The Dr. Gabrielle Lyon Show

Comfort is Destroying Your Health: Why Stress is Not the Enemy | Jeff Krasno


Listen Later

Jeff Krasno’s personal health transformation—reversing diabetes, shedding 60 pounds, and reclaiming his health at age 50—is a masterclass in what he calls “good stress.” In this episode, we dive into the simple but powerful idea that discomfort might just be the medicine we all need. Jeff, the founder of Commune and host of the Commune podcast, shares how fasting, cold exposure, resistance training, and attention to modern habits helped him regain his energy, build muscle, and thrive.

Together, we discuss how metabolic dysfunction has become the norm, how adaptive stress responses can be harnessed to reverse chronic illness, and why building muscle is not only the antidote to obesity but also a critical factor in longevity. If you’re interested in reclaiming your vitality and learning how to work with—not against—your biology, this episode will speak to you.

We cover:

  • Jeff’s story of personal health transformation at midlife
  • What “good stress” is and how to harness it to improve health
  • Why chronic ease leads to chronic disease
  • Cold therapy, fasting, and training as adaptive stressors
  • The importance of resistance training for blood sugar control
  • How metabolic dysfunction hides in plain sight
  • Practical tips to increase non-exercise activity thermogenesis (NEAT)
  • Building muscle as the path to longevity and disease prevention

Who is Jeff Krasno?

Jeff Krasno is the co-founder and CEO of Commune, a masterclass platform for personal and societal well-being. He hosts the Commune podcast, where he’s interviewed luminaries like Deepak Chopra, Gabor Maté, and Matthew McConaughey. Jeff also writes a weekly personal essay called “Commusings,” delivered to over a million subscribers every Sunday. His new project, Good Stress, is an online course, upcoming book, and developing TV series, built on the wellness strategies that helped him reclaim his health after a diabetes diagnosis. He is also the co-creator of the global wellness event series Wanderlust and was selected for Oprah’s SuperSoul100 in 2016.

This episode is brought to you by:

  • Puori – Code DRLYON for 20% off sitewide! – https://Puori.com/DRLYON
  • ARMRA – Code DRLYON for 15% off! – https://armra.com/DRLYON
  • BON CHARGE – Code DRLYON for 15% off! – https://boncharge.com/DRLYON
  • MUD\WTR – Code DRLYON for up to 43% off – http://mudwtr.com/DRLYON

Find Jeff Krasno at:

  • Website – https://www.jeffkrasno.com
  • Instagram – https://www.instagram.com/jeffkrasno
  • LinkedIn – https://www.linkedin.com/in/jeffkrasno
  • YouTube – https://www.youtube.com/@Commune
  • Good Stress (Course & Book) – https://www.goodstress.com

Find me at:

  • Instagram: @drgabriellelyon
  • TikTok: @drgabriellelyon
  • Facebook: facebook.com/doctorgabriellelyon
  • YouTube: youtube.com/@DrGabrielleLyon
  • X (Twitter): x.com/drgabriellelyon
  • Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
  • Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
  • Get my book – https://drgabriellelyon.com/forever-strong/
  • Forever Strong Summit 2025 – Grab your ticket NOW before we sell out! https://drgabriellelyon.com/forever-strong-summit-2025/

Timestamps:

00:00 – Intro & Forever Strong Summit Announcement

02:07 – Meet Jeff Krasno

03:26 – Chronic ease and the rise of chronic disease

05:55 – Adaptive stress responses: why we evolved to need discomfort

07:19 – The comfort traps of modern life

08:24 – Sedentary lifestyles and metabolic consequences

10:10 – Stress, cortisol, and modern triggers

14:05 – What is “good stress”?

15:00 – Jeff’s health breakdown and the first signs of metabolic dysfunction

17:32 – Using a CGM to detect prediabetes

19:25 – The shocking blood sugar results

20:31 – Spiritual and cultural influences on Jeff’s diet

23:37 – How Jeff’s body composition changed

24:44 – The shift to a ketotarian diet

30:09 – Fasting, ketones, and metabolic flexibility

32:55 – Intermittent fasting and circadian biology

35:14 – The combination that moved the needle: fasting + cold exposure

41:21 – Cold plunges and thermogenesis

44:39 – Why cold stress melts fat

48:06 – The motivation behind embracing discomfort

52:00 – Building muscle: the final frontier of Jeff’s transformation

53:27 – Resistance training for metabolic health

54:45 – The trap of “chronic cardio”

57:14 – The difference between losing fat and building muscle

59:23 – How Jeff learned the science through self-experimentation

1:01:01 – From bodyweight training to pull-ups and gym sessions

1:04:28 – Why resistance training finally clicked for Jeff

1:07:47 – Jeff’s recommendations: move more, lift often, live intentionally

1:11:45 – NEAT: the underrated tool for metabolic health

1:12:56 – Jeff’s final thoughts: redefining ease and fulfillment

Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

...more
View all episodesView all episodes
Download on the App Store

The Dr. Gabrielle Lyon ShowBy Dr. Gabrielle Lyon

  • 4.6
  • 4.6
  • 4.6
  • 4.6
  • 4.6

4.6

886 ratings


More shows like The Dr. Gabrielle Lyon Show

View all
The Human Upgrade with Dave Asprey by Dave Asprey

The Human Upgrade with Dave Asprey

7,160 Listeners

The Model Health Show by Shawn Stevenson

The Model Health Show

7,378 Listeners

FoundMyFitness by Rhonda Patrick, Ph.D.

FoundMyFitness

5,239 Listeners

High Intensity Health with Mike Mutzel, MS by Author Mike Mutzel interviews Jeff Bland, Datis Kharrazian, Ben Greenfield, Abel James, Dave Asprey, Ben Lynch, Jade Teta and Corey chuler

High Intensity Health with Mike Mutzel, MS

1,224 Listeners

Well Beyond 40 by JJ Virgin

Well Beyond 40

1,087 Listeners

Mind Pump: Raw Fitness Truth by Sal Di Stefano, Adam Schafer, Justin Andrews, Doug Egge

Mind Pump: Raw Fitness Truth

11,643 Listeners

Optimal Protein Podcast with Vanessa Spina by Vanessa Spina

Optimal Protein Podcast with Vanessa Spina

767 Listeners

The Genius Life by Max Lugavere

The Genius Life

4,830 Listeners

Dhru Purohit Show by Dhru Purohit

Dhru Purohit Show

3,466 Listeners

The Dr. Hyman Show by Dr. Mark Hyman

The Dr. Hyman Show

9,198 Listeners

The Peter Attia Drive by Peter Attia, MD

The Peter Attia Drive

7,767 Listeners

Everyday Wellness with Cynthia Thurlow ™ by Everyday Wellness™

Everyday Wellness with Cynthia Thurlow ™

1,172 Listeners

Better! with Dr. Stephanie by Dr. Stephanie Estima

Better! with Dr. Stephanie

576 Listeners

Huberman Lab by Scicomm Media

Huberman Lab

28,143 Listeners

Perform with Dr. Andy Galpin by Scicomm Media

Perform with Dr. Andy Galpin

1,141 Listeners