Peptide of The Week

Peptide of The Week

By JD Denham and Will Haas

Hosted by JD Denham and Will Haas, The Peptide of The Week Podcastis your no-BS guide to peptides, performance, and total body optimization. Whether you’re an athlete, a high performer, or just hungry... more
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  1. Number 1: Peptide of the Week: GHK-Cu, Glow & Klow – The Ultimate Healing & Skin Stack

    Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk. Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas break down GHK-Cu, the Glow stack, and the Klow stack what they are, how they work, how to use them properly, and why they belong in almost everyone's protocol. Chapters: 00:00 – Summer Plans, Travel & Prague Lab Visit 05:00 – Why Vacations Matter & Working Smarter 09:59 – Touring Janoshik Labs & Quality Testing 12:32 – GHK-Cu, Glow & Klow Explained 19:48 – How to Use GHK-Cu Face Serum Correctly 22:55 – GHK-Cu Shampoo & Hair Growth Benefits 29:04 – Why RETA Pairs Well with GHK-Cu 32:13 – Buffered Reconstitution & Reducing Injection Sting 33:51 – Glow vs. Klow vs. Wolverine Stack 46:09 – GHK-Cu Dosing, Cycling & Copper Safety 49:55 – Tattoos, Healing & Final Takeaways We cover: 🧬 What is GHK-Cu? – Copper peptide its primary job is signaling your body to produce more natural collagen – Reduces and corrects skin inflammation – Helps with wound healing, skin elasticity, fine lines, wrinkles, dark spots, and hair thinning – GHK-Cu levels decline from ~200 ng/mL at age 20 to ~80 ng/mL at age 60 that decline shows up on your face – Sub-Q injecting GHK-Cu has been shown to darken hair pigmentation — biochemically based, not hearsay – GHK-Cu vs Minoxidil: GHK-Cu was found favorable in trials for hair growth – A wound healing double-blind clinical trial on topical GHK-Cu serum is scheduled for 2026 💉 How to use the Face Serum correctly – Use a dermal roller first opens the skin so it absorbs properly – Clean the roller in alcohol before use – Apply serum after rolling 3 days per week is the sweet spot – Works if you just apply it, but works significantly better with the roller – JD and his wife cut laser facial healing time in half using it friend who skipped the serum healed much slower – Do NOT use numbing cream with the dermal roller Will learned this the hard way 🧴 GHK-Cu Shampoo – Leave it in for 1.5–2 minutes before rinsing longer contact = better results – Prolongs the hair follicle growth phase and stimulates thicker follicle growth – Won't regrow hair on a completely bald scalp, but does make a noticeable difference – A hairdresser in Orange County was blown away by results on her own thinning hair now sells it in her salon 🌟 Glow Stack (GHK-Cu + BPC-157 + TB-500) – GHK-Cu: collagen production, skin repair, wound healing – BPC-157: signaling peptide finds injuries, reduces inflammation, converts food into collagen building materials. Origin story: the peptide that prevents stomach acid from burning through your stomach lining – TB-500 (Thymosin Beta-4): recruits stem cells, sends them where BPC-157 directs, reduces inflammation, accelerates tissue repair – Together: BPC finds the problem, TB-500 sends the workforce, GHK-Cu builds the collagen 💪 Klow Stack (GHK-Cu + BPC-157 + TB-500 + KPV) – Everything in Glow PLUS KPV for gut health – KPV calms gut inflammation, helps leaky gut, modulates immune response – Most autoimmune issues start in the gut KPV addresses the root – Best all-in-one health and healing stack available 📺 Subscribe for more no-fluff peptide education every week. Follow us on social media: JD's Instagram: https://www.instagram.com/jddenhamofficial/ Will's Instagram: https://www.instagram.com/williamthaas/ Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/ Join The Community: https://www.skool.com/peptideoftheweekcommunity

    55min
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  2. Number 2: Peptide Q&A #51 – HGH vs IGF-1 LR3, Wolverine for Dogs, GHRH & GHRP Explained & Low Libido on TRT

    Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk. Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover whether HGH and IGF-1 LR3 can be stacked safely, why libido stays low even on TRT, Wolverine protocols for a 69-year-old with nine surgeries, why peptides don't show on drug tests, and how to dose BPC and TB-500 for a 125-pound dog. Chapters 00:00 – Intro 00:09 – Newport Dunes, Family Trip & Prague Plans 03:24 – The Future of Peptide Testing & COAs 09:32 – HGH vs. IGF-1: Should You Stack Them? 18:56 – Wolverine Stack for Surgery & Injury Recovery 22:00 – Healing the Gut with BPC-157 & KPV 26:45 – RETA, Weight Loss & High LDL Explained 30:27 – Why GHRHs & GHRPs Work Better Together 34:07 – Low Libido on TRT: What You're Missing 42:13 – Do Peptides Show Up on Drug Tests? 44:39 – RETA, Muscle Gain & Increasing Your Metabolism 50:58 – Ulcerative Colitis, Wegovy & Switching to RETA 53:16 – Using Peptides for Dogs & Surgery Recovery 55:56 – Peptides Before Surgery, Fasting Protocol & Community Updates We cover: • HGH + IGF-1 LR3 Together Safe or Not?: Why doubling up amplifies muscle building but also amplifies insulin sensitivity risk and who should and shouldn't do it • Why GHRH and GHRP Work Better Together: How Sermorelin and Ipamorelin amplify each other's pulses and why Tesamorelin plus low-dose Ipa is the best combo for women prone to water retention • 69-Year-Old LEO with Nine Surgeries: Why high-dose Wolverine is safe, why two migs of each daily post-surgery is the target, and why injecting close to the site matters • Diverticulosis & Ulcerative Colitis Protocol: Why oral BPC and KPV are the foundation and why most medications are probably making the gut worse • High LDL on Retatrutide in Women: Why rapid fat loss temporarily raises LDL, why it's not alarming at 106, and why the scale is the wrong metric to chase • Low Libido at 44 on TRT: Why free testosterone matters more than total, why 100 migs may be too low, and why diet, sleep, cortisol and estrogen all outrank more testosterone • Do Peptides Show Up on Drug Tests: Why no standard employment test screens for peptides and why the economics of testing make it nearly impossible • Gastric Sleeve Patient Stalled at 145 Pounds: Why eating more protein not fewer calories is the fix and why adding Tesamorelin and Ipamorelin raises your BMR over time • Switching Mom from Wegovy to Retatrutide: Why going pound for pound on dosage is the simplest approach and why she'll feel hunger again and that's okay • Wolverine Protocol for a Saint Bernard Post Spinal Surgery: Why a human-sized dose is appropriate for a 125-pound dog, what the beagle studies show, and how to inject intramuscular You're a warrior. Act like one. Follow us on social media: JD's Instagram: https://www.instagram.com/jddenhamofficial/ Will's Instagram: https://www.instagram.com/williamthaas/ Join The Community: https://www.skool.com/peptideresearchinstitute/about Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

    59min
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  3. Number 3: Peptide of the Week: Blood Work, Gut Health & Gear – With Dr. Scott Collie

    Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk. Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas sit down with their personal functional medicine doctor and longtime friend, Dr. Scott Collie, for a deep dive into blood work, cardiovascular health, gut health, thyroid, and what actually matters when you are running gear or peptides. Chapters: 00:00 – Intro: Dr. Scott & Talking Real Food (Italy Recap) 05:29 – The Truth About "Running Gear" 06:15 – TRT vs. Steroid Cycles Explained 10:22 – Why Bloodwork Timing Matters On vs. Off Cycle 12:58 – Blood Sugar, Insulin & GLP-1s 17:45 – Kidney, Liver & Iron Health Markers 22:25 – Understanding Cholesterol: LDL, HDL & VLDL 27:31 – Thyroid Health & Hashimoto's 30:06 – Homocysteine & Methylation 35:13 – Rapid Weight Loss & Gallbladder Risks 39:16 – Inflammatory Markers & Heart Damage Warning Signs 46:02 – Top Supplements & Peptides for Cycle Support 53:41 – Cycle Timing & When to Test Blood 1:01:51 – Hydration & Final Thoughts 1:06:07 – Outro & Where to Find Dr. Scott We cover: 🩺What functional medicine actually looks at – Standard doctor panels are a snapshot, not a full picture – Dr. Scott runs up to 75 markers including cardiovascular, inflammatory, kidney, thyroid, and gut markers – Most insurance doctors stop at LDL and HDL, missing the full story completely – You need particle size, not just cholesterol weight, to understand your true cardiovascular risk 🫀 Cardiovascular markers that matter – APOB: umbrella marker for all arteriosclerotic particles including VLDL, LDL, and IDL – Particle size is critical: anabolic steroids shift particles to small dense LDL, the type that sticks and clogs arteries – Myeloperoxidase and LP-PLA2: direct markers of vascular inflammation most doctors never run – Triglycerides plus elevated liver enzymes (AST/ALT) almost always means fatty liver, no ultrasound needed – Fibrinogen: a clotting protein made by the liver, high fibrinogen plus high insulin plus high triglycerides is a walking time bomb, especially for steroid users – CRP (C-Reactive Protein): one of the best inflammatory markers available, if it is high something serious is going on 🧬Homocysteine, the underrated killer – Homocysteine scars the inside of your arteries so plaque particles can park and stick – Now being studied as an Alzheimer's marker as well – Dr. Scott wants it at 7 or below, many people are at 9 to 50 – Fix: methylate with B6, B12, and methyl folate, simple and cheap – TRT alone will elevate homocysteine, so methylating is a must for anyone on testosterone ⚖️Retatrutide and rapid fat loss, what to watch – Losing fat very fast can back up bile flow and cause gallstones, not kidney stones – Check alkaline phosphatase and GGT before starting Reta if there is any gallbladder history – Signs of gallbladder issues: bloating, belching, pain under right rib cage, high-fat meal distress, floating stools – Floating poop is not a good sign, it means fat is not being absorbed properly – Blood sugar, triglycerides, and inflammatory markers improve dramatically and quickly on Reta 🩸Blood work timing for gear users – Best time to test: before the cycle starts, to establish your baseline – After the cycle ends: retest to confirm you returned to baseline – Mid-cycle testing will look alarming by design, be ready for that – If you do not know what different esters are, you are not ready to run gear Follow Dr. Scott Collie: Website: https://heydrscott.com/ Facebook: https://www.facebook.com/DrScottCollie/ Instagram: https://www.instagram.com/hey_dr_scott/ Join The Community: https://www.skool.com/peptideoftheweekcommunity Follow us: Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

