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Dr. David Perlmutter is a board-certified neurologist, author, and expert in brain health, neurodegenerative diseases, and nutrition. He is best known for his books Grain Brain and Brain Maker, which explore the connection between diet, gut health, and cognitive function. Through his research and public speaking, Dr. Perlmutter advocates for a low-carb, high-fat diet and lifestyle changes to optimize brain health and prevent conditions like Alzheimer's and cognitive decline.
In our conversation we discuss:
(00:00) - Brain Wars
(04:04) - Effects of genetics vs. the choices you make
(09:38) - Major differences in diets
(14:45) - Lifespan vs. longevity among our Paleolithic ancestors
(19:48) - How DNA can affect the diet you're adaptable to
(26:08) - Fat consumption
(31:00) - Difference between taking supplements and getting nutrients directly from food
(38:17) - Widespread use of drugs called GLP-1 agonists
(44:12) - Downsides of GLP-1
(46:14) - Reactive medicine
(48:36) - How to determine your metabolic rate
(54:42) - Where do you get continuous glucose monitoring?
(55:33) - Effects of supplements on the brain
Learn more about Dr. Perlmutter:
https://drperlmutter.com/
https://en.wikipedia.org/wiki/David_Perlmutter
Watch full episodes on: https://www.youtube.com/@seankim
Connect on IG: https://instagram.com/heyseankim
Christian Drapeau is a stem cell scientist, author, and speaker known for his work in adult stem cell research. He popularized the idea of enhancing the body’s natural repair mechanisms and wrote Cracking the Stem Cell Code. Drapeau has also developed plant-based supplements supporting stem cell function, bridging science and wellness.
In our conversation we discuss:
(00:55) - Helping people with stem cells
(05:48) - What are stem cells?
(09:24) - What happens to stem cells as we grow old?
(13:50) - Can stem cells be counted?
(18:37) - Political and philosophical challenges
(20:19) - Stem cell therapy
(27:01) - What are the risks?
(37:00) - Why is there a delay in the effect of the therapy?(39:38) - What natural ways help produce stem cells?
(43:36) - Foods that affect stem cells
(47:10) - Differences in stem cell therapy across countries
(51:09) - Who should look into stem cells?
(53:00) - Stem cells in the next 50 years
Learn more about Christian:
Linkedin: https://www.linkedin.com/in/christian-drapeau
Instagram: @stemcellchristian
Books: https://www.amazon.com/s?i=stripbooks&rh=p_27%3AChristian%2BDrapeau&s=relevancerank&text=Christian+Drapeau&ref=dp_byline_sr_book_1
Watch full episodes on: https://www.youtube.com/@seankim
Connect on IG: https://instagram.com/heyseankim
James Altucher is an entrepreneur, author, and podcast host who has founded over 20 companies. He’s the author of "Choose Yourself" and hosts The James Altucher Show. Altucher is also an advocate for the transformative potential of AI, often discussing its impact on business and personal development in his work and interviews.
In our conversation we discuss:
(00:45) - James' AI experience
(04:49) - What was the first version of AI?
(12:23) - What will be the next bottlenecks in AI?
(19:21) - Quantum computers
(23:29) - Which jobs can be easily replaced by AI?
(32:00) - AI’s limitations in judgment
(38:38) - Human vs. AI interactions
(42:52) - Appreciating human creativity
(46:37) - What skills do humans need to unlearn?
(58:56) - James as a chess master and comedian
(1:03:25) - Taking more risks
(1:07:02) - What are the positive risks and challenges with AI?
