Huberman Lab

Essentials: How to Build Endurance


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In this Huberman Lab Essentials episode, I explain how to build endurance and describe targeted protocols to enhance different types of endurance.


I discuss how endurance—the ability to sustain effort—requires the coordination of physical and mental systems driven by energy availability, brain willpower, and specific training adaptations in the muscles, heart, lungs and neurons. I explain conditioning protocols designed to enhance four types of endurance, from long-duration steady state to muscular endurance and high-intensity intervals, and how each training style triggers unique adaptations in the body and brain, such as improved mitochondrial function and oxygen utilization. Additionally, I highlight the crucial role of hydration and electrolytes, which are essential for neural function and influence the brain’s willpower to sustain effort.


Read the episode show notes at hubermanlab.com.


Thank you to our sponsors

AG1: https://drinkag1.com/huberman

LMNT: https://drinklmnt.com/huberman

Eight Sleep: https://eightsleep.com/huberman

Function: https://functionhealth.com/huberman


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  • Timestamps

    00:00:00 Huberman Lab Essentials; Build Endurance

    00:00:50 Energy Sources, ATP, Oxygen

    00:04:14 Neurons & Willpower, Glucose & Electrolytes

    00:09:19 Heart, Lungs; Physiology & Performance Limiting Factors

    00:10:35 Sponsor: AG1

    00:12:30 Muscular Endurance, Protocol, Concentric Movements, Mitochondria

    00:19:10 Sponsors: LMNT & Eight Sleep

    00:22:00 Long-Duration Endurance, Efficiency, Mitochondria, Capillaries

    00:25:54 High-Intensity Interval Training (HIIT), Anaerobic Endurance, Protocol

    00:32:33 High-Intensity Aerobic Endurance, Adaptations

    00:35:30 Sponsor: Function

    00:37:26 Brain & Body Adaptations, Heart

    00:40:40 Hydration, Tool: Galpin Equation

    00:42:21 Supplements, Stimulants, Magnesium Malate

    00:43:11 Recap & Key Takeaways


    Disclaimer & Disclosures

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