In this episode, Dr. Brandon and Dr. Morgentaler talk about how emerging research suggests testosterone therapy may not only be safe but could actually help protect against aggressive prostate cancer, while also touching on practical approaches to maintaining sexual connection at midlife. 00:34 Addressing Listener Questions on Sexual Connection – Dr. Brandon and Dr. Morgentaler discuss practical, therapist-friendly strategies for couples looking to gently reboot intimacy and improve sexual connection at midlife. 04:17 Introduction to Testosterone and Prostate Cancer – The hosts introduce the question of whether testosterone therapy could be protective against prostate cancer, setting the stage for reviewing the latest evidence. 05:06 Historical Perspective on Testosterone Therapy – They review the decades-long belief that testosterone increases prostate cancer risk and explain how this view limited therapy use until more recent decades. 08:15 Recent Research and Findings – They highlight large observational studies and randomized trials showing that testosterone therapy is not linked to higher prostate cancer risk and may even reduce aggressive cancer incidence. 16:26 Concluding Thoughts and Future Directions – The hosts emphasize the need for future randomized trials and discuss how these findings are shifting perspectives on testosterone therapy for men's health. Resources: Loeb, S., Berglund, A., & Stattin, P. (2013). Population based study of use and determinants of active surveillance and watchful waiting for low and intermediate risk prostate cancer. The Journal of Urology, 190(5), 1742–1749. https://doi.org/10.1016/j.juro.2013.05.054 ____ By the way, if you want to learn directly from leaders like Dr. Abrahama Morgentaler, Mohit Khera, and Rachel Rubin, this is your chance. We'll be diving deep into the science, the evidence, and the clinical realities of testosterone therapy. Join us in Orlando on January 16–17, 2026, or attend via livestream. You can register now at HMSTestosteroneCourse.com With Dr. Abraham Morgentaler and Dr. Marianne Brandon Listen to the podcast on all of your favorite platforms: Apple: https://podcasts.apple.com/ec/podcast/the-sex-doctors/id1761813985?l=en-GB Spotify: https://open.spotify.com/show/0apSFzquJXKoOGnmI6ndgT?si=e5a1e482c7ca46c7 Find us on: Instagram: https://www.instagram.com/thesexdoctors?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw== Facebook: https://www.facebook.com/thesexdoctors YouTube: https://www.youtube.com/@thesexdoctorspod TikTok: https://www.tiktok.com/@thesexdoctor LinkedIn (Dr. Abraham): https://www.linkedin.com/in/abraham-morgentaler-md-81628b6 LinkedIn (Dr. Marianne): https://www.linkedin.com/in/mariannebrandon-59224513 X (Dr. Abraham): https://x.com/DrMorgentaler X (Dr. Marianne): https://x.com/drbrandon #TestosteroneTherapy #ProstateCancerResearch #HormoneHealth