(1:11:40) - The Lindy Effect
(1:14:48) - Keeping up with technological advancements
(1:18:53) - Opportunities that come with AILearn more about
James:Podcast: The James Altucher Show - https://jamesaltuchershow.com/Website: https://www.jamesaltucher.com/
Watch full episodes on: https://www.youtube.com/@seankim
Connect on IG: https://instagram.com/heyseankim
Moran Cerf is a neuroscientist and professor at Northwestern University, specializing in decision-making and consciousness. His research blends neuroscience, psychology, and AI to explore how humans make choices. A former hacker, he also studies the intersection of brain science and technology. Cerf is a sought-after speaker at events like TED and the World Economic Forum. His work has gained recognition in both academia and popular science.In our conversation we discuss:(00:00) - Introductions
(0:40) - Emotional regulation
(5:50) - Having a second person that listens
(8:37) - Chasing the story in your brain
(10:17) - Exposures
(12:35) - Embodied cognition
(17:35) - Smell or odor
(25:29) - Purpose of tears
(29:01) - Being in a neutral place
(31:59) - Major histocompatibility complex
(33:29) - Magic pheromones
(38:32) - Signaling emotions
(42:18) - Persuasion
(52:59) - Negotiation
(1:00:26) - Being likable
Learn more about Moran CerfOfficial Website: https://www.morancerf.com/Linkedin: https://www.linkedin.com/in/morancerfInstagram: https://www.instagram.com/morancerf
Watch full episodes on: https://www.youtube.com/@seankim
Connect on IG: https://instagram.com/heyseankim
Sahil Bloom is an entrepreneur, investor, and writer known for his insightful takes on personal growth, business, and life. He gained significant attention through his thought-provoking threads on X (formerly Twitter), where he shares wisdom on topics like mental models, productivity, and navigating the challenges of building a successful life and career. With a background in finance and entrepreneurship, Sahil has worked with top-tier companies and has been an advocate for creating meaningful and intentional success. Through his content, he aims to inspire others to think critically, take action, and design a life that aligns with their values.
In our conversation, we discuss:
(0:56) - Small things become big things
(4:02) - Consistency
(7:49) - The real race
(9:40) - Validation from others
(17:11) - The harder path
(21:10) - Time billionaire
(27:26) - What is enough money
(29:31) - Assessing opportunities
(32:09) - Tim Cook as Sahil’s mentor
(36:28) - Permission
(38:03) - Reframing Impostor Syndrome
(40:46) - Confronting true failure
(44:52) - Goal inversion
(50:36) - Importance of space
(52:11) - Harvard Study of Adult Development
(55:50) - Walking the walk
(58:20) - View on therapy
(1:00:00) - What’s a question you ask yourself regularly?
(1:04:04) - Your own path
Learn more about Sahil:
Sahil Bloom's X (formerly Twitter): @Sahil_Bloom
Sahil Bloom's Instagram: @Sahil_Bloom
Book: https://www.amazon.com/gp/product/059372318X?tag=randohouseinc7986-20
Watch full episodes on: https://www.youtube.com/@seankim
Connect on IG: https://instagram.com/heyseankim
Don Saladino is a celebrity fitness trainer, entrepreneur, and wellness expert known for transforming Hollywood actors into superhero shape. With over two decades of experience, he has worked with stars like Ryan Reynolds, Hugh Jackman, and Blake Lively. Don specializes in strength training, functional fitness, and sustainable health practices, emphasizing longevity over quick fixes. He is also the founder of the fitness platform Playbook and shares expert insights on social media, podcasts, and online programs. His holistic approach integrates training, nutrition, and mindset to help clients achieve peak performance.
Instagram: instagram.com/donsaladino
Facebook:facebook.com/saladinodon
X (Twitter): x.com/donsaladino
TikTok: tiktok.com/@donsaladino
Watch full episodes on: https://www.youtube.com/@seankim
Connect on IG: https://instagram.com/heyseankim
Wim Hof, also known as "The Iceman," is a Dutch extreme athlete renowned for his extraordinary ability to withstand extreme cold. He created the Wim Hof Method, which combines breathing techniques, cold exposure, and meditation to enhance physical and mental performance. His feats include running a marathon above the Arctic Circle in shorts and shoes and holding the world record for the longest ice bath. Hof’s method has gained global recognition for its potential to improve health, reduce stress, and increase overall well-being.
In our conversation, we discuss:
(00:00) - Humans can battle anything
(03:35) - Why did Wim Hof choose cold and breathing?
(14:04) - Overcoming your mind
(18:10) - A cold shower a day keeps the doctor away
(23:33) - How to remain peaceful in a stressful situation
(29:04) - Brown fat
(38:52) - Cold is a great teacher
(42:44) - Wim’s advice: "Take the damn cold shower!”
(48:40) - Cold can help our moods
(50:28) - Benefit of heat
(55:12) - Difference between sauna and cold showers
(1:02:12) - Breathing
(1:07:00) - Rebalancing the hormonal system to aid depression
(1:12:27) - Regain control
(1:17:18) - How do you look at death?
