💬 “ We already know the biggest levers. Nutrition, sleep, movement, connection, sunlight—all of those things we've known about for decades and they're not sexy, but they work. Even novel gadgets are just an add-on to these big buckets." ~ Dr. Karan Rajan

➡ In this episode, host Tim Gray sits down with NHS surgeon and social media phenomenon Dr. Karan Rajan to navigate the complex world where mainstream medicine meets online wellness culture. Dr. Karan shares his long history of making educational content and his mission to provide nuanced, evidence-based knowledge in a digestible format. Together, they dive deep into the tension between established medical practice and the biohacking movement, exploring how to remain grounded in science while staying open to innovation. Listeners will come away with a refreshing, balanced perspective on health optimization and the tools to separate science from fiction.

💡 Highlights

(0:00) Intro

(1:09) Welcome to Dr. Rajan

(1:12) Why an NHS Surgeon Started Making TikToks

(6:46) Why a Degree Doesn't Mean Someone is Always Right

(11:07) Bridging Mainstream Medicine and the Wellness World

(16:48) The "Big Levers" of Health vs. The Extra 1% from Biohacking

(20:47) The Dangers of Over-Supplementation & Protecting Your Liver

(26:48) Dr. Karan Reveals the Supplements He Personally Takes

(33:04) Mouth Taping: An Updated, Nuanced Stance

(44:06) A 3-Phase Plan to Support Your Gut Through Antibiotics

(52:44) Fiber vs. Fibers: Why Diversity is the Key to Gut Health

(56:24) The Debate on Blue-Blocking Glasses

(59:59) An Honest Take on Hydrogen Water

(1:03:51) Rapid Fire: Harmful Trends, Fixing the NHS, and Biggest Health Wins

Follow Dr. Karan Rajan for more evidence-based health education:

Instagram: https://www.instagram.com/drkaranrajan/ 

TikTok: https://www.tiktok.com/@dr.karanr 

YouTube: https://www.youtube.com/@DrKaran/videos 

Massive thank you to OMNi-BiOTiC for sponsoring this episode!

Most people think detox starts with your liver - but it actually begins in your gut. If your gut barrier is weak, your liver gets overloaded, fast. That’s why I’ve added OMNi-BiOTiC HETOX to my morning routine. It’s a probiotic powder delivering 15 billion bacteria from 9 scientifically tested strains, specifically selected to tighten your gut lining, balance cholesterol, and reduce the toxic load on your liver. The sachets are super easy to take, and it’s free from gluten, yeast, lactose and animal protein. Since taking it, I’ve noticed better digestion, clearer mental focus, and more consistent energy levels.

If you’re interested in detox, energy, or metabolic health, visit http://shop.omni-biotic.com and use code TIM for 20% off to give your gut the upgrade it deserves.

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⚡️Female-specific health protocols, groundbreaking therapies, & the secrets to thriving in your prime years.

💬 “ Women weren't required to be included in medical research until the early 1990s, which is about the same time I was born.” - Kayle Barnes

➡︎The Evolving Role of Women in Biohacking: Despite statistics indicating that the community is predominantly male, Tim and Kayla express optimism about the evolving status of women. 

➡︎Fertility and Environmental Toxins: A Growing Concern: With lifestyle and environmental factors accounting for up to 50% of infertility cases, this episode explores the critical biohacks and diagnostics women should consider to preserve their fertility. 

➡︎The Power of Creatine: Not Just for Men: Creatine, traditionally associated with muscle growth and performance in men, is hailed as a game-changer for women as well. 

➡︎Emerging Therapies and Controversial Treatments: Treatments like Hyperbaric Oxygen Therapy (HBOT), plasmapheresis, and emerging European innovations like in-use pheresis are gaining traction for their potential benefits.

➡︎ Kayla is the CEO and Co-Owner of LYV The Wellness Space, which is one of the most innovative precision medicine and biology upgrading clinics in the country. Kayla is also the creator and host of the Brain Biohacking Podcast and co-founder of the Health Optimization Fund. She completed coursework and is certified by the Amen Clinics for Brain Health and IIN for Integrative Nutrition.

