💬 If you improve your foot health and strength, you’ll not only fix back pain and bunions - you’ll increase your lifespan and improve your brain health!

⚡Most of us ignore our feet, squishing them into tight, cushioned shoes. But weak feet can cause problems throughout the body - and fixing them is easier than you think.

Dr Courtney Conley and Dr Jenifer Perez are the founders of Gait Happens - and experts in foot health. They join Dr Karan to share the top things you should start doing now.

🎧 Stay tuned to find out:

➡ Why back, hip and knee pain so often starts at the feet

➡︎ How to undo the damage of bunions and plantar fasciitis

➡︎ Why flat feet aren’t a death sentence

➡︎ Whether barefoot shoes are really worth your money

➡︎ Simple things parents can do to protect their kid’s feet

➡︎ Training and gadgets you can use for strong feet

#DrKaran, #MedicalScience, #HealthEducation, #HealthTips, #FootHealth, #BarefootShoes, #ToeStrength, #PlantarFasciitis

Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 

📕 Chapters

(0:00) Introduction - How foot strength affects your brain, lifespan and entire body

(2:13) What you’re doing to weaken your feet

(3:09) Why foot strength becomes increasingly important beyond 50

(5:54) How to fix bunions

(7:33) Why  plantar fasciitis is so hard to get rid of

(10:38) What are the signs of a weak foot?

(14:00) How far up the chain do feet problems impact?

(16:36) Biggest mistakes people make when buying shoes

(21:50) Are barefoot/minimalist shoes worth it?

(26:36) Should you spend more time barefoot?

(28:10) Best ways to protect our children's feet

(32:32) Favourite daily foot strengthening exercises

(38:33) One thing anyone can start doing today

🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 

🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 

📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5

🔥  Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.

🎙️ An OG Podcasts production.

About Dr Karan:

Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.

📱Connect with me:

Instagram: https://www.instagram.com/drkaranrajan/   

Facebook: https://www.facebook.com/DrKaranR/  

TikTok: https://www.tiktok.com/@dr.karanr  

X: https://twitter.com/drkaranrajan  

Website: https://linktr.ee/ThisisVitalInformation

💬 Should you be taking peptides? From anti-aging promises to superhuman healing - peptides are massively hyped right now, and are being aggressively marketed online. But here’s why you should think twice before giving in to the marketing.

⚡While there are many FDA-approved peptides that you can get your hands on, most of the hype right now is focussed on grey-market, unregulated drugs. Things like BPC-157, TB-500 and the “Wolverine stack”.

In this AMA, Dr Karan answers your top questions about peptides and breaks down the real science behind the online claims.

🎧 Stay tuned to find out:

➡ What a peptide actually is - explained as simply as possible

➡︎ Whether peptides in skincare actually work - and how they differ from injectables

➡︎ If peptides can slow down aging - or help with autoimmune diseases

➡︎ Why marketing is drawing comparisons between peptides and GLP-1s

➡︎ If BPC-157 actually helps with healing and recovery - and the possible dangers

➡︎ The side effects of injecting peptides your body doesn't actually need

#PeptideTherapy, #LongevityScience, #EvidenceBasedHealth, #Biohacking, #HealthPodcast, #DrKaran, #MedicalMythsDebunked

Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 

📕 Chapters

(0:00) Introduction

(1:18) What is a peptide?

(4:11) Difference between skincare peptides and injectables

(6:03) Which peptides are FDA-approved?

(7:58) Why people compare GLP-1s with peptides

(9:22) Why isn’t the FDA cracking down on illegal sales?

(11:05) The real science of BPC-157

(12:58) Have these peptides been studied for cancer causing effects?

(15:16) Side effects of injecting peptides you don’t need

(17:04) Are the anti-aging claims really true?

(18:53) Do peptides help with autoimmune diseases?

(20:14) What is the “Wolverine stack”?

(22:03) Is there a best way to take peptides?

(23:12) Overview and summary

🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 

🤖 Discover my digital twin here: http://DrKaran.ai 

🔥  Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.

🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 

📕 Order my new book, This Is Vital Information, here: https://amzn.eu/d/0gfgOXFo

🎙️ An OG Podcasts production.

About Dr Karan:

Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.

📱Connect with me:

Instagram: https://www.instagram.com/drkaranrajan/   

Facebook: https://www.facebook.com/DrKaranR/  

TikTok: https://www.tiktok.com/@dr.karanr  

X: https://twitter.com/drkaranrajan  

Website: https://linktr.ee/ThisisVitalInformation

Prostate cancer is the most common cancer in men, but it often has no obvious symptoms.

