Tim Egan is a Pulitzer Prize–winning journalist, National Book Award–winning author, and longtime New York Times columnist who publicly challenged the media narrative around Amanda Knox’s case when few others would. In this episode, Amanda and Tim unpack how predatory journalism, cultural bias, and economic incentives fuel rushes to judgment, how misinformation erodes our ability to agree on basic facts, and why truth telling becomes harder and more necessary when narratives turn tribal. They also explore why history offers both warning signs and hope, and how ordinary individuals can still bend the arc toward justice.

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Lauren Weedman is an Emmy-nominated writer, comedian, and actor known her roles in HBO’s Looking, Hung and Hacks. She is also a renowned solo performer whose work is built on fearless honesty and dark humor. In this episode, Lauren gives Amanda a candid masterclass in solo storytelling, from why audiences hesitate to laugh at trauma, to how musical numbers, silence, and even a well timed cartwheel can unlock tension onstage. Along the way, they trade unforgettable moments about prison mugshots, shame, loneliness, and how a mother can balance the intense energy of a theatrical run with the demands of family life.

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Warren Littlefield is an award winning television producer and former NBC network president whose career spans landmark shows from Cheers to The Handmaid’s Tale and The Twisted Tale of Amanda Knox. In this candid and behind the scenes conversation, Warren and Amanda revisit the making of the series together, sharing stories about freezing fog in Vancouver, impossible production schedules, and the tiny details like suitcases and pastries that carry enormous emotional weight. Along the way, Warren reflects on firefighting in the entertainment industry, replacing Johnny Carson, embracing change, and why protecting creative vision, listening to your gut, and questioning official narratives matter far beyond television.

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In this Ask Amanda Anything episode, Amanda and Chris tackle big, tender questions about career pivots, privacy, creativity, and what it means to live openly without losing yourself. They share raw and funny stories about quitting “soul sucking” jobs, being the first person on the dance floor, and relearning joy after it was taken away. The conversation moves from Taoist ideas about following life’s current to the ethics of oversharing, offering a look at how curiosity, connection, and courage help us begin again.

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Maya Shankar is a cognitive scientist, writer, and host of the podcast A Slight Change of Plans, whose new book The Other Side of Change explores who we become when life takes an unexpected turn. In this rich and intimate conversation, Maya and Amanda dig into moments ranging from Juilliard dreams cut short by injury to miscarriage. They talk about locked-in syndrome, prison poetry, and the surprising psychology of why uncertainty can feel worse than pain. Along the way, Maya shares practical tools offering listeners a hopeful and deeply human guide to navigating change without platitudes.

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In a moment when the news feels relentless and outrage is often treated as a moral obligation, Amanda reflects on what meditation is really for. Is sitting quietly a form of disengagement, or a way of learning how to respond without making things worse? Drawing on Zen practice, Buddhist history, and her own experience of trauma, activism, and family life, Amanda explores the false choice between rage and withdrawal, and makes the case for tending the quality of our own minds as a prerequisite for meaningful engagement. In a world on fire, this is an argument for care, clarity, and action that doesn’t multiply harm.

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Mike Semanchik is the executive director of the Innocence Center, and Scott McMahon is an American who spent more than five years imprisoned in the Philippines for a crime he did not commit. In this episode, Amanda, Mike, and Scott unpack how a justice system built on delay, corruption, and extortion can turn a single accusation into a life sentence without a verdict, how patience and tenacity become survival skills when truth is systematically ignored, and why refusing to pay for freedom can cost everything and still be worth it.

Michael Semanchik is also the host of the podcast For The Innocent, where he tells the stories of those who have been unjustly imprisoned and the tireless efforts to bring them home.

Read more about Scott's case here https://theinnocencecenter.org/case/scott-mcmahon/

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In this episode of Hard Knox, Amanda is joined by her husband Chris for an intimate and surprisingly funny conversation about the practice of beginning again. Drawing from Zen practice, a New Year’s fight, and a walk in the woods, they explore how noticing momentum in our thoughts, moods, and arguments can interrupt downward spirals, how compassion and physical connection can reset conflict, and why beginning again is not about erasing the past but choosing wisely in the present.

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Scott Barry Kaufman is a cognitive scientist and bestselling author whose work explores creativity, intelligence, and what helps people grow after hardship. In this episode, Amanda and Scott talk about how we get stuck in stories about ourselves, how to tell the difference between honoring pain and letting it run the show, and why growth often starts with a small shift in perspective rather than a dramatic breakthrough. Along the way, they explore why curiosity beats self judgment, how hope can be learned, and why becoming more whole does not require erasing what you have been through.

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Amanda and Chris debate the true meaning of Christmas through stories about Charlie Brown, gift giving, religion, pagan traditions, and very strong opinions about gift cards. They explore why Christmas has always been less about belief and more about gathering, why remembering people matters more than buying things, and why sharing your blueberries might actually be the whole point.

Reach out to us at ⁠⁠⁠⁠⁠⁠www.amandaknox.com⁠⁠⁠⁠⁠ ⁠or ⁠⁠⁠⁠⁠⁠amandaknox.substack.com⁠⁠⁠⁠⁠⁠

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