Can psilocybin treat depression within a day? In this episode, Dr Karan Rajan sits down with psychedelic researcher Dr Rayyan Zafar to break down the science of psilocybin, treatment-resistant depression, brain scans, microdosing, and whether psychedelic therapy could become a real part of mainstream mental health care.
They explore why current antidepressants do not work for everyone, how psychedelics may affect the brain differently, what researchers are seeing on scans after a single dose, and why the conversation around psychedelic therapy is far more nuanced than internet hype suggests.
In this episode:

• Why psychiatry needs new tools for depression
• Why SSRIs do not work for everyone
• How psilocybin interacts with serotonin receptors
• The idea of a “plastic window” after psychedelic therapy
• Whether psychedelics could help healthy people, not just patients
• What the evidence says about microdosing
• The real safety questions around psychedelic treatment
• DMT, short-acting psychedelics, and where the field may go next

00:00 - Welcome Dr Rayyan Zafar
04:35 - How psychedelics work in the brain
07:29 - Psychedelics, culture and meaning-making
08:21 - What counts as treatment-resistant depression?
15:26 - Could psychedelics become preventative medicine?
17:20 - Depression, rumination and the default mode network
20:37 - The “plastic window” and why therapy matters
26:09 - The truth about Microdosing
33:20 - Safety, screening and who should avoid psychedelics
42:04 - DMT, ayahuasca and future treatments
44:04 - Why short-acting psychedelics matter
About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor.

 🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com

🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook

📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5

🔥 Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.

🤖 Discover my digital twin here: http://DrKaran.ai

Connect with me:
Instagram: / drkaranrajan
Facebook: / drkaran
TikTok: / dr.karanr
X: / drkaranrajan
Website: www.drkaranrajan.com
#Psilocybin #MentalHealth #Neuroscience #PsychedelicTherapy #healthpodcast

💬 Health isn’t just about what you eat - it’s about when. Meal timing matters much more than you might realise. The same food eaten at different times can have wildly different effects on your body. 

⚡To discuss the emerging field of chrononutrition, Dr Karan is joined by Adriano dos Santos - known as The Circadian Nutritionist. Together they explain how your organs and even your gut microbiome keep time - operating on a circadian clock!

🎧 Stay tuned to find out:

➡ How clock genes throughout our entire body impact our health

➡︎ Why poor meal timing can create a lack of energy, sleep struggles and even IBS

➡︎ How late nate phone scrolling isn’t as bad as you think

➡︎ Why late night snacking and evening exercise confuses your body clock

➡︎ Why not all fasting is created equal

➡︎ Which foods and habits will improve your health and body clock the fastest

#DrKaran, #MedicalScience, #HealthEducation, #HealthTips, #MedicalScience, #MealTiming, #ChronoNutrition, #CircadianNutrition, #DietTips, #GutHealth,

Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 

📕 Chapters

(0:00) Introduction - Why chrono nutrition is so important for health

(02:15) The health impacts of not paying attention to meal timing

(04:46) How  butyrate interacts with your internal clock

(06:56) What happens when your gut timing is out of sync

(10:35) The gut clock’s role in sleep

(14:37) How late night phone scrolling impacts your body clock

(18:40) Should you avoid late night snacking?

(21:58) How the same calories affect you differently depending on when you eat them

(26:26) Should you eating your fibre earlier in the day?

(31:19) Why fasting might not be as healthy as we thought

(36:09) How body clock disruption could cause IBS

(40:12) Specific food and habits to improve

🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 

🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 

📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share

🔥  Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.🤖 Discover my digital twin here: http://DrKaran.ai

🎙️ An OG Podcasts production.

About Dr Karan:

Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.

📱Connect with me:

Instagram: https://www.instagram.com/drkaranrajan/   

Facebook: https://www.facebook.com/DrKaranR/  

TikTok: https://www.tiktok.com/@dr.karanr  

X: https://twitter.com/drkaranrajan  

Website: https://linktr.ee/ThisisVitalInformation

The best sleep schedule (according to science) isn’t just “8 hours”, it’s timing + consistency.

