regrets of the dying. Bronnie shares powerful lessons she learned from patients on their deathbeds during her years as a palliative care nurse. She talks about why it’s so difficult for many people to say no, how deeply ingrained people-pleasing can become in our identities, and the freedom that comes from slowing down in a world that glorifies constant hustle. Bronnie also explores how failing to express yourself can keep you from living the life you truly want. 

Bronnie Ware, author of the international bestselling memoir The Top Five Regrets of the Dying (published in 32 languages), is also a TEDx speaker who has been featured in interviews with The Wall Street Journal, ABC Radio National, Dr. Wayne Dyer, The Guardian, Marie Forleo, The Sunday Times, Lewis Howes, Harvard Business Review, and numerous other publications worldwide. Based in Australia, she advocates for simplicity and the importance of creating space to breathe, encouraging others to find courage, follow their hearts, and trust that life will provide the shortcuts.

In this episode, Dhru and Bronnie dive into: 

Why it’s so difficult to say no (1:53)

Permission to live a life true to yourself (6:37)

Finding the courage to slow down in our modern world (10:30)

Bronnie’s journey and how she chose to follow her passion (19:30)

Facing the pain of dying and making the most of life (24:34)

Working hard but missing out on truly living (30:00)

Dhru’s Man Morning community (36:11)

The need for control vs. the courage to let go (38:33)

Divine love as the greater intelligence guiding our lives (40:50)

Lessons from Bronnie’s time with people nearing death (46:20)

The regret of not expressing your true feelings (48:45)

Losing touch with friends and community (59:15)

Permission to be happy and feel joy (1:08:54)

Learning through mistakes and cultivating self-compassion (1:15:38)

Final thoughts and takeaways (1:19:16)

Also mentioned in this episode:

The Top Five Regrets of the Dying

For more on Bronnie, follow her on Facebook, Instagram, YouTube, or visit her Website.

This episode is brought to you by BiOptimizers, Masa Chips, and Ollie.

Go to bioptimizers.com/dhru now and enter promo code DHRU to get 30% off any order of Magenesium Breakthrough and find out this month’s gift with purchase.

Ready to enjoy my favorite chips made with just three clean ingredients? Head to masachips.com/DHRU and use code DHRU for 25% off your first order of Masa.   

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This episode is brought to you by Branch Basics, iRestore, and Rula.

Most people focus on quick fixes when it comes to losing weight, but lasting change takes more than just reducing the number on the scale. Today’s guest shares what it really takes to build sustainable habits and redefine your approach to health and fitness.

Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Adam Schafer. Adam shares the behaviors and motivations that drive long-term, sustainable change and how it all begins with a mindset shift around what fat loss should truly look like. He also dives into how unrealistic weight-loss goals can discourage real body composition change. Dhru and Adam discuss why it’s never too late to rethink your fitness goals and share personal experiences that highlight the power of improving overall metabolic health.

Adam Schafer, an IFBB pro bodybuilder and founding member of Mind Pump Media, joins us today as a co-host of the popular Mind Pump podcast. He managed some of the largest fitness clubs in the Bay Area and, along the way, collected eight national certifications, as well as a pro card in bodybuilding.

In this episode, Dhru and Adam dive into:

Motivation to change behavior patterns for sustainable change (1:39)

Mindfulness and mindset shifts that improve how you feel (7:38)

Overcoming discouragement from unrealistic goals (09:45)

Ginny MacColl, the Oldest American Ninja Warrior (18:04)

How Adam trained his wife and what she discovered (21:27)

Final thoughts and takeaways (25:21)

Also mentioned:

Full episode with Adam Schafer

10 Ways to Tackle Fat Loss Everyday Guide

This episode is brought to you by Branch Basics, iRestore, and Rula.

Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use the coupon code DHRU. Make 2025 your cleanest, healthiest year yet with Branch Basics!

Hair loss is frustrating. Give yourself the gift of hair confidence. For a limited time, my listeners get a huge discount on the iRestore Elite and irestore.com  with code DHRU. 

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This episode is brought to you by One Skin and Momentous.

Perimenopause is something nearly every woman will experience, yet many don’t recognize what’s happening until symptoms begin to disrupt daily life. This week, I asked my sisters, Kaya and Harshal, to sit down with Dr. Mariza Snyder for an open and honest conversation about perimenopause. Together, they bring personal experience and curiosity to the discussion, unpacking what’s really happening in the body during this stage and how women can navigate it with more ease and support.

