Dr. David Sabatini is an American scientist and Professor of Biology at  the Massachusetts Institute of Technology as well as a member of the  Whitehead Institute for Biomedical Research. He is known for his  important contributions in the areas of cell signaling and cancer  metabolism, most notably the discovery of mTOR, more than 20 years ago.  Since then Dr. Sabatini has continued to work on better understanding  this complex regulator of our metabolism In this video Dr. Sabatini discusses how mTOR impacts lifespan and  whether its actions change with age  

Some key references. 

Twenty-five years of mTOR: Uncovering the link from nutrients to growth https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692607/  

mTOR introduction YouTube Series with Dr. Sabatini https://www.youtube.com/watch?v=EnIerDljc7g https://www.youtube.com/watch?v=defOfBEuw_M https://www.youtube.com/watch?v=tGA9RALG66s