In this episode, Dr Karan Rajan speaks with Professor Gina R. Poe about how to build a sleep schedule that supports deep sleep, REM sleep, memory, and long-term performance, using the levers that actually move the needle: consistent timing, light exposure, temperature, naps, and meal timing. 

In this conversation, we cover:

• Why sleep consistency is repeatedly linked with performance and healthier ageing outcomes 

• A practical “best schedule” window (and why earlier sleep helps catch key deep-sleep biology) 

• How light at night disrupts circadian timing (and why dim red light matters) 

• Naps: when they help, and when they can backfire on night sleep 

• Temperature and why overheating can reduce REM sleep 

• Meal timing (“chrononutrition”) and why late meals can fragment sleep 

• Plus: REM sleep, sleep spindles, memory, alcohol, and why some sedatives alter sleep architecture 

🎬 Chapters
01:03 – Introducing Professor Gina R. Poe
01:51 – REM sleep: remembering AND forgetting
02:15 – Crick’s REM-for-forgetting hypothesis
04:16 – Hippocampus → neocortex: how memories move during sleep
06:06 – Stress “sweet spot” for learning (too little vs too much) 
07:39 – Rats in space: learning in 3D/zero gravity
11:26 – Locus coeruleus (“blue spot”): arousal, learning, and REM switching
14:26 – Nightmares/PTSD: why REM needs the LC to go quiet
17:33 – Alcohol + sedatives: how they can reduce spindles and REM 
18:47 – Sleep architecture 101: cycles, deep sleep, REM, spindles 
20:48 – Growth hormone timing + why circadian alignment matters 
21:27 – “You can’t catch up”: why your body has a schedule 
23:17 – Transition into REM: spindles, K-complexes, P-waves 
25:53 – How to increase spindles: learning something new 
27:32 – What reduces spindles: sleeping pills/benzos/alcohol 
28:29 – Wearables vs EEG: what tracking can and can’t tell you 
31:27 – Wearables + alcohol effects + women & temperature tracking 
33:19 – Hormones & sleep: what we know, what’s inconclusive (and why) 
36:59 – New parents: shifts, feeding timing, and protecting circadian rhythm 
40:15 – Night feeds: don’t turn on bright lights (use dim red light) 
41:29 – The best sleep schedule (science-based): consistency + timing 
43:38 – Naps: when they help and when they hurt bedtime 
44:42 – Temperature: why overheating can reduce REM sleep 
47:28 – Meal timing: avoid late meals + use meals to reset jet lag 
49:16 – The research gap: women’s cycles, diaries, and better studies 

🚽 Discover Throne’s incredible new smart toilet device at ⁠http://thronescience.com⁠🔥 Try LOAM and get an additional 10% with code POD10: https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores🔥 Get my free weekly newsletter filled with easy-to-action health tips and science: ⁠https://drkaran.beehiiv.com/subscribe⁠🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: ⁠https://geni.us/DrKaranBook⁠📕 Pre-order my new book, This Is Vital Information: ⁠https://linktr.ee/ThisisVitalInformation

About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor.

📱Connect with me:
Instagram: / drkaranrajan
Facebook: / drkaran
TikTok: / dr.karanr
X: / drkaranrajan
Website: www.drkaranrajan.com

#SleepScience #CircadianRhythm #SleepSchedule #REMSleep #DeepSleep

💬 GLP-1 pizzas and ready meals are now on the menu. Telehealth pharmacies are selling dodgy versions of the drugs to the masses. And new, more powerful drugs are about to arrive.

⚡The weight loss economy is booming - and it’s reshaping society. GLP-1 and weight loss expert Dr. Spencer Nadolsky is back on the podcast to fill us in on the latest. From myth busting and unearthing telehealth scams - to showing the genuinely amazing things these drugs are capable of.

