In today’s special episode you’ll hear our very own Andrés Preschel stepping behind the microphone to be interviewed by Dr. Rick Komotar for his podcast, The Crossover. Dr. Komotar is a Neurosurgeon at Columbia University Medical Center and is the Director of the Brain Tumor Initiative as well as the Brain Tumor Fellowship Program. Tuning in you’ll get to know Andrés a little better, including what motivates his passion for physiology and helping people. In their conversation, Andrés breaks down the top ten things everyone should know about their physiology, along with tips on how anyone can apply these lessons to their everyday life. Discover the importance of hydration, why the female biorhythm is infinitely more complex than their male counterparts, and what the Heart Rate Variability (HRV) biometric marker can teach us about how we manage stressful situations. Andrés also unpacks the importance of incremental change, why everyone’s physiology is unique, and how to monitor your own body. To learn more about our host, how to make positive lifestyle changes, and much more, make sure you tune in today!

Key Points From This Episode:

• Get to know your host Andrés Preschel, and his guide to physiology.
• How Andrés became interested in physiology as a specialization.
• The circumstances that prompted Andrés to start this podcast, Know Your Physio.
• Learn about Andrés’s team and the role they play in facilitating accessible science.
• Discover the team at Hambre y Hormonas, a concierge medical practice that Andrés co-founded four years ago.
• The top ten things everyone should know about their physiology.
• The female biorhythm: what it is, why women are underrepresented in medicine, and how their rhythm differs from those of men.
• Heart Rate Variability (HRV) as a biometric marker and the impact it has on how you manage stress.
• Understanding the importance of hydration.
• Why you need adequate protein in your diet and why increased muscle mass is so beneficial as you age.
• How to use applied sciences and visual stimulation to create relaxation and focus.
• The benefits of ketosis and how to achieve it without the keto diet.
• The importance of keeping your blood glucose levels as steady as possible.
• Understanding the role that hormones play in hunger and satiety levels.
• The biggest barrier to people not understanding their physiology.
• The advances in health and wellness that Andres expects to see within the coming decade.
• Andrés’s advice for anyone looking to make positive lifestyle changes.

Links Mentioned in Today’s Episode:

BiOptimizers

The Crossover Podcast

Hambre y Hormonas

Glucose Goddess

Jessie Inchauspé on Instagram

Know Your Physio Episdoe 053: Circadian Rhythms, Chronobiology, and Interoception with Azure Grant, PhD

Know Your Physio Episode 001: Fix Your Glucose, Fix Your Life with Jessie Inchauspe, the Glucose Goddess

Andrés Preschel on Instagram

Andrés Preschel

Know Your Physio Podcast

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When it comes to nutritional science and social media it can be uniquely challenging to differentiate fact from hype. Here today, to help us unpack the topic of scientific influencers and misinformation is Kevin Bass, an MD and Ph.D. student, and founder of The Diet Wars, a site dedicated to upholding evidence-based nutritional research and exposing figures who spread nutritional and scientific misinformation online. We dig into how social media can incentivize the spread of misinformation, why these systems need to change, and take a closer look at the growing community of evidence-based nutritional science experts and influencers online. Tuning in, you’ll learn how to identify legitimate scientific influencers, and what red flags you should look out for when trying to avoid misinformation. Kevin also breaks down key areas of misinformation including how to combat sun damage, the so-called harms of seed oils, and how saunas can realistically benefit your health. Combating misinformation online is a huge challenge, but we can all find ways to better navigate the online space by thinking critically and by asking the right questions. Tune in for this important conversation on nutritional science, social media, and much more!

Key Points From This Episode:

• Learn about the power of Magnesium Breakthrough by BioOptimizers.
• Introducing today’s guest, Kevin Bass.
• Kevin’s early encounters with medicine, misdiagnoses, and how it informs his perspective.
• How current systems incentivize misinformation in the nutrition space.
• The growing evidence-based community in nutritional science and on social media.
• What sets evidence-based nutritionists apart from their counterparts.
• Tips on how to discern which experts to follow online.
• The benefits and harms of sunscreen use, and suggested alternatives for sun protection.
• Some of the advantages of early morning sun exposure.
• An overview of general attitudes toward seed oils and what is based on fact versus emotion.
• The role of anti-nutrients in certain foods and how they can work synergistically with other elements to produce positive outcomes.
• Examples of how influencers misrepresent information to sell their products on social media.
• What regular blood work can teach you about your physiology and your risk factors.
• How using steroids as a health professional affects your credibility.
• An overview of saunas, their potential benefits and harms, and how to utilize them appropriately.
• The science behind cold exposure, weight loss, and building resilience.