In this episode, Dr Karan Rajan speaks with Professor Prabhakar Rajan, a urologist and prostate cancer specialist, about prostate cancer risk, PSA testing, MRI scans, treatment choices, testicular cancer, and why men often delay asking for help.

They discuss when urinary symptoms, blood in urine, persistent back pain, testicular lumps, and changes in sexual or urinary function should be checked. While also unpacking the controversy around PSA screening, overdiagnosis, active surveillance, robotic prostatectomy, focal therapy, radiotherapy, and the future of AI in prostate cancer diagnosis.

This is a practical, evidence-led conversation about men’s health, prostate cancer, testicular cancer, screening, stigma, and the questions men should feel able to ask their doctor.

💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.

💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com

📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook

📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation

🤖 Discover my digital twin here: http://DrKaran.ai

🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlist

About Dr Karan:

Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.

📱Connect with me:

Instagram: / drkaranrajan

Facebook: / drkaranr

TikTok: / dr.karanr

X: / drkaranrajan

Website: www.drkaranrajan.com

00:00 Prostate cancer symptoms men should know

01:02 Meet Professor Prabhakar Rajan

02:00 Why prostate cancer can have no symptoms

05:28 Are we overtreating early prostate cancer?

06:31 Surgery, radiotherapy and active surveillance

07:51 How MRI changed prostate cancer diagnosis

08:30 Why men avoid prostate health conversations

10:24 Prostate cancer risk in Black men

13:00 PSA tests: useful, imperfect and controversial

21:56 Why treatment decisions must be personal

24:39 Questions to ask before prostate surgery

25:10 Active surveillance and focal therapy

26:20 Nerve-sparing prostatectomy explained

28:22 Sexual function after prostate surgery

30:06 Testicular cancer symptoms in young men

31:18 What to do if you find a testicular lump

34:17 How to check your testicles properly

38:05 Could AI help diagnose prostate cancer?

40:25 The one thing men should do for their health

41:02 Why men’s health needs better conversations

#MensHealth #DrKaranRajan #MensHealthPodcast #Podcast

Gut health is about much more than what you eat. In this episode, Dr Karan Rajan speaks with Kaitlin Colucci about the gut-brain connection, IBS, bloating, stress, sleep, meal timing, yoga, and the nervous system.
They discuss why diet may only be one part of the gut health puzzle, how stress can affect digestion, why eating on the go may worsen symptoms, and how simple habits like breathwork, better sleep, mindful eating, fibre, and movement can support a healthier gut.
Kaitlin explains how the gut and brain communicate through the nervous system, why IBS is often misunderstood, and why gut symptoms are not always “just a food problem”.
This conversation also explores ultra-processed foods, caffeine, alcohol, artificial sweeteners, protein bars, fizzy drinks, meal timing, the migrating motor complex, yoga for IBS, and the role of social connection in digestion.
In this episode:
-Why gut health is not just about diet

- How stress affects digestion and gut motility

- What the gut-brain axis actually means

- Why IBS can involve nervous system sensitivity

- How sleep and circadian rhythm affect the gut

- Why grazing all day may worsen bloating

- How yoga, meditation, and breathwork may support IBS symptoms

- Practical ways to eat more mindfully

- The role of fibre, meal timing, and food diversity

💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.

💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com

📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook

📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation

🤖 Discover my digital twin here: http://DrKaran.ai

🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlist
About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
Connect with me:
Instagram: / drkaranrajan
Facebook: / drkaranr
TikTok: / dr.karanr
X: / drkaranrajan
Website: www.drkaranrajan.com
 00:00 Welcome Kaitlin Colucci
 01:34 Gut Health Rapid-Fire
 07:42 Why Eating on the Go Affects Digestion
 08:23 What People Miss About Gut Health
 09:04 The Gut-Brain Connection Explained
 11:16 How Stress Impacts Digestion
 12:21 IBS, Gut Sensitivity & Visceral Hypersensitivity
 15:26 How to Regulate Your Nervous System
 16:29 Mindful Eating, Food Diaries & Eating Without Distractions
 19:04 Reconnecting With Food & Social Eating
 22:13 Sleep, Circadian Rhythm & Gut Health
 23:37 Meal Timing, Grazing & the Gut “Clean-Up Crew”
 28:25 Yoga, IBS & Final Gut Health Advice
 36:46 Modern Gut Health & Final Takeaways
#GutHealth #IBS #GutBrainAxis #DrKaranRajan #KaitlinColucci