🎧 Stay tuned to find out:

➡ Whether you should spend money on GLP-1 pizzas and ready meals

➡︎ Why telehealth companies and their compounded drugs are so dangerous

➡︎ Whether GLP-1 “drops” and supplements actually work

➡︎ Why alcohol isn’t a big problem for people on GLP-1s

➡︎ Whether GLP-1s really increase fat cells in the body

➡︎ How GLP-1s can help with PCOS and other diseases

#DrKaran, #MedicalScience, #HealthEducation, #HealthTips, #MedicalScience, #GLP1, #Ozempic, #Wegovy, #Semaglutide, #Retatrutide, #WeightLossDrugs

Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 

📕 Chapters

(0:00) Introduction - Are GLP-1 “friendly” foods any good?

(4:18) Can diet fix nausea issues of GLP-1s?

(6:17) Why people are spending less on restaurants and take-out

(9:15) How GLP-1s interact with alcohol consumption

(14:33) Is there a pancreatitis risk from GLP-1s?

(16:07) Do these drugs increase the number of fat cells in the body?

(20:21) The problem with telehealth companies

(23:00) Why compounded weight loss drugs are cause for concern

(33:02) Do GLP-1 drops work?

(36:46) The truth behind “GLP-1 boosting” supplements

(44:17) Is Retatrutide the future of weight loss? 

(50:34) How GLP-1s help autoimmune and inflammatory diseases

(54:26) GLP-1 gene therapy

🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 

🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 

📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share

🔥  Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.

🎙️ An OG Podcasts production.

About Dr Karan:

Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.

📱Connect with me:

Instagram: https://www.instagram.com/drkaranrajan/   

Facebook: https://www.facebook.com/DrKaranR/  

TikTok: https://www.tiktok.com/@dr.karanr  

X: https://twitter.com/drkaranrajan  

Website: https://linktr.ee/ThisisVitalInformation

Family meals aren’t just a “nice-to-have”. They’re a longevity habit hiding in plain sight.In this episode, Dr Karan Rajan and Shawn Stevenson unpack why eating together can improve kids’ nutrition, reduce ultra-processed food reliance, support healthier eating behaviours, and strengthen the social bonds that consistently show up in long-term health and longevity conversations.You’ll hear about:Why routines (sleep + meals) matter more than perfectionHow tech and modern “kitchen culture” has changed how we eatThe evidence linking shared meals to kids’ nutrition and health outcomesThe “minimum effective dose” of family meals (and what studies associate with it)How to guide kids around food without fear-mongering or rigid restrictionUltra-processed food trends in children and how to build a healthier micro-culture at home🎬 Chapters:01:07 – Why this “hidden longevity habit” matters04:25 – Childhood responsibilities & early parenting perspective05:01 – “Kids want to sleep”: Meeting needs, not chasing perfection06:16 – Why brains love routines (sleep culture & rituals)08:09 – Nap time reality & the dog vs kid routine comparison09:04 – Kids growing up in a different world10:06 – Meal structure & defining “kitchen culture”13:22 – The life-skill decline: Kids relying on microwaves14:06 – What research shows: Shared meals, nutrients & less UPF16:54 – Eating as a cultural moment 17:47 – The “minimum effective dose”18:18 – Family dinner as stress relief19:40 – Shared meals, supervision & why “beige food” wins21:05 – Shared meals as a non-diet longevity lever21:54 – “Our genes expect us to eat together” 25:18 – Blue Zones: the overlooked role of communal meals29:00 – Protecting kids from nutrition fear-mongering30:23 – Dogma phases: Diets, trends, and staying grounded31:05 – Ultra-processed food in kids: 1999 → 2018 (the data)32:48 – Building a “micro-culture” at home 34:11 – “Both-and” parenting: Sovereignty, flexibility, and belonging36:12 – “Kids don’t listen, they watch”: Modelling habits that stick36:47 – Food, culture & fitting in 42:59 – The 80/20 mindset & starting small with cooking44:11 – UPFs, oils & nutrition nuance (olive oil vs canola sidebar)46:18 – Nutrition trend cycles: low fat → keto → high protein47:30 – Creating a “vibe” in the kitchen49:28 – Invite kids into the kitchen🚽 Discover Throne’s incredible new smart toilet device at ⁠http://thronescience.com⁠🔥 Try LOAM and get an additional 10% with code POD10: https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores🔥 Get my free weekly newsletter filled with easy-to-action health tips and science: ⁠https://drkaran.beehiiv.com/subscribe⁠🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: ⁠https://geni.us/DrKaranBook⁠📕 Pre-order my new book, This Is Vital Information: ⁠https://linktr.ee/ThisisVitalInformatioAbout Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor.📱Connect with me:Instagram: / drkaranrajanFacebook: / drkaranTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com#Longevity #FamilyMeals #NutritionScience #Parenting #UltraProcessedFoods

