Episode 120 hosts Dr Jean Carruthers based in Vancouver, Canada.

In the late 1980's working as an opthalmologist, Dr Carruthers and her husband Dr Alistair Carruthers (a dermatologist) pioneered how botulinum toxin can be used specifically for cosmetic purposes - now the most common cosmetic procedure in the world.

Dr Carruthers is globally-recognised for her expertise in research and has authored more than 300 peer reviewed scientific publications, 70 book chapters and 9 textbooks. She's given thousands of presentations on cosmetic treatments and continues to lecture on the world stage as a keynote speaker.

We first discuss how she learnt to use botulinum toxin and the day she deliberately treated the first patient in the world for frown line treatment - her receptionist Cathy Swann. We learn how her peers initially dismissed the idea of injectable cosmetic treatments and yet over time, how Jean and Alistair designed the first trials and worked with Allergan to brand the treatment as 'Botox'.

We explore how the current protocols (known as prescribing information) were designed and learn how Dr Carruthers still does things to this day.

We also look into the future of toxins to discuss longer and shorter acting products, the issue of toxin resistance, which brands she favours and much, much more!

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