Links Mentioned in Today’s Episode:

BiOptimizers

The Diet Wars

Kevin Bass on Twitter

Public Health Initiative Against Misinformation

Magnesium Breakthrough

Red Pen Reviews

Layne Norton

Peter Attia

Dr. Mark Hyman

Rhonda Patrick

The Peter Attia Drive Podcast

Andrés Preschel

Know Your Physio Podcast

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Today’s guest, Wade Lightheart; author, athlete, nutritionist, and expert on fixing digestion. Wade is a three-time Canadian bodybuilding champion, who competed as a vegetarian. He is one of the world’s foremost authorities on natural nutrition and training methods. After competing in Mr. Universe, and his health failed him, Wade began to search for answers and developed what he calls his Awesome Health System. Today’s podcast keys in on magnesium, which Dr. Mark Sircus identifies as the most powerful solution we have to a plethora of health problems. During our conversation, Wade gives us the full background on why 75 percent of Americans are not getting enough magnesium today and what the implications are on our health and overall wellbeing. Using the example of Tom Brady to illustrate his point, he explains how practicing bio-optimizing principles can extend the quality and length of our lives. You’ll hear about the key role that magnesium plays in supporting all areas of our health and he introduces us to the seven varieties of magnesium included in the newly optimized Magnesium Breakthrough product. Join us to hear all this and more today.

Key Points From This Episode:

• BioOptimizers’ new and improved formula for Magnesium Breakthrough.
• A discount code to get 10 percent off Magnesium Breakthrough and free shipping: ANDRES
• An introduction to today’s guest, author, athlete, and digestion expert Wade Lightheart.
• Wade’s definition for optimized health which he refers to as Awesome Health.
• The history of how our food lost magnesium content through mass production following World War 2.
• Tom Brady’s story of extending his career by 25 percent by practicing bio-optimizing principles.
• The excessive stimulatory effect that technology has on our nervous system.
• What he attributes the lack of knowledge around the power of magnesium to: we live in an attention age, rather than an information age.
• How magnesium plays a critical role in supporting dysregulated mood and depression.
• The process of testing that Wade and his business partner did on different types of magnesium.
• What the ‘ate’ suffix refers to in magnesium varieties: how it has been molecularly bonded.
• The seven magnesium varieties in Magnesium Breakthrough: chelate, citrate, bisglycinate, malate, taurine, sucrosomial, and orotate.
• Aesthetics, performance, and health; the three areas of focus that they have.
• Elements that improve delivery: hemic and fulvic acid, B6, and manganese.
• The challenge of working with so many different-sized molecules. 
• Wade’s biohacking experiment with intravenous magnesium and what he experienced.
• How through independent and guided experimentation, he came to today’s formula.
• His bucket theory on health and nutrients illustrating the goal of being in excess.
• Why there is no threonate in Magnesium Breakthrough: patent limitations.
• The relevance of the prebiotic, probiotic, and vitamins that you take.
• An invitation to spread the word if you use the products and love them.

Links Mentioned in Today’s Episode:

BiOptimizers
Cognibiotics
Wade Lightheart on Instagram

Awesome Health Podcast
Dr Mark Sircus

Andrés Preschel

Know Your Physio Podcast

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Your health is not only of significance and importance to just you. Self-care is not selfish, self-care is the new healthcare and it’s vital in life and in our communities. Today’s guest is Leigh Erin Connealy, M.D., who is a prominent leader in the field of Integrative and Functional Medical. She utilizes the best of all sciences including homeopathic, conventional, Eastern medicine, and modern medicine and is the Medical Director of two unique clinics: The Center for New Medicine and Cancer Center for Healing. The Center For New Medicine focuses on prevention and internal medicine, early detection of disease and cancer, human optimization, yearly physicals, auto-immune disease, natural hormone replacement, chronic issues, and aesthetics. Dr. Connealy feels we must treat “the whole person”, the patient with the disease and not the disease of the patient, while determining the origin of the illness. Dr. Connealy created the Cancer Center for Healing because of the epidemic spread of cancer. Patients receive scientifically based treatments and integrative protocols. She has created an acute awareness of the need to focus on cancer prevention, providing unique testing to determine the early stages of cancer, years before it is revealed in a scan. This is a fascinating conversation with a physician that firmly believes in taking in the entire picture and empowering and educating her patients, while advocating for patients to get treated with the most up-to-date medicine. As listeners tune in they’ll hear from Dr. Connealy about how she got to where she finds herself today and how everything in the way we live life integrates into our health, as she likes to say, “Self-care is healthcare”. So tune in today, and enjoy! 

Key Points From This Episode:

• We start with Dr. Connealy’s “Why.”
• She shares a thorough background of her life and what lead her to where she is now.
• How her health detours have dramatically changed her life and influenced her career.
• She shares thoughts about how disease diagnosis has changed over the last 65 years.
• The importance of health practitioners using updated medicine. 
• Treating the whole person; their lifestyle and how they’re living is important in treatment!
• Why self-care is the new healthcare.
• Why empowering and educating patients to do scientific self-discovery is a key part of her practice.
• First-symptom effect: what it’s like taking a patient through this.
• Why patients should not take “no” for an answer when seeing a physician. 
• Energy imbalances: the scenarios that lead to the crash. 
• The future of medicine: energy medicine.
• Why every patient is their own clinical trial. 
• Recommendations for water filtration devices/brands from Dr. Connealy.
• We end the conversation with a few rapid-fire questions: sea oils and sunscreen. 

Links Mentioned in Today’s Episode:

BiOptimizers

Leigh Erin Connealy on LinkedIn 

Leigh Erin Connealy on Twitter

Leigh Erin Connealy on Instagram

Leigh Erin Connealy on FaceBook

Leigh Erin Connealy on TikTok

Magnesium Breakthrough

Andrés Preschel

Know Your Physio Podcast

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It’s incredible how you can have a conversation with someone that’s almost 2 hours long, and still feel like you could keep talking! Joel Greene is the CEO of VEEP Nutrition, author of The Immunity Code, and one of the original proponents for prioritizing the gut microbiome (to mention just a few of his many accolades). Joel grew up in the projects, raised by a single mom and surrounded by violence. His upbringing made him resilient, fearless, and determined to learn as much as he could about as much as he could! Our conversation is part philosophical and part scientific and some of the many topics that we cover today include how you can train your insulin sensitivity (and why you should), why you should set aside time for stillness every day, and what you can do to keep your muscles young. This episode is filled with powerful insights from start to finish and you’ll walk away with a whole new appreciation for your gut microbiome and a whole lot of knowledge about how to live better and age better!

Key Points From This Episode:

• Introducing today’s guest, Joel Greene!
• An overview of the 16 Personalities personality test, and the value of understanding your personality type.
• The harsh challenges that Joel experienced growing up, and how they have shaped him into the person he is today.
• The role that God plays in Joel’s life.
• Why Joel prioritizes rest and stillness.
• Joel explains the correlation between physical health and productivity.
• Nicotinamide mononucleotide; why Joel takes this supplement first thing in the morning.
• Joel explains how his Immunity Code diet works, and the benefits of it.
• Insulin sensitivity; what it is and the importance of training it. 
• Joel’s approach to bringing down his cortisol levels.
• The value of pre-load meals. 
• A new way to think about carbohydrates.
• How the bacteria in your gut affect your reactions to certain foods.
• Commonalities versus bio-individualities; Joel’s thoughts on the problem of emphasizing the latter.
• Understanding the gut microbiome.
• Factors that indicate how your gut microbiome is functioning.
• Reasons for my imminent move to Uruguay.
• Supplements that are helpful for managing stress.
• Muscles that we lose as we age, and how to slow down the aging process.
• Exploring the first law of thermodynamics in relation to calories.

