Leslie Kenny reversed her autoimmune diseases and rejuvenated her biological age, literally saving herself from a 5 year prognosis in her thirties. Here, she discusses her process and the 12 hallmarks of ageing, she shares her experience with rheumatoid arthritis and lupus, her decision to take control of her health, and the treatments that led to her remission.

Leslie also talks about her experience with perimenopause and menopause and the importance of managing cortisol and progesterone levels. She introduces the 12 hallmarks of ageing, including stem cell dysfunction, mitochondrial dysfunction, inflammation, impaired autophagy, and more.

She highlights the role of spermidine in rejuvenating senescent immune cells. Spermidine, a compound found in plants and semen, has the ability to inhibit nine out of 12 hallmarks of ageing. It is crucial for the survival and growth of the next generation, present in breast milk and semen. As we age, our ability to produce spermidine decreases, making it important to obtain it from our diet. Lifestyle choices, such as a diet rich in prebiotic fibre from plants, can increase the production of spermidine in our bodies. Spermidine supplementation has been shown to promote hair growth, improve sleep, enhance heart health, and activate autophagy, a process that removes dysfunctional cells and mitochondria.

You can find Leslie at https://oxfordhealthspan.com/ and use code HATTY15 for a 15% discount on Primeadine.

Feel free to reach out and drop me a line with any questions, comments or feedback as I always love to hear from you: [email protected]

00:00Introduction and Background 02:18Diagnosis and Taking Control of Health 06:24Navigating Perimenopause and Menopause 08:07Understanding the 12 Hallmarks of Aging 21:26The Importance of Spermidine in Reproduction and Gut Health 23:12The Role of Diet and Lifestyle in Spermidine Production 35:57Activating Autophagy with Spermidine