Dr Karan Explores

Do Your Genes Make You Fat? With Dr Giles Yeo


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šŸ’¬ ā€œPeople think I’m anti-physics. I’m not anti-physics. Calories don’t give you the information to improve your diet.ā€

āš”ļø Dr Giles Yeo is a geneticist at Cambridge University specialising in obesity and how our brain controls food intake. He’s also the author of ā€˜Why Calories Don't Count’ and ā€˜Gene Eating’.

āš”ļø In this episode Giles and I dig into the science of genetics and hunger hormones and why some people struggle with their weight more than others. I also challenge him on the notion that calories don’t count.

šŸŽ§ Stay tuned to find out:

āž”ļøŽ How over 1000 genes are involved in body weight and controlling your appetite

āž”ļøŽ Why obesity isn’t a moral failing and should be thought of as a disease

āž” The huge variety in how different ethnicities are impacted by obesity

āž”ļøŽ What exactly ā€œcalories don’t countā€ really means

āž”ļøŽ Why fad diets should be ignored and how to find the diet that works for YOU

šŸ“• Chapters

(1:29) Obesity is not a moral failing

(4:01) Is obesity a disease?

(6:00) The role of genetics

(8:39) Obesity phenotypes

(10:59) Best diet for weight loss?

(13:14) Where’s the data coming from?

(15:44) How different ethnicities are affected by obesity

(20:02) Calories don’t count?

(24:34) The truth about ozempic

(26:49) Hungry hormones

(30:11) Not all calories are the same

(32:09) How poverty affects obesity

(34:14) Environment v genetics

(36:19) Reframe the blame

(39:16) Do we need policy change?

(43:18) Our outdated biology

(49:04) Does taste affect weight gain?

(53:59) The microbiome

(58:07) How to take action

šŸ“± Connect with me:

TikTok: https://www.instagram.com/drkaranrajan

Instagram: https://www.tiktok.com/@dr.karanr

šŸ“± Connect with Giles:

Instagram: https://www.instagram.com/gilesyeo/

X: https://x.com/GilesYeoĀ 

šŸ“• Grab Giles’ book here: https://amzn.eu/d/hoAnVLrĀ 

šŸ”„ For more useful science for your everyday life, grab my best selling book ā€œThis Book May Save Your Lifeā€: https://geni.us/DrKaranBookĀ 

šŸŽ™ļø An OG Podcasts production.

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