Links Mentioned in Today’s Episode:

BiOptimizers

Joel Greene on Instagram

Joel Greene on LinkedIn

VEEP Nutrition

The Immunity Code

Andrés Preschel

Enneagram Test

16 Personalities

Know Your Physio Podcast

Support the show

Today, we are joined by well-versed physiologist, Azure Grant, Ph.D. to talk about all things circadian and ultradian rhythms, melatonin, sleep optimization, hormones, and more! Azure has a specialization in chronobiology and studies the connections between metabolism, reproduction, and the autonomic nervous system (ANS). In this episode, we touch on everything from the science behind the siesta ‘slump’ and the effect of caffeine on our sleep cycles, to the importance of reducing the causes of fatigue, not just the sensation of fatigue. Azure explains circadian and ultradian rhythms and fills us in on the health benefits of optimizing our natural oscillations. We discover what it might feel like to live according to our chronotype, and how biometrics play a role in interoception awareness. We also find out the long-term effects of melatonin supplements, how best to naturally optimize sleep, how women’s hormonal changes affect thermoregulation, and so much more! Tune in to find out more about how our biological rhythms work, and about the natural ebbs and flows that are essential to optimal health!

Key Points From This Episode:

• Introducing our esteemed guest and chronobiology specialist, Azure Grant, Ph.D.
• Understanding the siesta ‘slump’: causes and remedies.
• What circadian and ultradian rhythms are, respectively.
• How caffeine later in the day often perpetuates sleep difficulties.
• The importance of reducing reasons for fatigue, not just the sensation of fatigue.
• The early observations that inspired Azure’s health quest.
• The oscillating nature of the body’s functions and the health benefits of optimizing our natural biological rhythms.
• How it feels to live according to your chronotype.
• Why it’s important to establish your optimal circadian rhythm and what that involves.
• Biometrics as a key component of interoception awareness.
• How to balance your circadian rhythm in the wake of jetlag: intermittent fasting and focusing on ultradian rhythms.
• The value of ultradian stability.
• Why large meals aren’t recommended at the end of the day.
• Downsides of disrupting sleep cycles.
• The link between thermoregulation and hormonal changes.
• The role of naturally occurring melatonin and the long-term effects of supplementation.
• Azure’s non-negotiables for sleep!
• The benefits of morning light.
• Azure answers our rapid-fire questions about REM cycles, sleep aid, and sleep disruptors.  

Links Mentioned in Today’s Episode:

BiOptimizers

Azure Grant, PhD

Azure Grant on LinkedIn

Azure Grant on Instagram

Azure Grant on Twitter

Levels

Crescent Health

Andrés Preschel

Andrés Preschel on Instagram

Email Andrés Preschel

Know Your Physio Podcast

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One of the major benefits of a functional approach to health and wellness is that it allows us to treat systemic issues from the root cause, rather than with interventions that have side effects. Talking to us today about how she became a functional nutritionist, and why she is so passionate about the field, is Cata Rozo. From her personal battles with gut health and how it impacted her hormones and liver, Cata describes her journey, and why it's her mission to help others. We learn about the link between gut health and hormones, and whether you should be considering a functional approach or a conventional approach to your health. Tune in to hear about the types of tests Cata uses to assess her patients, and the techniques she uses to improve interoception. We find out why Cata is so passionate about empowering women to find alternatives to the oral contraceptive as a therapy, and what you can do to improve your perceptions of your health. Andrés describes how he learned the importance of eating when in a parasympathetic state, while Cata explains how food sensitivities are developed, and how exclusion and reintroduction diets work. For all this, and so much more, press “Play” now!