💬 Are your supplements helping you… or are you just paying for sawdust?

The supplement industry is booming, but it’s also one of the easiest industries to fake. In this episode, Dr Karan is joined by Dr Darshan Shah (surgeon and longevity expert) to break down what actually works, what’s likely a waste of money, and how to avoid supplements that can genuinely cause harm.

⚡We cover contamination, Amazon “ratings”, the creatine gummy scandal, drug interactions, GLP-1 supplement marketing, and the simple blood tests that help you figure out what YOU actually need.

🎧 Stay tuned to find out:

➡ Why so many supplements don’t contain what the label says

➡ The “essentials” most people are missing (and how to test for them)

➡ Why gummies are often just expensive sweets

➡ The supplement mistake that can mess with blood tests, surgery and medications

➡ How to spot quality: third-party testing, COAs and real dosing

➡ Why GLP-1 “supplements” are mostly marketing

➡ The simplest framework to stop wasting money

#DrKaran #HealthPodcast #MedicalScience #HealthEducation #Supplements #Creatine #Longevity #GutHealth

Don't miss an episode! Subscribe NOW!

📕 Chapters

(0:00) Coming up (episode teaser)

(0:56) Intro: Dr Darshan Shah returns (supplements, quality, and what actually works)

(1:51) The real problem: “unregulated” quality + fake Amazon ratings

(3:36) Dr Shah’s supplement stack (and why powders make compliance easier)

(4:50) Creatine: why he takes it (and how much)

(8:43) Creatine + poor sleep: the cognition link

(11:24) The patient story: supplements causing blood sugar spikes

(14:33) Supplements are chemicals: liver injury + drug interactions

(15:45) Dr Karan’s creatine kidney scare (creatinine vs real kidney function)

(18:57) Sponsor: LOAM

(20:06) The creatine gummy scandal: “I was basically eating Haribo”

(22:18) A simple consumer playbook: the “bell curve” of supplement users

(24:06) The essentials list (what most people actually need)

(27:02) The 3 buckets: dose, form, and evidence (why gummies usually fail)

(29:58) Should you use PubMed (and how not to get misled by studies)

(34:48) Why almost no supplement companies run real trials

(36:42) “Black labelling”: influencer supplements as a cash grab

(38:43) Surgery story: the St John’s Wort mistake that wouldn’t stop bleeding

(43:22) How to check quality: third-party testing, heavy metals, and COAs

(48:07) Sponsor: Throne

(49:05) GLP-1 “supplements”: marketing 101 vs real value

(51:46) Where to start: the key blood tests to guide supplements

(53:20) Does supplement timing matter (or is consistency the real win)?

