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What happens if the thyroid medication that finally helped you feel like yourself becomes harder to access?
Natural desiccated thyroid has been used for decades, and many women prefer it because it provides both T4 and active T3. Proposed FDA changes have raised questions about its future, but they also bring a much bigger issue into focus.
Why do so many women still struggle with fatigue, brain fog, weight changes, cold intolerance, and low energy even when they are taking thyroid medication and their lab results are considered "normal"?
Pharmacist and compounding expert Nat Jones explains what more complete thyroid care can look like for women in perimenopause and menopause. We explore why T4 alone may not be enough for every woman, how stress and cortisol can interfere with thyroid function, and how compounded T4/T3 therapy can offer a more individualized approach.
What You'll Discover In This Episode
Why some patients prefer natural desiccated thyroid to levothyroxine
T4 vs. T3: why having both can make a meaningful difference
What your options are if desiccated thyroid becomes harder to access
Why women still feel hypothyroid when their TSH is "normal"
How compounded T4 and T3 can be customized to the individual patient
Why standard thyroid ratios do not work equally well for everyone
The overlooked role of cortisol and chronic stress in thyroid treatment
The additional thyroid markers that may reveal what TSH misses
How ferritin and nutrient deficiencies can affect thyroid function
Why Hashimoto's requires more than simply replacing thyroid hormone
PS. If you enjoy the show, remember to leave a review on your favorite podcast app! Reviews help the podcast reach a wider audience and help more people.
About the Guest
Nat Jones is a pharmacist and internationally recognized expert in pharmaceutical compounding. After more than 20 years as a compounding pharmacy owner, he joined Professional Compounding Centers of America (PCCA) in Houston, Texas, in 2014, where he serves in the Pharmacy Clinical Services Department.
Dermatology is Nat's primary specialty, with additional expertise in wound and scar care, autoimmune disease, endocrinology, pain management, low-dose naltrexone, GLP-1 therapies, methylene blue, ENT, urology, and men's health. He has spent decades delivering continuing education lectures at medical seminars and webinars around the world and is known for translating complex compounding science into practical strategies healthcare providers can use.
Nat was awarded Fellowship status by the International Academy of Compounding Pharmacists in 2010. He has authored numerous professional articles, e-books, case studies, and consumer publications, and has helped develop hundreds of innovative compounding formulations used by practitioners across the United States.
About Your Host
Steve Hoffart is an award-winning pharmacist, entrepreneur, speaker and podcaster. As the visionary founder of Magnolia Pharmacy, Steve saw a need for a more personal pharmacy that could make a bigger impact. Today, Steve and his team of experts deliver on that promise, working with patients and their physicians to solve medication problems and offer personalized solutions to achieve better health and wellness. As host of The Trusted Pharmacist podcast and through his combined reach of over 1M on social media, Steve shares actionable advice on nutrition, supplements, and wellness strategies while advocating for meaningful change in healthcare.
Stay Ahead with Steve the Pharmacist!
Loving the show? Want more insights into how your body works? Head over to TheTrustedPharmacist.com and sign up with your email! You'll get the latest episodes, plus exclusive health tips to help you take charge of your wellness. Don't miss out – join me today!
By Steve Hoffart4.9
3030 ratings
What happens if the thyroid medication that finally helped you feel like yourself becomes harder to access?
Natural desiccated thyroid has been used for decades, and many women prefer it because it provides both T4 and active T3. Proposed FDA changes have raised questions about its future, but they also bring a much bigger issue into focus.
Why do so many women still struggle with fatigue, brain fog, weight changes, cold intolerance, and low energy even when they are taking thyroid medication and their lab results are considered "normal"?
Pharmacist and compounding expert Nat Jones explains what more complete thyroid care can look like for women in perimenopause and menopause. We explore why T4 alone may not be enough for every woman, how stress and cortisol can interfere with thyroid function, and how compounded T4/T3 therapy can offer a more individualized approach.
What You'll Discover In This Episode
Why some patients prefer natural desiccated thyroid to levothyroxine
T4 vs. T3: why having both can make a meaningful difference
What your options are if desiccated thyroid becomes harder to access
Why women still feel hypothyroid when their TSH is "normal"
How compounded T4 and T3 can be customized to the individual patient
Why standard thyroid ratios do not work equally well for everyone
The overlooked role of cortisol and chronic stress in thyroid treatment
The additional thyroid markers that may reveal what TSH misses
How ferritin and nutrient deficiencies can affect thyroid function
Why Hashimoto's requires more than simply replacing thyroid hormone
PS. If you enjoy the show, remember to leave a review on your favorite podcast app! Reviews help the podcast reach a wider audience and help more people.
About the Guest
Nat Jones is a pharmacist and internationally recognized expert in pharmaceutical compounding. After more than 20 years as a compounding pharmacy owner, he joined Professional Compounding Centers of America (PCCA) in Houston, Texas, in 2014, where he serves in the Pharmacy Clinical Services Department.
Dermatology is Nat's primary specialty, with additional expertise in wound and scar care, autoimmune disease, endocrinology, pain management, low-dose naltrexone, GLP-1 therapies, methylene blue, ENT, urology, and men's health. He has spent decades delivering continuing education lectures at medical seminars and webinars around the world and is known for translating complex compounding science into practical strategies healthcare providers can use.
Nat was awarded Fellowship status by the International Academy of Compounding Pharmacists in 2010. He has authored numerous professional articles, e-books, case studies, and consumer publications, and has helped develop hundreds of innovative compounding formulations used by practitioners across the United States.
About Your Host
Steve Hoffart is an award-winning pharmacist, entrepreneur, speaker and podcaster. As the visionary founder of Magnolia Pharmacy, Steve saw a need for a more personal pharmacy that could make a bigger impact. Today, Steve and his team of experts deliver on that promise, working with patients and their physicians to solve medication problems and offer personalized solutions to achieve better health and wellness. As host of The Trusted Pharmacist podcast and through his combined reach of over 1M on social media, Steve shares actionable advice on nutrition, supplements, and wellness strategies while advocating for meaningful change in healthcare.
Stay Ahead with Steve the Pharmacist!
Loving the show? Want more insights into how your body works? Head over to TheTrustedPharmacist.com and sign up with your email! You'll get the latest episodes, plus exclusive health tips to help you take charge of your wellness. Don't miss out – join me today!

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