Male fertility is declining, but sperm count is only part of the story.
Dr Karan Rajan chats with Professor Sheryl Homa about male infertility, sperm DNA damage, lifestyle, heat exposure, environmental toxins, microbiome health, and why men’s fertility is often overlooked.
Professor Homa explains why infertility should be treated as a health issue for both partners, what semen analysis can and cannot tell you, and why sperm health may reflect wider problems such as diabetes, inflammation, kidney disease, hemochromatosis, stress and metabolic health.
In this conversation, we cover:
• Why global sperm counts appear to be falling

00:00 Sperm Counts Are Falling Globally

Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.

Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

Discover Throne's incredible new smart toilet device at http://thronescience.com

For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook

Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation

Discover my digital twin here: http://DrKaran.ai

Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlist
 
About Dr Karan:

Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
Connect with me:
Instagram: / drkaranrajan
Facebook: / drkaranr
TikTok: / dr.karanr
X: / drkaranrajan
Website: www.drkaranrajan.com
#MaleFertility #SpermHealth #MensHealth #DrKaran #podcast

Your gut microbiome affects far more than digestion. In this episode, Dr Karan Rajan sits down with gut health expert Jordan Haworth to break down the science of gut health, probiotics, fibre, acid reflux, oral microbiome health, fermented foods, GLP-1, bloating, sleep, fasting, and the everyday habits that actually improve your microbiome.

Here is a link to preorder Jordan's new book out June 18th: How to Gut Health: Science-backed hacks for immunity, metabolism and better sleep
https://lnk.to/howtoguthealth

We speak about:

• The connection between oral health and gut health
• Why chewing food properly changes digestion
• The truth about probiotics and fermented foods
• Best foods for beneficial gut bacteria
• Gut-friendly habits that improve digestion naturally
• Acid reflux hacks backed by science
• Whether greens powders and fibre gummies are worth it
• The role of fasting, sleep, exercise and stress on the microbiome
• Why gut health affects metabolism, immunity, mood and more

 00:00 Gut Health Starts In The Mouth
 01:15 Why Chewing Improves Digestion
 04:10 Eating Slowly, GLP-1 & Feeling Full
 06:55 Oral Microbiome, Mouthwash & Gum Disease
 11:25 Acid Reflux & The Lower Oesophageal Sphincter
 19:40 Bitter Foods, Coffee & Digestion
 22:05 Nausea, Ginger & Fart Walking
 31:00 Foods That Feed Bifidobacteria
 34:00 Fermented Foods & Lactic Acid Bacteria
 37:50 Slow-Fermenting Fibres For The Colon
 40:35 Prebiotics, Probiotics & Postbiotics Explained
 50:40 Nature, Sleep, Exercise & The Microbiome
 53:10 Fasting, Akkermansia & Gut Rest
 54:45 Sweeteners, Vinegar, Greens Powders & Fibre Gummies

Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.

Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

Discover Throne's incredible new smart toilet device at http://thronescience.com

For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook

Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation

Discover my digital twin here: http://DrKaran.ai

Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlist
About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor.
Connect with me:
Instagram: / drkaranrajan
Facebook: / drkaran
TikTok: / dr.karanr
X: / drkaranrajan
Website: www.drkaranrajan.com
#GutHealth #Microbiome #DigestiveHealth #Probiotics #DrKaran

Your phone is not just distracting you, it may be changing what your brain finds rewarding.

In this episode of Dr Karan Explores, Dr Karan Rajan speaks with neuroscientist TJ Power, founder of DOSE Lab, about dopamine, phone addiction, AI, “brain rot,” digital anhedonia, and why modern technology can make ordinary life feel less pleasurable. TJ’s DOSE framework focuses on dopamine, oxytocin, serotonin, and endorphins, the four brain chemicals he says are being disrupted by the way modern humans live. 

This conversation explores why so many of us feel stuck in loops of scrolling, distraction, apathy, and low motivation, and what it takes to reset our relationship with stimulation without pretending technology is “bad.” TJ shares why he believes 72 hours without screens can feel transformative, why boredom is harder than it sounds, and why becoming a “professional unplugger” may be one of the most important skills for the next generation. 