💡 Highlights

(0:00) Intro

(1:09) The Role of Women in Biohacking

(2:15) Challenges and Evolution in Female Biohacking

(5:10) Hyperbaric Oxygen Therapy and Its Growth

(7:24) Publishing Personal Health Data

(14:12) Female-Specific Health Protocols

(23:09) Menopause and Hormone Replacement Therapy

(29:09) Fertility and Environmental Toxins

(37:23) Innovations in At-Home Health Testing

(38:44) Vaginal and Oral Microbiome Insights

(43:24) Brain Health and Stress Management

(49:55) Emerging Therapies and Controversial Treatments

(55:49) The Power of Creatine and Female Supplementation

(58:56) Top Biohacks and Longevity Tips

(1:06:19) Final Thoughts and Farewell

🔎 Visit: https://www.kaylabarnes.com and https://www.instagram.com/kaylabarnes/

A big thank you to Timeline Longevity for sponsoring this episode!

I’ve been taking Mitopure for years now - it’s the only clinically proven form of Urolithin A, a compound that recharges your cellular energy by restoring your mitochondria (those tiny powerhouses inside your cells). It’s been developed over 15 years with the Swiss Federal Institute of Technology, and it works. Since taking it, I’ve noticed stronger workouts, faster recovery, and sustained energy.

Now it comes in a clean, sugar-free gummy (naturally sweetened with stevia) - vegan, gluten-free and non-GMO. Same powerful science, even easier to take.

If you want to stay strong and energised now and as you age, head to https://timeline.com/TIMBIOHACKER, or use the code TIMBIOHACKER for 20% off your first order. Trust me, your cells will thank you!

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⚡️Tim shares his favourite biohacks, including cellular health, proper hydration, the power of grounding and much more. 

💬 “ Biohacking for me is optimizing your health, not about chip implants, not about all of these crazy changes to your body. It is about being the best version of you using nature, science and technology where relevant. ” - Tim Gray

➡︎Today’s episode features Tim in a different light – he’s sharing a live recording of his main stage talk from the Health Optimisation Summit in Austin! 

➡︎Since the feedback on his talk was overwhelmingly positive, whether you were there or not, this episode brings Tim’s insights to everyone.

➡︎Packed with practical takeaways, and an audience Q&A, Tim dives into some of the biggest lessons he’s learned about health, longevity, and, most importantly, motivation. 

➡︎Tim emphasizes that knowing what to do is just the first step; feeling inspired to take action is key!

➡︎In his talk, Tim covers a variety of topics, including blood glucose and HRV tracking, gut health, community, sleep, and the vital role of emotional connections in recovery and long-term vitality. It’s not just about the tech and biohacks – it’s about how to implement them in real life.

🔎 Visit the London Health Optimisation Summit on 13-14 September - https://uk.healthoptimisation.com/

💡 Highlights

(0:00) Intro

(2:35) Defining Biohacking and Health Optimization

(3:25) Key Principles of Health Optimization

(3:56) The Role of Detoxification

(4:45) Personal Experiences and Lessons Learned

(5:19) The Importance of Personalization in Health

(5:54) Tracking and Quantifying Health

(6:45) Community and Mission

(8:30) Cellular Health and Biohacks

(16:36) Travel and Health Tips

(29:40) Q&A Session

Resources mentioned in this episode can be found at https://podcast.healthoptimisation.com

⚡️ Disclaimer: https://podcast.healthoptimisation.com/disclaimer/

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💬 “ Oh, I'd love to be able to do a venison stew that's been marinating for hours and hours, and I've grown my own potatoes, and there's no glyphosate on it. It's not gonna frigging happen.” - Davinia Taylor

➡︎ Davinia Taylor discusses her personal health journeys, biohacking techniques, and the importance of connection for wellness. She also discusses quality supplements, hormonal imbalances, and maintaining mental and physical health amidst busy lives.

