In this dense and technical episode with Dr Tommy Wood, we introduce Hormetea!

Why Hormetea?

We love polyphenols - those magical compounds from plant foods that lend them their bright colours and multiple health benefits. The greens and yellows in tea, the deep orange of turmeric, and purples of berries. Many of these compounds provide some of their benefits by activating the metabolic machinery associated with fasting and autophagy - a process known as hormesis. To get all these great compounds in one place, we went into the kitchen and cooked up a tea - Hormetea. In one serving, you’ll find the best-researched plant polyphenols in doses that have been clinically-proven to reduce inflammation and improve metabolic health, with a touch of pepper to increase bioavailability. We’re sure you’re going to love it!

We will send the first 100 people that leave us a 5-star review on iTunes (video instructions) a 50g sample of Hormetea. Please send your US shipping address to [email protected]

About the Hormetea ingredients:

Polyphenols

• Seem to be synergistic (i.e. EGCG inhibits the enzymes that metabolise quercetin)
• Anthocyanins (and quercetin) from bilberry
• Improves glucose tolerance in obese patients (when given with prebiotics)
• Improves disease score in UC (including reduced calprotectin)
• Reduces oxidative DNA damage
• Improves vascular function
• Improves gait speed and agility in the elderly
• Reduce insulin and glucose responses to carbs
• Inhibits MMPs (MS)

Matcha - green tea catechins

• May help reduce fat mass (but requires synergism with caffeine, and may be better in caffeine naive)
• Improves insulin sensitivity
• Improves cognitive function in those with cognitive decline (with L-theanine)
• Reduces carbohydrate absorption (like anthocyanins)

Grape seed extract

• Improves blood pressure and inflammation and glycaemic control in IR
• Reduces oxLDL

Turmeric

• 1-5% curcumin
• Increase bioavailability with pepper
• Likely to not reach high systemic levels - use Meriva
• BUT 1-2g of turmeric can reduce CRP
• Improved working memory when given with carb load
• Rest is good for the gut
• Indigestion
• Increased intestinal ALP and reduced permeability?

Broccoli seeds

• Highest content of sulforaphane
• Activated by heat (~160F)
• Lots of epidemiological studies on cruciferous veggies and cancer and all-cause mortality (another)
• But make sure you’re iodine-replete!
• Activates Nrf2 and antioxidant defence
• BrSp extracts are neuroprotective in rats
• Improves insulin resistance in T2DM
• Improved behaviour in ASD
• Improves 8-OHdG, GGT, and ALT in those with fatty liver

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Here’s the outline of this podcast with Tommy Wood, MD, PhD:

[00:00:29] Icelandic Health Symposium. Tommy's talk from last year’s event.

[00:02:25] This year’s event is called Who Wants to Live Forever.

[00:02:41] Maryanne DeMasi was last year’s host, this year it’s Tommy!

[00:02:55] Speakers: Ben Greenfield, Dr Bryan Walsh, Diana Rogers, Dr Dominic D’Agostino, Dr Doug McGuff, Dr Rangan Chatterjee, Dr Satchidananda Panda.

[00:03:49] Speaker dinner.

[00:03:58] Practitioner workshop.

[00:04:59] Mountain biking in Iceland.

[00:05:18] PHAT FIBRE, Wood, Thomas R., and Christopher Kelly. "Insulin, glucose and beta-hydroxybutyrate responses to a medium-chain triglyceride-based sports supplement: A pilot study." Journal of Insulin Resistance 2.1 (2017): 9.

[00:06:46] PFv2 is more ketogenic (C8 oil).

[00:07:01] Some glucose is required even in low-carb athletes.

[00:07:37] Professor Kieran Clarke.

[00:09:06] Testing nutritional supplements.

[00:10:10] Professor Elizabeth Nance.

[00:10:48] Hormetea.

[00:11:14] Hormesis.

[00:11:32] Plant polyphenols.

[00:12:03] Rhonda Patrick, PhD.

[00:13:28] Anthocyanins.

[00:13:53] Root causes of MS talk.

[00:16:02] Berries at the farmer's market.

[00:16:53] Frozen berries can be found online.

[00:17:19] Matcha green tea.

[00:18:52] Grapeseed extract (not grapefruit seed extract).

[00:20:38] Turmeric.

[00:21:33] Meriva.

[00:22:33] Broccoli sprouts.

[00:24:03] Morning smoothie.

[00:24:14] NRf2.

[00:26:18] Hormesis in the metabolically deranged.

[00:27:09] 8-hydroxy-2' -deoxyguanosine (8-OHdG).

[00:28:12] Hormetea preparation instructions.

[00:29:27] Video instructions for review.

[00:31:57] Organic acids test (OAT).

[00:32:24] Podcast: Bill Shaw, PhD.

[00:33:35] Tommy's results: before and after.

[00:33:46] Qualia (we have no financial affiliation).

[00:35:21] PhD defence.

[00:36:07] Acute stimulation then a come down.

[00:38:23] MOA dopamine.

[00:40:05] Professor Robert Sapolsky dopamine video.

[00:42:05] Noradrenaline (because there ain’t no receptor for norepinephrine).

[00:43:10] Serotonin.

[00:44:28] Kyurinate and quinolinate.

[00:44:56] 5-HTP

[00:47:30] Book a free EPP Starter Session.

[00:48:43] Model of encephalopathy of prematurity at the University of Washington.

[00:53:53] Sign up for our Highlights email.