(54:28) Omega-3 quality: fish oil vs algae vs krill

(56:48) Red flags: proprietary blends + choosing the right magnesium forms

(57:59) Next-gen probiotics vs the simplest lever: fibre

(1:03:12) Dr Shah’s “simple stack” recap

(1:03:45) Closing

🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com
🔥 Try LOAM and get an additional 10% with code POD10: https://loamscience.com/
🔥 Get my free weekly newsletter filled with easy-to-action health tips and science: https://drkaran.beehiiv.com/subscribe
🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook
📕 Pre-order my new book, This Is Vital Information: https://linktr.ee/ThisisVitalInformation

We track our steps, sleep, calories… even glucose. So why are we STILL getting sicker?

In this episode, Dr Karan sits down with Josh Clemente (former SpaceX engineer and founder of Levels) to explore a big question: Are health wearables actually helping us, or are we just collecting data with no real direction?

Josh explains why aerospace treats “health” totally differently to medicine, why we should measure when we’re healthy (not just when things go wrong), and what “biological observability” could mean for the future of healthcare.

🎧 Stay tuned to find out:

➡ Why “if you’re healthy, there’s no reason to measure” is backwards

➡ What SpaceX taught Josh about monitoring systems vs monitoring humans

➡ Why data is neutral (and why interpretation is everything)

➡ The biggest risks of wearables: anxiety, obsession, disordered habits

➡ Why CGMs can be powerful, but easy to misuse without context

➡ What a real “health operating system” might look like in 3–10 years

➡ The uncomfortable truth about health inequality and the future of tech

#DrKaran #HealthPodcast #MedicalScience #HealthEducation #Wearables #CGM #MetabolicHealth #Longevity #Levels

Don't miss an episode! Subscribe NOW: / @drkaran

📕 Chapters

(0:00) Coming up (episode teaser)

(0:57) Intro: the biggest self-experiment in history

(1:48) We have more health data than ever… so why are we unhealthier?

(4:14) Dr Karan’s CGM “flip-flop” (healthy users tracking glucose)

(6:38) Engineer vs doctor: two ways of solving the same problem

(6:45) SpaceX/NASA life-support mindset: monitor everything

(7:36) “Hundreds of data channels” for spacecraft… zero for humans

(8:50) “Measure when healthy” (scarcity mindset vs abundance mindset)

(9:44) The airplane analogy: monitoring should reduce anxiety

(10:24) What medicine can learn from aviation safety

(12:47) Survivorship bias and why healthcare optimises the wrong thing

(14:14) Why we only measure once disease shows up (and why that’s insane)

(15:24) “I’m lean but my glucose runs hot” (why averages can mislead)

(16:46) Personalised care needs data (but not obsession)

(23:35) Health proxies, blue zones, and why we get cause and effect wrong

(24:45) The dark side of wearables: sleep anxiety, CGM “gamifying” health

(26:16) Goodhart’s Law: when a target becomes the measure

(28:11) CGM isn’t the goal, it’s a tool (context matters)

(30:26) The future: multi-marker wearables and a “digital twin”

(35:14) How close are we to continuous monitoring (3–10 years)?

(37:04) AI as the interface to complexity (and what it enables)

(39:40) The missing lever in most health advice: your zip code

(41:15) Will this tech widen inequality, or become accessible?

(44:44) CGMs vs misleading food marketing (and how systems might change)

(46:11) Is living longer worth it if you obsess over data?

(47:44) Fatherhood, healthspan, and avoiding the avoidable

(48:32) Josh’s bloodwork story: seeing trend lines and making small tweaks

(50:03) “Health isn’t easy, but it is simple”

(51:15) Closing

🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com

🔥 Try LOAM and get an additional 10% with code POD10: https://loamscience.com/

🔥 Get my free weekly newsletter filled with easy-to-action health tips and science: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook

📕 Pre-order my new book, This Is Vital Information: https://linktr.ee/ThisisVitalInformation

About Dr Karan:

Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he tackles topics from nutrition and metabolism to brain health and longevity, while dispelling myths with a touch of dark humour.