✚Plus:

➡︎Challenges of Modern Living

➡︎Questioning Traditional Health Narratives

➡︎The Impact of Hormones and Nutrition

➡︎Practical Tips for Everyday Health 

💡 Highlights

(0:00) Intro

(3:25) Health Hacks & Ketones

(4:31) Sleep Quality & EMF Concerns

(6:06) New Book: Future Proof

(7:29) Challenging Mainstream Health Advice

(13:28) Importance of Sunlight

(18:28) Blue Light & Sleep

(29:35) Genetics & Epigenetics

(38:58) State of Modern Medicine

(42:11) Big Pharma and Biohacking

(43:25) The Convenience of Supplements in Modern Life

(50:10) Parenting Challenges &Health Awareness

(58:03) Hormonal Balance & Everyday Toxins

(1:06:57) Importance of Connection and Community

🔎 Visit: https://www.willpowders.com & https://www.instagram.com/daviniataylor/ 

Check out Davinia’s brand new book ‘Futureproof’: https://www.amazon.co.uk/Futureproof-Build-Resilience-Younger-Longer/dp/1398709654/ref=tmm_pap_swatch_0

➡︎ Mythos Skincare (Men and Women): https://mythosmen.com/collections/mythos-men

Swanwick Blue Blocking Glasses: https://www.swanwicksleep.com/products

➡︎ Fussy deodorant - https://www.getfussy.com/?srsltid=AfmBOopSnRvuJJ5gvNeVaW3O3KT6oC1Koxr9lHl-_i4jbatR7NSRncTj

➡︎ Swanwick blue blocking glasses - https://www.swanwicksleep.com/'

If you want to hear more from Davinia, catch her speaking at the London Health Optimisation Summit on 13-14 September - https://uk.healthoptimisation.com/

Massive thank you to Hume for sponsoring this episode!

Stop guessing and start tracking what matters. The Hume Body Pod gives you hospital-grade body composition insights, including visceral fat, skeletal muscle mass, body fat %, and hydration, in under 60 seconds, right from your home. It’s 98% as accurate as a DEXA scan, without the hassle, cost, or wait time. You’ll also get weekly health reports, metabolic insights, and progress tracking to dial in your training, nutrition, and recovery with confidence.

Visit https;//humehealth.com and use code TIMBIOHACKER for 20% off your Body Pod!

⚡️ Disclaimer: https://podcast.healthoptimisation.com/disclaimer/

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⚡️The hidden dangers of everyday toxins, and how to adopt a non-toxic lifestyle.

💬 “ Our ancestors were never exposed to this amount of toxins, and our bodies don't know how to deal with them.” - Warren Phillips

➡︎Your Home Might Be More Toxic Than the Highway: Discover why the air inside your house could be 5x more polluted than the smog outside—thanks to carpets, furniture, and building materials.

➡︎$15 Hack to Clean the Air You Breathe: Learn the clever, dirt-cheap DIY air filter trick that could seriously reduce toxins in your home—using just a box fan and one key upgrade.

➡︎Hidden Toxins in Your "Clean" Routine: Shockingly, your fresh-smelling laundry and sparkling dishes might be leaving behind chemical residues that mess with your hormones and immune system.

➡︎How to Detox Without Losing Your Mind: Forget going full crunchy overnight—Warren shares a sane, step-by-step strategy to reduce everyday toxins without flipping your whole life upside down.

➡︎ Warren’s mission is to help others achieve healthy and happy toxin-free living. He believes that toxins should be “canceled” and that everyone can live healthier by making simple changes to their daily routines. As a father, he understands the importance of teaching children how to live toxin-free lives. He has made it his goal to educate families on the dangers of toxins and the benefits of a toxin-free lifestyle.

➡︎ In this eye-opening episode, Warren Phillips uncovers why the air inside your home is likely more toxic than you think—and what you can do about it. He exposes hidden health threats in "clean" products like laundry detergent and dishwasher tabs, reveals a dirt-cheap DIY air filter hack, and explains why chemical exposure is skyrocketing globally. Plus, Warren shares his personal frustrations with the medical system and offers a sane, step-by-step guide to ditching toxins without losing your mind. If you’ve ever wondered how you can clean up your daily routine, stick around to the end of the episode for our rapid fire round!