Learn more about Wim Hof:
https://www.instagram.com/iceman_hof
https://www.wimhofmethod.com/
Watch full episodes on: https://www.youtube.com/@seankim
Connect on IG: https://instagram.com/heyseankim
Vanessa Van Edwards is a behavioral investigator and the founder of Science of People, a research lab focused on human behavior. She is the author of the best-selling book Cues: Master the Secret Language Communication and has been featured in The New York Times, Forbes, and TEDx. Through her courses, workshops, and speaking engagements, Vanessa helps individuals and organizations improve their social skills, communication, and professional success of Charismatic.
In our conversation, we discuss:
(00:00) – Sean and Vanessa’s Catch-up
(01:00) – Personalities and Communication Styles
(05:47) – Neuroticism
(12:24) – Distinction Between AI and Humans in Conversations
(17:59) – Warmth of Communication and Competence
(20:30) – In-person Conversations
(25:27) – Scent
(33:26) – Reading Signals for Trust
(51:39) – Improving Self-talk
(59:06) – Vanessa’s Book
(1:06:51) – Conversation Cues
(1:28:13) – Online Dating
(1:37:00) – Physical Dating
(1:48:00) – Approaching Someone You Don’t Know
(1:54:54) – People Skills Can Be Taught
(2:01:09) – First Impressions
(2:12:47) – Silence
Learn more about Vanessa:
https://www.scienceofpeople.com
https://www.instagram.com/vvanedwards
Watch full episodes on: https://www.youtube.com/@seankim
Connect on IG: https://instagram.com/heyseankim
Dr. Mark Hyman is a renowned physician, bestselling author, and leading voice in functional medicine. As the founder of The UltraWellness Center and a senior advisor for the Cleveland Clinic’s Center for Functional Medicine, he focuses on addressing the root causes of chronic disease. Dr. Hyman has authored numerous bestselling books on health and nutrition, including Food Fix and The Pegan Diet, and is a passionate advocate for food as medicine. Through his work, he empowers individuals to achieve optimal health through personalized and holistic approaches.
In our conversation, we discuss:
(00:46) - Dr. Hyman’s Opinion on Longevity
(09:13) - Functional Medicine
(10:30) - Reversing Biological Age
(16:22) - Anabolic Resistance
(18:00) - Dr. Hyman’s Fasting
(18:52) - Metformin
(20:54) - Longevity Switches
(23:00) - Mitochondria Health
(25:00) - Metabolic Health
(27:24) - Reference Ranges
(29:37) - What Are the Most Important Tests We Can Request For
(34:07) - Growing Cancer Rate
(37:44) - American Diet Problem
(38:50) - Epigenetic Changes
(40:40) - Exposome
(42:05) - Ultra-Processed Foods
(45:20) - Principles
(45:50) - Superfoods
(53:10) - Testosterone’s Impact on Longevity
(55:10) - Fats
(55:32) - Personalized Medicine
(57:35) - Fluoride Levels
(1:00:18) - Functional Health
Learn more about Dr. Hyman:
https://drhyman.com/
GET EARLY ACCESS TO FUNCTION!
Act fast—spots are limited!
Watch full episodes on:
https://www.youtube.com/@seankim
Connect on IG:
https://instagram.com/heyseankim
Gin Stephens, a New York Times bestselling author, is known for her books Delay, Don’t Deny and Fast. Feast. Repeat., which promote intermittent fasting. Her latest book, 28-Day Fast Start Day-by-Day (2023), offers practical guidance for starting or recommitting to fasting. She also hosts the podcast Intermittent Fasting Stories, sharing real-life success stories. Stephens inspires a global audience to embrace health through sustainable lifestyle changes.
(00:00) - Introductions
(00:43) - Gin’s story
(04:09) - Other things you tried
(08:12) - What are the things that you will not recommend
(12:12) - What are your thoughts on diet pills
(17:12) - Our body signals
(18:05) - Intermittent fasting
(26:30) - What are the differences between the time windows
(29:43) - Bio-individuality
(32:40) - Habits
(35:28) - Prolonged fasting
(43:00) - Autophagy
(48:45) - Therapeutic fasting
(52:35) - Undereating and over-exercising
(55:00) - Listen to your body
(57:40) - Biomarkers
(1:01:21) - Fasting clean
(1:07:25) - Principles
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