📱Connect with me:

Instagram: / drkaranrajan

Facebook: / drkaranr

TikTok: / dr.karanr

X: / drkaranrajan

Website: https://linktr.ee/ThisisVitalInformation

💬 What does it actually take to rebuild your life after addiction?

Ken Rideout has lived multiple lives: Former prison guard, Wall Street trader, opioid addict… and now the fastest marathoner in the world over 50.

⚡In this episode, Ken opens up about the darkest moment that forced him to change, what opioid withdrawal REALLY feels like, and the identity shift that helped him go from rock bottom to elite endurance athlete.

🎧 Stay tuned to find out:

➡ The “rock bottom” moment that finally flipped the switch

➡ What opioid withdrawal is actually like

➡ How Ken used discipline, discomfort and running to rebuild his identity

➡ The truth about hiding addiction inside a “normal” life

➡ Why ambition can quietly steal your presence (especially as a parent)

➡ The uncomfortable reality of CPR, end-of-life decisions and quality of life

#DrKaran #HealthPodcast #MedicalScience #HealthEducation #AddictionRecovery #MentalHealth #Fitness #Running #Longevity

Don't miss an episode! Subscribe NOW: https://www.youtube.com/channel/UCREKb1GS1jwZIpH4qn9tyuA

📕 Chapters

(0:00) Coming up (episode trailer)

(1:22) Introduction (in-person pod with Ken Rideout)

(3:37) Growing up around addiction, violence and instability

(4:07) “My mind always needed to be busy”

(5:56) Moving to New York and quitting drinking (finance culture)

(7:47) The injury that started it: ankle surgery + Percocet

(8:01) Wall Street insecurity and imposter syndrome

(10:00) Marriage, adoption and battling addiction in secret

(10:34) The withdrawal trap: Subutex vs Percocet

(11:00) The shame loop: “What are you doing?”

(11:12) Detox in secret and hiding it from his wife

(14:37) Running through withdrawal (10 miles a day)

(14:56) The balcony moment

(14:59) “I’d rather be dead than live like this”

(15:05) The final straw: telling his wife the truth

(15:27) Vivitrol and the first real relief

(23:43) Covid, routines collapsing and old habits creeping back

(32:07) Parenting, ambition and being present

(40:32) Facing death as a doctor (why planning matters)

(45:59) CPR myths: what TV gets wrong

(49:15) Sponsor: Throne

(50:16) Ambition vs presence (what matters long-term)

(1:01:31) Purpose outside work and parenting

(1:03:08) “Get out past the break” (closing)

🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com

🔥 Try LOAM and get an additional 10% with code POD10: https://loamscience.com/

🔥 Get my free weekly newsletter filled with easy-to-action health tips and science: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook

📕 Pre-order my new book, This Is Vital Information: https://linktr.ee/ThisisVitalInformation

About Dr Karan:

Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor.

📱Connect with me:

Instagram: / drkaranrajan

Facebook: / drkaranr

TikTok: / dr.karanr

X: / drkaranrajan

Website: https://linktr.ee/ThisisVitalInformation

💬  When it comes to improving your health, what comes to mind first? Working on your muscles? Improving your gut? What about strengthening your BONES?

⚡Bone health is massively overlooked by most people - and yet it has such a huge impact on how you feel, how much pain you experience and whether you’ll age gracefully or not.

⚡That’s why I’ve brought on Belinda Beck, founder of the Bone Clinic - who’ll help us understand the importance of bone health, and what you can do to improve yours today. 

🎧 Stay tuned to find out:

➡ The biggest signs of poor bone health - and how to strengthen them

➡︎ How bone is an alive and  highly metabolic tissue

➡︎ Why fears about weight-lifting in children are overblown

➡︎ What  Wolff’s Law teaches us about maintaining healthy bones lifelong

➡︎ Why some exercises are simply not enough for bone health

➡︎ Why bone health is so closely linked to risk of death

#DrKaran, #MedicalScience, #HealthEducation, #HealthTips, #MedicalScience, #BoneStrength, #BoneHealth, #Fitness,

Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 

📕 Chapters

(0:00) Introduction

(0:42) Why you should care about your bone health

(1:45) Signs your bone health isn’t optimal

(2:40) How to strengthen your bones

(4:08) The biology of bones and how they change through life

(7:36) Why children CAN lift weights for bone health

(9:03) Should babies be doing acrobatics?