Today on The Dhru Purohit Show, Kaya and Harshal sit down with Dr. Mariza Snyder to discuss the perimenopause stage of life. Dr. Mariza explains the first signs of perimenopause, which can vary widely and affect the entire body well beyond the breasts and ovaries. She breaks down what happens inside the body during this transition, how it can lead to surprising changes in daily life, and the key tests that can help women navigate this phase while protecting their brain and metabolic health. Dr. Mariza also shares why stress management, community, and movement are essential tools for empowering ourselves through this time.

Dr. Mariza Snyder is a functional practitioner, women’s hormone expert, and the author of nine best-selling women’s health books. Her newest book, The Perimenopause Revolution, breaks down the real reasons women often feel “off” in their 30s, 40s, and 50s, such as stubborn weight gain, brain fog, low energy, anxiety, and poor sleep, and provides a clear, proven roadmap to help them feel like themselves again. For over 15 years, Dr. Mariza has spoken worldwide on hormone and metabolic health, nutrition, and detoxification. She also hosts the top-rated Energized Podcast,  empowering women to become the CEO of their health.

In this episode, Kaya, Harshal, and Dr. Snyder dive into: 

Spotting the first signs of perimenopause (1:58)

Menopause as the “second puberty” (07:10)

Take the Are You in Perimenopause? quiz (09:15)

Why your brain changes during menopause (14:04)

Tackling shifting cycles & estrogen dominance (21:17)

Muscle, body composition & strength in midlife (30:56)

What to do if your metabolic markers are high (33:04)

Hormones, sleep & circadian rhythm reset (39:25)

Alcohol’s hidden impact on women’s hormones (47:01)

Stress, self-care & the power of gratitude (48:40)

The overlooked benefits of NEAT (55:46)

How to thrive through perimenopause (01:10:13)

Inside The Perimenopause Revolution (01:13:30)

Also mentioned in this episode:

The Perimenopause Revolution: Reclaim Your Hormones, Metabolism & Energy

For more on Dr. Snyder, follow her on Facebook, X/Twitter, Instagram, YouTube, Pinterest, Apple Podcasts, or visit her Website.

This episode is brought to you by One Skin and Momentous.

Right now, One Skin is offering my community 15% off; just go to oneskin.co and use the coupon code DHRU to save 15% and give your skin the scientifically proven, gentle care it deserves.

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This episode is brought to you by Pique Life and Masa Chips.

For a long time, most people thought blood sugar only mattered if you had diabetes. But we now know it influences so much more: your energy, focus, mood, and ultimately your ability to live up to your highest potential. And there’s one thing that impacts all of these more than you might realize: glucose spikes.

Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Jessie Inchauspé. Jessie shares how and why switching to a savory breakfast can alter the trajectory of your day and energy. She also shares how a glucose roller coaster can create a false sense of energy and lead to brain fog, and how movement can help combat these fluctuations. Stabilizing your blood sugar isn’t just about diet, it’s about unlocking clearer thinking, balanced energy, and a steadier mind to help you feel and perform your best every day.

Jessie Inchauspé is on a mission to translate cutting-edge science into practical tips to help people enhance their physical and mental well-being. She’s the founder of the wildly popular Instagram account GlucoseGoddess, where she teaches life-changing food habits to hundreds of thousands of people. Jessie holds a bachelor’s degree in mathematics from King’s College London and a master’s degree in biochemistry from Georgetown University. Her work at a genetic analysis start-up in Silicon Valley made her realize that, as the key to good health, food habits beat genetics. 

In this episode, Dhru and Jessie dive into:

Why a savory breakfast helps you take control of your day (2:20)

The glucose rollercoaster: false energy and brain fog (7:38)

How movement supports blood sugar control (12:23)

Muscles as allies for stable glucose and daily NEAT activity (18:00)

Final thoughts (22:17)

Also mentioned:

Full episode with Jessie Inchauspé

This episode is brought to you by Pique Life and Masa Chips.

Right now, Pique Life is offering 20% off their Daily Radiance Liposomal Vitamin C plus a free beaker and frother when you go to piquelife.com/dhru.

Ready to enjoy my favorite chips made with just three clean ingredients? Head to masachips.com/DHRU and use code DHRU for 25% off your first order. 

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This episode is brought to you by LMNT, Bon Charge, and Birch Living.

When we think of mitochondria, we often think of them as the powerhouse of the cell, but they do so much more. Mitochondria are responsible for intricate functions like detoxification, immune defense, and cell signaling. Their health is directly tied to our overall health.