Key Points From This Episode:

• Welcome to functional nutritionist Cata Rozo, and why she does what she does. 
• Why Cata supports getting a second opinion, and doing your own research. 
• When to choose functional medicine over conventional medicine. 
• A reminder that feeling good is how we are meant to feel!
• How unlocking physical health contributes to emotional wellbeing. 
• The relationship between gut health and hormones. 
• How Cata assesses her client’s gut health, and why being able to digest food is more important than what we eat. 
• The decision-making fatigue Andrés sees in health and wellness. 
• Cata’s specific area of interest: empowering young women to make their own decisions when considering the oral contraceptive as a treatment for health conditions. 
• Cata’s tips on improving your interoception: meditation, yoga, and writing. 
• The idea of using yoga as a preventative approach to chronic conditions. 
• Addressing your thoughts on your physical state: connecting your thoughts to your health. 
• The tests Cata recommends to get to know your physical health. 
• Balancing food sensitivities with required dietary nutrients. 
• Why we develop food sensitivities.
• Why Cata prefers lab-based food sensitivity tests over home kits. 
• How to best prepare for a food sensitivity test!
• Why we should only be eating when in a parasympathetic state.
• Andrés’ experience of praying before eating and how it helped him appreciate the power of the parasympathetic state. 
• The science that Cata is most excited about right now: eating more fermented food, watching the order you eat different food groups in, and organ meats and bone broth. 
• Why you can eat too much fermented food, and how to prepare your body for it. 
• A wrap of today’s episode and why Cata is so excited about the holistic approach to functional nutrition. 
• When Cata’s knowledge works against her!

Links Mentioned in Today’s Episode:

BiOptimizers

Cata Rozo on Instagram

Viome

Andrés Preschel

Know Your Physio Podcast

Support the show

A common myth about heart rate variability (HRV) is that the greater it is, the healthier you are… Breaking down why this is not the case, is Dr. Jay Wiles, an expert in applied psychophysiology and heart rate variability, and founder of Hanu Health. We start the episode with a discussion around how Jay and Andrés have become more comfortable over time with podcasting, and why they track their HRV and HR to gain insight into how different experiences affect their health. Tune in to learn what the Hawthorne effect is, how to overcome it, and why you should trust your body over the information provided by biometric data readers. We also find out what interoception is, how Jay uses it as a party trick, and where Andrés feels he is most in tune with it! Jay reveals some exciting prospects regarding the launch of the Hanu wearables, where (and why) you should pre-order one, and what you will gain when you join the Hanu Health community. For a breakdown of the physiology underlying HRV, the links between muscle tension, HRV and respiratory sinus arrhythmia, and so much more, join us today! 

Key Points From This Episode:

• How Andrés and Jay have become more comfortable during podcasts and tracking HR and HRV through different behaviors.
• What the Hawthorne effect is, and how Jay coaches people through it. 
• When you should listen to the biometric data, and when you should listen to your body. 
• How to approach interoception, what it is, and why Jay founded Hanu Health. 
• Andrés' extreme example of interoception when freediving and spearfishing. 
• How you can find out your normative HRV range, and the common myths around HRV. 
• The classic symptoms of high HRV. 
• Some of the differences between men and women in muscle tension, and how this impacts HRV. 
• The link between emotional distress and muscular tension. 
• Jay’s theory on how ketones might increase HRV.
• Respiratory sinus arrhythmia: what it is, and how it influences HRV.
• The products Jay and Andrés use to help their mental acuity from nicotine to KE4. 
• How long it will take you to establish your HRV baseline. 
• When to wear your Hanu device, and what makes it unique as a wearable. 
• What to expect from the launch of Hanu wearables, and why it’s such a bargain to pre-order!
• How long you should use the Hanu device before your interoception reaches a level that renders the device non-essential. 
• The library of data you will gain access to when you join Hanu. 
• Bringing the metaverse into health and biohacking.

Links Mentioned in Today’s Episode:

BiOptimizers

Dr. Jay Wiles on LinkedIn

Dr. Jay Wiles

Dr. Jay Wiles on Facebook

Dr. Jay Wiles on Instagram

Hanu Health

Hanu Health on Twitter

Hanu Health on Facebook

Hanu Health on Instagram

Lucy

The Fuel Stop: Methylene Blue

Marco Altini

Andrés Preschel

Know Your Physio Podcast

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To celebrate the 50th episode of the Know Your Physio podcast, Andrés Preschel takes the hot seat! His amazing partner, Parker Sloan Leiro, AKA “The Rolling Sloan” takes over to ask all the pressing questions. We hear all about KYP’s goal to make science sexy and accessible, and the immense value that Andrés has gained from hosting the podcast. In this episode, we find out which episodes impacted Andrés most profoundly and the amount of work that goes in, behind the scenes. Andrés touches on topics of fear setting, slow productivity, and what drives motivation, sharing astute advice for those seeking success in a saturated field. Tune in to find out where the goal to improve listeners’ overall health literacy is leading Andrés in his personal and professional life, as he shares his infectious passion for scientific self-discovery.