In this episode, we cover:

• What dopamine actually does beyond the online “dopamine detox” clichés
• Why phones, short-form content, sugar, alcohol, and AI can hijack reward pathways
• “Digital anhedonia”: Why normal life can start to feel dull or boring
• The 72-hour unplugged experiment and what happens by day two and day three
• Why boredom, stillness, walking, and doing nothing can restore creativity
• The default mode network and why your best ideas may need silence
• AI, “brain rot,” passive screen time, and outsourcing your thinking
• How to become a “professional unplugger” without quitting modern life

🎬 Chapters

01:13 – Why Modern Life Is Rewiring Our Brains
03:18 – What Dopamine Actually Does
06:06 – Phones, Short-Form Content & Dopamine Overload
09:28 – Why Nothing Feels Fun Anymore
12:27 – How to Break the Stimulation Loop
14:01 – 72 Hours Without Screens: What Happens to Your Brain
17:49 – Boredom, Creativity & the Default Mode Network
21:41 – Instant Gratification and the Collapse of Waiting
22:47 – AI, Brain Rot & Outsourcing Your Thinking
29:34 – Passive Screen Time vs Active Technology Use
32:37 – Are Some Brains More Dopamine-Hungry?
39:04 – Stillness, Silence & Rebuilding Attention
42:35 – AI Relationships, Oxytocin & Artificial Connection
46:10 – Why Technology Evolves Faster Than the Human Brain
48:27 – Dopamine and Why Time Feels Faster
52:03 – Becoming a Professional Unplugger
53:31 – Final Takeaway: Quiet Mornings, Coffee & No Phone

💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation🤖 Discover my digital twin here: http://DrKaran.ai🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlistAbout Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.📱Connect with me:Instagram: / drkaranrajanFacebook: / drkaranrTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com

#Dopamine #BrainRot #PhoneAddiction #Neuroscience #DigitalDetox

💬 Protecting first time parents from the realities of childbirth comes at a price. Not knowing how difficult it can be often leaves them unprepared - feeling guilty if it doesn’t go “perfectly”.

⚡With all the misinformation around - and shockingly high maternal mortality rates in the US - Dr Jennifer Lincoln has decided to take childbirth into her own hands. The social media educator has just released The Birth Book: An OB-GYN’s Guide to Demystifying Labor and Delivery.

🎧 Stay tuned to find out:

➡ What a “normal” labour really looks like

➡︎ What you can say “no” to during labour (Hint: anything)

➡︎ The truth about epidurals, C-sections and natural birth

➡︎ That children can be healthy no matter how childbirth goes

➡︎ Why the US is the highest rich nation for maternal mortality

➡︎ How 1 in 3 births cause psychological trauma for the mum

#DrKaran, #Pregnancy, #BirthScience, #Labour, #BirthTrauma, #ChildbirthMyths #WomensHealth, #MedicalScience, #HealthEducation, #MythBusting

Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 

📕 Chapters

(0:00) Introduction - We need to be realistic about childbirth

(2:10) How should women really prepare for birth?

(3:27) Are doctors good patients when it comes to childbirth?

(5:16) What does a normal first time labour really look like?

(7:11) How to know when it’s time to go to the hospital

(8:28) Should you pack a hospital bag?

(10:07) What it really means to induce labour

(14:09) Is there a best birthing position?

(16:37) What can you say “no” to?

(18:54) How to tell the difference between optional and necessary interventions

(20:23) How different is second time labour?

(22:38) What to do when a baby’s breach

(24:22) Why you shouldn’t feel guilty about an epidural

(28:51) Does vaginal seeding help?

(29:25) Conversations to have before labour starts

(31:56) The problem of “maternity deserts” in the US

(34:52) Why maternal mortality is so high in the US

(35:57) Why do black women have the worst childbirth outcomes?

(39:16) What to consider if you’re having a homebirth

(40:09) Why traumatic births are much more common than we realise

🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 

🤖 Discover my digital twin here: http://DrKaran.ai 

🔥  Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.

🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 

📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5

🎙️ An OG Podcasts production.

About Dr Karan:

Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.