Today on The Dhru Purohit Show, Dhru sits down with Dr. Daria Mochly-Rosen to discuss why protecting our mitochondria is essential for long-term health. Dr. Daria reveals the top insults that damage mitochondrial function, such as air pollution, pesticides, and chronic stress, and explains how they’re linked to conditions like Parkinson’s disease. She also shares her groundbreaking research on aldehyde dehydrogenase 2 and emphasizes why, in today’s world, our mitochondria are under constant attack, making it more important than ever to reduce these burdens on the body.

Dr. Daria Mochly-Rosen is the George D. Smith professor for translational medicine at Stanford University School of Medicine. She is passionate about turning scientific discoveries into real-world treatments and helping people make informed health choices. She has founded three biotech companies and created SPARK, a program that focuses on translating scientific innovations to benefit patients. Following the success of the program at Stanford, which led to the formation of over fifty biopharmaceutical companies, SPARK now operates in dozens of universities around the world. 

In this episode, Dhru and Dr. Rosen dive into: 

What’s really hurting your mitochondria today (1:20)

How air pollution, smoke and vaping chip away at your cells (2:40)

The hidden danger of pesticides (9:00)

Are we sensitive to electromagnetic frequencies? (17:55)

Radiation’s surprising effect on your cells (22:45)

The enzyme that could reveal your mitochondrial health (27:45)

Should you worry about everyday radiation? (36:21)

The control you do have over your health (41:51)

Light, sleep, and mitochondria: the photobiomodulation link (42:46)

Why chronic stress silently destroys mitochondria (47:16)

The connection between mitochondria and aging (51:58)

How exercise powers up your mitochondria (01:01:06)

The secret of pairing endurance with strength (1:09:15)

Fiber’s underrated role in mitochondrial health (1:14:21)

Also mentioned in this episode:

The Life Machines: How Taking Care of Your Mitochondria Can Transform Your Health

For more on Dr. Rosen, follow her on LinkedIn or visit her Website.

This episode is brought to you by LMNT, Bon Charge, and Birch Living.

Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to drinkLMNT.com/dhru today.

Right now, Bon Charge is offering my community 15% off. Just go to boncharge.com/DHRU and use code DHRU to save 15%.

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This episode is brought to you by Maui Nui and AquaTru.

Getting the right nutrients is essential. But in today’s world, more isn’t always better. From vitamins to organ meats, Chris Kresser breaks down what we actually need, what we’re missing, and where we might be overdoing it.

Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Chris Kresser. He explains how the body naturally processes nutrients from whole foods compared to the impact of over-supplementation in our modern world. Chris highlights the importance of vitamin D, K2, and magnesium, as well as the benefits of organ meats and concerns surrounding bioavailability.

Chris Kresser, M.S., L.Ac., is cofounder of the California Center for Functional Medicine, founder of the Kresser Institute, and host of the top-ranked podcast Revolution Health Radio. A New York Times bestselling author and one of the most respected voices in Functional Medicine and ancestral health, Chris has trained over 2,000 clinicians worldwide. He was named one of the 100 most influential people in health and fitness by Greatist and has appeared in major outlets like Time, The Atlantic, NPR, and Fox. 

In this episode, Dhru and Chris dive into:

Which nutrients you can get too much of (1:57)

Optimal vitamin D levels and the risks of over-supplementation (4:07)

Vitamin K2 and magnesium in conjunction with vitamin D (11:01)

Nutrient-rich organ meats and tips for adding them to your diet (12:41)

Key nutrients missing from most diets (24:06)

Calcium and bioavailability (27:29)

Final thoughts (29:59)

Also mentioned:

Full episode with Chris Kresser

Try This: 3 Overhyped Supplements—And What to Take Instead

This episode is brought to you by Mau Nui and AquaTru.

Right now, Maui Nui Venison is offering my listeners a limited collection of my favorite cuts and products. Just go to mauinuivenison.com/dhru to secure your access now, but hurry, supply is limited!

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This episode is brought to you by BiOptimizers, Cozy Earth, and Fatty15.

While the “10,000 steps a day” idea came from a marketing company in Japan, that doesn’t mean walking itself is a gimmick. Today’s guest shares why he is so passionate about walking and the research that supports this accessible habit, one that can be incorporated into most people’s lives and lead to significant results and shifts in their health and wellness journey.