Key Points From This Episode:

• The benefits of BiOptimization’s new Magnesium Breakthrough supplement.
• What inspired Andrés to start the podcast!
• The unexpected growth and success of the podcast.
• Andrés recounts the KYP episode with early podcast guest, Romero Britto.
• What he admires most about Romero Britto.
• Which guests and episodes have affected Andrés’ life most profoundly.
• What he has learned through hosting the podcast.
• Andrés breaks down the work and intentions of the KYP brand and company.
• The work Andrés puts in behind the scenes.
• What drives motivation.
• What fear setting is and why Andrés pursues discomfort.
• Parkinson’s disease simply explained.
• How Andrés has remained present through the exponential growth of his personal brand.
• The importance of pacing yourself as you work towards long-term goals.
• Andrés’ advice for those seeking success in a saturated field.
• The concept of slow productivity. 
• Andrés’ favorite episodes so far and what’s in store for the future!
• The immense value Andrés has gained from podcasting.
• Why Andrés and Parker are moving!
• Stay tuned for the KYP newsletter.

Links Mentioned in Today’s Episode:

BiOptimizers

Parker Sloan Leiro on Instagram

Romero Britto

Dr. Morgan Levine on Instagram

Frank Llosa on LinkedIn

KetoneAid

Cal Newport on Slow Productivity

The Huberman Lab Podcast: The Science of Setting & Achieving Goals

Know Your Physio Episode 016: Patrick Porter

Anthony Benedettini

Andrés Preschel

Know Your Physio Podcast

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Today on Know Your Physio we are talking about the revolutionary stress management tool, Apollo, with one of its creators, Dr. David Rabin. Our guest is a board-certified psychiatrist and neuroscientist who specializes in the treatment of chronic stress, and he is here to tell us all about the groundbreaking device providing a safe, non-invasive way to manage stress on the spot and assist us on our paths to self-actualization! We find out how it works to elicit calm by using soundwaves felt through the skin, and Dr. Rabin explains why touch therapy is so effective. We discover the profound benefits of using the Apollo device, how it affects one’s HRV and decision-making ability, optimizes health, and its use in treating PTSD sufferers. Tune in to hear more about this impactful invention that’s putting people in control of their own healing, confidence, and safety!

Key Points From This Episode:

• How Andrés’ Apollo device has benefited him.
• Dr. David Rabin’s public speaking journey and how Apollo has aided him.
• How touch therapy can improve one’s ability to achieve a relaxed state.
• The intention behind the invention of Apollo.
• Why touch therapy is so effective.
• What the Apollo looks like, how it’s worn, and what it does.
• The versatility of the device and the various physiological states it can elicit.
• André’s findings from his personal experiment with Apollo.
• How Apollo was created and came to be a consumer product.
• What HRV is and how it’s affected by stress.
• How measuring HRV allows for health optimization.
• Reframing health and self-actualization.
• How our decision-making ability is affected by a real or perceived threat.
• How the profound intention and impact of the creation of Apollo have affected Dr. Rabin’s life.
• How to gauge your ability to manage stress according to the effectiveness of the Apollo.
• How soothing touch affects the brain from a physiological perspective.
• The effects of the Apollo on people with acute stress, illness, or PTSD.
• How Dr. Rabin’s research in the realm of psychedelics impacted the creation of the Apollo.
• How the Apollo can be used to assist psychedelic experiences in therapy.

Links Mentioned in Today’s Episode:

BiOptimizers

Dr. David Rabin

Dr. David Rabin on LinkedIn

Dr. David Rabin on Instagram

Apollo Neuroscience

Andrés Preschel

Know Your Physio Podcast

Support the show