💡 Highlights

(0:00) Intro

(0:14) Introduction

(0:21) The Hidden Dangers of Household Products

(3:49) Fear-Mongering or Awareness?

(5:24) The Challenges of Promoting Health

(12:13) Five Pathways of Toxic Exposure

(16:41) Frequency and Light Quality

(22:26) Indoor Air Quality Concerns

(25:33) The Problem with Building Materials

(29:38) A Cleaner Alternative

(37:55) The Dangers of Dishwasher Tablets

(42:56) Laundry Detergent Risks

(49:00) The Cosmetic Chemical Crisis

(55:34) Quick Fire Health Hacks

(1:00:56) Conclusion and Call to Action

🔎 Visit: https://nontoxicdad.com 

A huge thank you to DIP for sponsoring this episode!

Most people don’t realise their cleaning products are loaded with hormone disruptors, gut-wrecking compounds, and chemicals that end up on your skin, your food, and in your lungs. It’s honestly shocking what the big brands get away with. That’s why I switched to DIP - they’ve stripped out all the nasty stuff, but the cleaning power’s still there. Laundry sheets, dishwasher sheets and multi-purpose spray - it’s all I use at home now. Head to https;//wearedip.co.uk and use code TIMBIOHACKER for 15% off your first order.

⚡️ Disclaimer: https://podcast.healthoptimisation.com/disclaimer/

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⚡️Everything we’ve got wrong about cancer - and how to actually protect yourself

💬 “ Cancer is not the enemy, it's the messenger. And it's trying to tell you that there's a lot of things that are outta balance in the world around you” ~Nasha Winters

➡︎ We’ve been waging war against cancer for a long time, trying to fight it, cut it out and treat it as the enemy. But what if we took a different approach? What if we saw it as a messenger, telling us that something is wrong inside our bodies - and we need to take a closer look?

➡︎ Dr Nasha Winters is an integrative oncology specialist, using her own experiences of cancer to help conventional oncologists do their job better. Nasha was diagnosed with stage 4 ovarian cancer aged 19 and was told she only had a few months left to live. Despite that, she managed to recover and has been on a journey to help others like her ever since. 

➡︎ In this episode, Nasha and Tim discuss everything we have wrong about cancer, from the root causes driving the boom in cancer rates, to the mindshift change we need to make when approaching cancer treatment. They explore why traditional medicine is not enough on its own to actually heal us from cancer - and why a biohacker’s approach is often needed. And they discuss holistic healing strategies, like fasting, that have helped many of Nasha’s patients over the years.

💡 Highlights

(1:36) Nasha’s cancer diagnosis

(10:19) Accidental fasting to beat cancer

(15:05) What is an integrative oncologist?

(19:30) What does “curing” cancer really mean?

(26:14) What have we got wrong about cancer?

(29:53) Why we shouldn’t be waging war on cancer

(34:14) How lifestyle influences cancer

(43:09) A biohacker’s place in medicine

(49:19) What does Nasha’s treatment protocol look like?

(52:49) The 10 root causes of cancer

(58:59) Where medicine and integrated health can work together

(1:01:49) The major mindset shift we need around cancer

🔎 Visit: https://www.instagram.com/drnashawinters/ 

Find Nasha’s book: https://amzn.eu/d/ckS6YDg 

A huge shoutout to Oxford Healthspan for sponsoring this episode!

As we age, our spermidine levels naturally decline, making it harder for our cells to repair and renew. That’s where Primeadine comes in - Oxford Healthspan’s supplement that delivers 1mg of bioavailable spermidine in every capsule, plus prebiotic fiber to boost your body’s natural production. I’ve been using Primeadine, and it’s made a noticeable difference in my energy, sleep, cognition, gut health and hormonal health. It’s pure, plant-based, and free from fillers. To restore those optimal spermidine levels, head to https://oxfordhealthspan.com/ and use code TIMBIOHACKER for 15% off!

