What do a 1940s scientific breakthrough, a 2000s public health scandal, and your perimenopause symptoms have in common? Answer: Estrogen.

In this episode, the Docs kick off a hormone therapy series by telling listeners the dramatic story of estrogen. How "she" got famous, suffered a scandal, and is beginning to resurge in light of more information on menopausal hormone therapy (MHT).

Dr. Rebecca Dunsmoor–Su and Dr. Amy Voedisch mix science, history, and some observations on how medical research has typically treated women to explain how randomized controlled trials and evolving interpretations of data have reshaped our understanding of hormone therapy. And why getting the facts straight matters more than ever.

Whether you're curious about the science, interested in the drama, or just wondering how hormone therapy became so complicated, this episode delivers the goods.

What you'll hear in this episode:

[:45] Intro to Hormone Therapy Series

[5:30] The history of estrogen

[8:32] Hormone therapy on the rise

[13:24] Digging into some research

• observational studies
• randomized control studies

[23:31] HRT as preventive medicine

[25:06] HERS study: HRT and heart health

[31:52] Ethical considerations

[38:14] Coming up in our HRT series

Learn more about the Women's Health Initiative at www.whi.org

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Meet the Docs:

More information about Dr. Rebecca Dunsmoor-Su:

Gennev: www.gennev.com/clinician/dr-rebecca-dunsmoor-su

LinkedIn @rebecca-dunsmoor-su

More information about Dr. Amy Voedisch:

Stanford Medical Clinic: stanfordhealthcare.org/doctors/v/amy-voedisch.html