Today on The Dhru Purohit Show, Dhru sits down with Greg Mushen to explore the profound benefits of walking as a fundamental aspect of health and wellness. Greg shares how walking can be more effective than medications for managing blood sugar. He explains why maintaining a high step count supports weight loss and mood regulation, and highlights the critical role walking plays in cardiovascular health. He also emphasizes the importance of fiber and potassium in the diet, the influence of genetics on health, and the benefits of personal experimentation in achieving optimal outcomes. The conversation reveals why walking, one of the most low-cost and accessible habits, could be the missing link to better health and why you’ll want to hear the data for yourself.

Greg Mushen is a health researcher, writer, and systems thinker with a long career in the tech industry. After years of building and scaling technology products, he turned his focus to one of medicine’s biggest puzzles: why subsistence populations largely avoid chronic disease. His approach combines anthropology with modern science, connecting lipid kinetics, gut microbiome ecology, and evolutionary biology into a systems-level understanding of human health. A lifelong builder, whether in startups, overland rigs, or new health frameworks, Greg now approaches human healthspan as the ultimate engineering problem: resilience, adaptability, and longevity.

In this episode, Dhru and Greg dive into: 

The importance of doubling down on walking (1:10)

Greg’s physical transformation through walking (9:31)

Combining walking with resistance training (20:26)

The link between lipid clearance, fat oxidation, and walking (26:25)

Incorporating regular movement into daily life (27:45)

Key comparisons between walking and running (34:08)

Developing an elite VO₂ max (37:47)

Vascular stiffening and endoPAT testing (41:47)

Why fiber intake matters and how Greg increases intake (44:45)

The role of genetics in cardiovascular health (58:43)

The importance of potassium in the diet (1:08:15)

Lessons from subsistence populations on chronic disease (1:14:02)

Final thoughts and key takeaways (1:15:12)

Also mentioned in this episode:

Study on the Association of Daily Step Count and Step Intensity With Mortality Among US Adults

Study on Postmeal Exercise Blunts Postprandial Glucose Excursions In People On Metformin Monotherapy

Try This: 5 Things I Changed After Getting Genetic Testing

Greg’s Chili Recipe

For more on Greg, follow him on X/Twitter, Instagram, Threads, and Substack.

This episode is brought to you by BiOptimizers, Cozy Earth, and Fatty15.

Go to bioptimizers.com/dhru now and enter promo code DHRU to get 30% off any order of Magenesium Breakthrough and find out this month’s gift with purchase.

Right now, get 20% off your Cozy Earth sheets and sleepwear. Just head over to cozyearth.com/dhru and use code DHRUP.

Fatty15 is offering an additional 15% off its 90-day subscription Starter Kit. Go to fatty15.com/dhru and use code DHRU to replenish your C15 levels for long-term health.

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This episode is brought to you by Bon Charge and AquaTru.

Dwindling memory is often seen as a normal part of aging. But just because it’s common doesn’t mean it’s normal. There’s a lot we can do to safeguard the memory center of our brain, and it’s never too late to start.

Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Dr. Majid Fotuhi. He unpacks how excess sugar from a highly refined, processed diet can accelerate aging and damage key organs, including the kidneys, liver, and brain. Dr. Fotuhi also highlights animal studies linking sugar to brain decline, the blood markers we should all be monitoring, and practical strategies to support brain growth. Finally, he shares why having a strong sense of purpose is one of the most powerful ways to protect brain health.

Dr. Fotuhi is a neurologist specializing in memory, concussion, and successful aging. With over 30 years of teaching, clinical practice, and neuroscience research at Harvard Medical School and Johns Hopkins, he has developed a multidisciplinary program to help people of all ages improve memory and attention. The results of his program have been published in numerous scientific journals as well as in his three books. Passionate about public education on brain health, Dr. Fotuhi also teaches in the Department of Psychological and Brain Sciences at George Washington University and at Harvard Medical School.

In this episode, Dhru and Dr. Fotuhi dive into:

Why sugar is so damaging to the brain (01:46)

How elevated uric acid levels accelerate brain aging (11:22)

Essential blood markers to monitor regularly (17:27)

Key strategies to support brain growth (21:24)

Why having a sense of purpose is vital for brain health (22:42)

Final thoughts (30:35)

Also mentioned:

Full episode with Dr. Majid Fotuhi

Try This: How Fructose Damages the Brain and Increases Our Risk for Alzheimer’s

This episode is brought to you by Bon Charge and AquaTru.

Right now, Bon Charge is offering my community 15% off. Just go to boncharge.com/DHRU and use code DHRU to save 15%.

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