⚡️ Disclaimer: https://podcast.healthoptimisation.com/disclaimer/ 

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⚡️Embrace natural lifestyle changes that create optimal vision and overall eye wellness.

💬 “Glasses don’t really correct anything; when you take them off, your vision is usually worse than it was before.” ~Claudia Muehlenweg

➡︎ Glasses vs. Natural Vision: Discussion on how traditional corrective lenses can mask underlying issues rather than address the root cause.

➡︎ Eye Mechanics: Explanation of saccadic eye movements, blinking habits, and the importance of natural eye movement for clarity.

➡︎ Lifestyle Hacks: Simple practices like blinking exercises, proper breathing techniques, and getting natural sunlight to boost eye health.

➡︎ Controversial Insights: Debate on the role of sunglasses, the impact of technology on our vision, and how modern habits may be contributing to a global rise in myopia.

➡︎ Mind-Body Connection: Exploration of how stress, diet, and even neck tension can influence our eyesight and overall brain health.

➡︎ In this episode, host Tim Gray sits down with Claudia Muehlenweg to explore the hidden truths behind our conventional reliance on glasses and contacts. Claudia shares her personal journey—from being teased as a child for wearing glasses to discovering the natural techniques that improved her vision. Together, they dive deep into the mechanics of eye movements, the importance of natural light, proper blinking, and lifestyle habits that support eye health. The conversation also touches on controversial topics like the effects of sunglasses and screen time on our eyes, linking eye health to overall wellness and even brain function. Listeners will come away with actionable tips and a fresh perspective on maintaining sharp, natural vision without solely relying on corrective lenses.

🔎 Join Claudia Muehlenweg for a Zero-Cost 4-day vision improvement training! - See Better in Just 4 Days. https://naturallyclearvision.com/go/health-optimisation

💡 Highlights

(0:00) Intro

(3:00) Claudia’s Early Experiences & Journey

(5:00) The Problem with Conventional Eyewear

(8:00) Understanding Eye Mechanics

(12:00) Lifestyle & Behavioral Strategies

(17:00) Natural Light & Environmental Influences

(22:00) Diet, Nutrition & Eye Health

(28:00) Eye-Brain Connection & Cognitive Insights

(37:00) Future Trends in Vision Health

(43:00) Practices You Can Start Using Today

🔎 Visit: https://naturallyclearvision.com 

🔎 10 Habits for Healthy & Happy Eyes: https://discover.naturallyclearvision.com/10habits

A huge thank you to Hinnao Technology for sponsoring this episode!

Their liposomal NAD+ and Glutathione have completely transformed my approach to energy and detox support. They're super clean and incredibly easy to take—just a few drops under the tongue with instant absorption that you’d normally need an IV for. When I travel, I always bring their glutathione for detox support and NAD for energy.

Hinnao is undoubtedly one of the best brands out there, offering unmatched bioavailability and pharmaceutical-grade active ingredients. Check them out at https://hinnao.com/ and use code TIMBIOHACKER for 15% off all their products.

⚡️ Disclaimer: https://podcast.healthoptimisation.com/disclaimer/ 

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⚡️Feeling frustrated? Racing mind? Try this.

💬 “ If the whole world actually meditated, the world that we live in would be a kinder, better place.” ~Ariel Garten

➡︎ Meditation is a practise we all know we should be doing, but aren’t. Often it’s not for lack of trying - meditation can be hard, and in a world where we’re taught to be busy at all times, it can feel like a waste of time. But meditation is the key to unburdening yourself from stress, anxiety, trauma and self-doubt. Luckily, there’s a way to make it easier.

➡︎ Ariel Garten is a neuroscientist and co-founder of Muse, a healthtech startup that has created a brain-sensing EEG headband that is helping over half a million people around the world improve their meditation practises. By measuring your brainwaves while you meditate, Muse gives you real-time biofeedback on brain activity, heart rate, and body movements. Ariel and Muse have been featured in the likes of Forbes, Fortune, Men’s Health, Wired and more.