(12:23) Can weights help you gain bone density?

(15:01) Bone health in perimenopause and menopause

(17:20) Is walking enough for healthy bones?

(19:05) Can too much exercise cause bone issues?

(23:35) Should you screen for bone health?

(28:40) Why bone health is linked to risk of death

(31:48) Is it ever too late to fix your bones?

(34:08) How active is our bone as a tissue?

(36:34) Fizzy drinks and bones: Fact or fiction?

(38:51) The role of collagen supplements

🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 

🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 

📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share

🔥  Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.

🎙️ An OG Podcasts production.

About Dr Karan:

Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.

📱Connect with me:

Instagram: https://www.instagram.com/drkaranrajan/   

Facebook: https://www.facebook.com/DrKaranR/  

TikTok: https://www.tiktok.com/@dr.karanr  

X: https://twitter.com/drkaranrajan
Website: https://linktr.ee/ThisisVitalInformation

💬 The GLP-1 weight loss movement is blowing up. On the one hand, we now have a drug that tackles the obesity epidemic like never before. On the other, we’re seeing the rise of food anxiety and the return of thin-at-all-costs culture. Drugs like Ozempic and Wegovy are reshaping medicine, culture and the economy.

⚡So to get the latest on these rapid advancements, we speak to endocrinology and metabolism specialist Dr Rekha Kumar. She takes us through the growing list of benefits provided by GLP-1 drugs - and the dangers. As well as tackling the wider field of “gray market” peptide use.

⚡Today’s guest is Dr Rekha Kumar, an expert in metabolic and hormone health. Together we dig deep into GLP-1 use - the latest science on the benefits and the dangers.

🎧 Stay tuned to find out:

➡ Why GLP-1 reliance is leading some to ignore good health practices

➡︎ Are we seeing the return of 80s diet culture and the “Almond mom”?

➡︎ How GLP-1s impact overall health - including menopause care

➡︎  Why long-term use may be needed to tackle growing weight regain concerns

➡︎ How peptides like retatrutide are becoming more popular in longevity circles

➡︎ Why oral Wegovy is a total game-changer

#DrKaran, #MedicalScience, #HealthEducation, #HealthTips, #MedicalScience, #GLP1, #Ozempic, #Wegovy, #Semaglutide, #Retatrutide, #WeightLossDrugs

Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 

📕 Chapters

(0:00) Introduction

(0:54) How GLP-1s are affecting every area of life

(2:58) Are people giving up on standard diet and exercise advice?

(5:32) A return of 80s diet culture and “heroin chic”

(8:44) What GLP-1s teach us about willpower

(13:28) The wider societal impacts of weight loss drugs

(17:02) What you need to understand about “food noise”

(21:48) Beyond weight-loss, how GLP-1s impact menopause and more

(26:55) The cancer link

(31:32) What are the proven pregnancy risks?

(35:55) The “gray market” of peptides – are they safe?

(40:37) The rise of retatrutide in longevity circles

(43:55) Why oral Wegovy is a total game-changer

(47:09) Why biohackers and scientists need to come together

🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 

🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 

📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5

🔥  Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.

🎙️ An OG Podcasts production.

About Dr Karan:

Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.

📱Connect with me:

Instagram: https://www.instagram.com/drkaranrajan/   

Facebook: https://www.facebook.com/DrKaranR/  

TikTok: https://www.tiktok.com/@dr.karanr  

X: https://twitter.com/drkaranrajan  

Website: https://linktr.ee/ThisisVitalInformation