Podcast Notes Key Takeaways

• Autophagy is the process by which cells (or cellular components) eat themselvesunder conditions of nutrient deprivation (AKA fasting)
  • The dysfunctional cells (like cancer cells) or dysfunctional cell components tend to be “eaten” first
• Autophagy is tissue specific – it’s not an on/off phenomenon 
  • There’s probably some basal or static levels of autophagy occurring in pretty much every tissue of the body in most individuals (most of the time)
• Exercise is one of the best ways to enhance autophagy – how so?
  • Research dictates that in skeletal muscle, autophagy related proteins are present in higher amounts after 12, 24, and 36 hours of fasting in lean/trained people compared to overweight individuals 
    • (In simple terms – this indicates people who exercise frequently may start undergoing autophagy in a shorter amount of time during a prolonged fast)
• Research seems to indicate the more insulin sensitive you are the more readily you can enhance autophagy
• How long do you need to fast in order to increase autophagy significantly?
  • Probably 72 hours (but if you exercise frequently, perhaps this number drops to ~36 hours)

Read the full notes @ podcastnotes.org



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There’s a lot of speculation about when autophagy starts and stops. In today’s show we’ll cover the details.

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About Today's Show:

“Fast for 18 hours and autophagy kicks-in,” the guru says.

The truth is, autophagy is occurring at different rates in different tissues for different people.

In this show, we’ll add some clarity to this topic that’ll help you figure out how long and frequently you should fast to enhance autophagy.

-Insights from human fasting studies about autophagy and fast duration
-Herbs and foods that may enhance autophagy

Link to show notes and research: https://highintensityhealth.com

Related Podcast with Peter Attia, MD: http://bit.ly/2QWLAAY

Autophagy and Time-Restricted Feeding: https://www.instagram.com/p/Bya8oWNJNpF/