➡︎ In this episode, Ariel and Tim discuss what exactly is going on inside the brain while we meditate - and the science behind why it’s so effective at improving sleep and reducing stress. Ariel explores powerful moments where her meditation practice had a real impact on her life, helping her to unplug from addictions and stop sweating the small stuff. And she explores various meditation techniques and practices - and how you can incorporate them into your life.

💡 Highlights

(1:20) How Ariel’s passion for meditation began

(9:59) What’s going on inside the brain during meditation?

(11:59) Decreasing stress and cortisol

(18:59) How meditation improves attention and focus

(22:54) Your brain waves on meditation

(29:32) Unplugging from addiction

(38:21) Why you should measure your brain waves

(42:28) The impact of diet on your brain

(45:37) Can meditation help us deal with trauma?

(49:17) The different types of meditation

(53:17) How meditation influences pain

(55:06) You don’t need an “empty” mind

(51:15) How Muse is used by pro athletes

(57:41) Advancements in AI and neurotechnology

🔎 Visit: https://www.instagram.com/ariels_musings/

https://choosemuse.com/ 

A huge thank you to MUSE for sponsoring this episode!

Getting results from meditation can be slow - Your meditation app might tell you to focus, but it has no idea what's actually happening in your brain or with your neurotransmitters.Muse neurofeedback shortcuts this. By using advanced EEG sensors to track your brain activity, heart rate and movement in real-time, it’s actually tracking how your body and mind are responding to meditation. When your mind is calm, you hear soothing nature sounds. When it wanders, the sounds shift - it basically sees what's going on inside your brain in real time. For me, this has helped me create a calm, focused mediation practice in days rather than months. If you want to take your meditation practice to the next level and train your brain in real time visit https://choosemuse.com/TIMBIOHACKER for 15% off your Muse headband.

⚡️ Disclaimer: https://podcast.healthoptimisation.com/disclaimer/ 

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⚡️Easy ways to go paleo, live primal and add years to your life - without restriction

💬 “ The essence of the primal movement is, when in doubt, go back to the ancestral model and emulate that in the real world.” ~Mark Sisson

➡︎ The modern world and all its comforts are causing us pain and making us sick. Our bodies did not evolve to live like this - to sit for hours on end, or to chug down ultra-processed food every 3 hours. The solution? Go primal.

➡︎ Mark Sisson is widely known as the founding father of the ancestral health movement and the paleo diet. His focus is on getting us to eat and move like our ancestors, to extend the healthy years we have on this planet. He’s the author of The Primal Blueprint, The Keto Reset Diet and The Primal Connection. And his latest book is titled Born To Walk.

➡︎ In this episode, Mark and Tim discuss the core tenants of the Primal Blueprint, and how you can easily incorporate these into your life. They dismantle the misconceptions around the Paleo diet, explaining just how abundant your food choices can be. They discuss the many health benefits of going barefoot (or wearing barefoot shoes). And, with the Health Optimisation Summit in Austin coming up, they explore the importance of finding your “tribe” and sharing your journey with other, like-minded people.

💡 Highlights

(1:49) Why paleo is THE way to live

(5:03) What our ancestors did better

(13:59) Core tenants of the Primal Blueprint

(18:41) How to achieve metabolic flexibility

(31:17) What can you eat on the paleo diet?

(39:47) Is alcohol ok on paleo?

(46:16) Finding your purpose

(51:17) Benefits of going barefoot

(59:59) Finding your tribe

(1:05:08) A primal vacation

🔎 Visit: https://www.instagram.com/marksissonprimal/ 

A huge thank you to Ape Nutrition for sponsoring this episode!

If you’re tired of protein powders filled with chemicals and fillers, check out APE’s Beef Protein Isolate. With just 5 clean ingredients – grass-fed beef protein, raw cacao, maple, sea salt, and vanilla – it's dairy-free but not plant-based! It's packed with 9 essential amino acids and naturally occurring creatine to support your muscle growth and recovery. Head to www.apenutrition.co.uk and use code TIMBIOHACKER for 10% off your first order.

⚡️ Disclaimer: https://podcast.healthoptimisation.com/disclaimer/ 

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