📱Connect with me:

Instagram: https://www.instagram.com/drkaranrajan/   

Facebook: https://www.facebook.com/DrKaranR/  

TikTok: https://www.tiktok.com/@dr.karanr  

X: https://twitter.com/drkaranrajan  

Website: https://linktr.ee/ThisisVitalInformation

GLP-1 weight loss drugs are changing medicine, but are we talking about them in the right way? In this episode, Dr Karan Rajan speaks with Dr Federica Amati about GLP-1s, food noise, metabolic health, appetite, gut health, muscle loss, side effects and why nutrition support matters.

Dr Federica Amati explains why these medications should not be seen as simple “weight loss drugs”, how food noise differs from real hunger, and what people should know before, during and after GLP-1 treatment.

📗 Pre-order Dr Federica's book 'The Appetite Reset' here: https://shor.by/fP5H

In this conversation, we cover:

* Why diet remains one of the biggest drivers of chronic disease

* What GLP-1s actually do beyond weight loss

* The difference between homeostatic hunger, hedonic hunger and microbiome-driven hunger

* Why food noise can dominate appetite and eating behaviour

* How protein and resistance training can help protect muscle

* Why micronutrients, fibre and hydration matter on GLP-1s

* The risks of black market or poorly regulated weight loss injections

* How gut health may influence appetite, side effects and long-term success

* Why whole foods and nutrient density still matter most

Chapters

00:00 Preview: GLP-1s, food noise and diet

01:18 Welcome and Dr Federica Amati introduction

02:18 Why GLP-1s need lifestyle and nutrition support

03:21 Diet, chronic disease and preventable deaths

05:08 Who should be using GLP-1 medications?

07:18 Why GLP-1s are metabolic health medications

08:13 GLP-1s, the brain and food noise

08:51 Homeostatic, hedonic and microbiome-driven hunger

09:22 Internal vs external food noise

11:37 Practical ways to reduce food noise

13:40 Loam sponsor read

14:39 Why digestion starts in the brain

17:29 Fullness, stomach stretch and meal replacements

19:47 GLP-1s, muscle loss, protein and resistance training

21:02 Micronutrients, hydration and nutrient density

24:06 Supplements and Mediterranean dietary patterns

26:10 Body image, identity and emotional changes on GLP-1s

28:34 Regulation, TikTok access and black market risks

30:47 Gut microbiome, appetite and natural GLP-1 signalling

42:31 Preparing your gut, managing side effects and final advice

💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.

💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com

📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook

📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation

🤖 Discover my digital twin here: http://DrKaran.ai

🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlist

About Dr Karan:

Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.

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Instagram: / drkaranrajan

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Website: www.drkaranrajan.com

#GLP1 #WeightLossDrugs #FoodNoise #GutHealth #MetabolicHealth

💬 How can you tell if a supplement actually does what it promises to do? There are so many on the market that are underdosed, understudied and not backed up by science. So before you choose your next supplement - this is the data that should inform your decision.

⚡When Dr Karan created LOAM, his aim was to create a fibre supplement backed up by clinically robust data. In this special episode, he outlines the lengthy process that went into making sure it actually delivers results.

🎧 Stay tuned to find out:

➡ What a preclinical study is - and why they are essential

➡︎ How a study can actually show you what’s going on inside someone’s gut

➡︎ Why propionate is so important for gut health - and how LOAM boosts it

➡︎ Why LOAM produces less gas and bloating than other fibre supplements

➡︎ What trials are coming in the future for LOAM  

#DrKaran, #LOAM, #Supplements, #Microbiome, #Butyrate, #GutHealth, #MedicalScience, #HealthEducation, #MythBusting

Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 

📕 Chapters

(0:00) Introduction - How to choose a supplement that works

(0:41) Why preclinical studies are so important

(4:27) The combination that creates gold standard results

(8:14) How the LOAM preclinical study actually worked

(11:44) Surprising results from the LOAM trials

(14:02) The importance of the short-chain fatty acid propionate

(17:43) Why LOAM produces results so quickly 

(20:02) Why supplements don’t impact all people the same

(22:18) How LOAM produces less gas than other fibre supplements

(25:36) Fibre fermentation💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=spotify&utm_medium=podcast&utm_campaign=podcast_loam_clinical_trials

🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 

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📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share

🎙️ An OG Podcasts production.

About Dr Karan:

Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.

📱Connect with me:

Instagram: https://www.instagram.com/drkaranrajan/   

Facebook: https://www.facebook.com/DrKaranR/  

TikTok: https://www.tiktok.com/@dr.karanr  

X: https://twitter.com/drkaranrajan  

Website: https://linktr.ee/ThisisVitalInformation