    1h 9min
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  4. Number 4: Peptide Q&A #56 – SS-31 Deep Dive, Fertility on TRT & Building Muscle

    Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk. Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover why SS-31 has been a game changer for JD, how to properly sequence the mitochondrial stack, NAD reactions and replacements, when to come off R, building muscle at 12% body fat, fertility protocols while on TRT, and whether you really need to plan your protocols a year in advance. Chapters: 00:00 – Intro & Personal Health Updates 03:06 – SS-31 & Finding the Right Protocol 06:04 – Disneyland Trip & Kids' Sports Talk 13:48 – Warrior Makers Coaching Program Launch 18:37 – School Platform Updates & Podcast Feedback 21:58 – Q&A: Sleep, Hormones & Energy for a Busy Mum 34:15 – Q&A: Major Weight Loss & a Bad NAD Reaction 39:07 – Q&A: Peptide Storage & Condensation 41:50 – Q&A: SS-31, MOTS-C & NAD Sequencing 49:31 – Q&A: Coming Off Retatrutide's Maintenance Dose 55:22 – Q&A: TRT & Fertility Protocols 1:08:14 – Q&A: Gut Health Flare-Up & Peptide Pause 1:14:53 – Q&A: Runner Wanting Muscle Over Fat Loss 1:21:14 – Q&A: Building a Smart Annual Peptide Plan 1:29:13 – Outro & Coaching Call Details We cover: • Why JD Is Feeling the Best He Has in Years: Why higher-dose SS-31 gets the credit, why less compounds often means feeling better, and why starting with two compounds and adding slowly is the smarter approach • NAD Allergy What to Do Instead: Why reactions to NAD may come from the compound itself not just contamination, why SS-31 at five-plus megs is the closest alternative, and why blood work and hormone optimization should come first at 35 • Peptide Storage and Condensation on Vials: Why condensation on the outside of a vial does not mean moisture got inside, and why a dedicated mini fridge beats any canister solution • Mitochondrial Stack SS-31, MOTS-C and NAD Sequenced Properly: Why SS-31 plugs the holes before MOTS-C revs the engine, why quarterly month-long SS-31 cycles make sense, and why NAD can run anytime regardless • 42-Year-Old Australian Female Should You Come Off R: Why she probably doesn't need it at all, why 5-Amino-1-MQ and SLU-PP-332 are the right replacements, and why discipline is a better long-term tool than any GLP • Fertility Protocol at 33 While Trying for a Baby: Why TRT doesn't have to stop, why HCG and Kisspeptin together improve fertility odds, and why Enclomiphene is the smarter choice over standard Clomid • Building Muscle at 12% Body Fat and Running 60-70 Miles a Week: Why all that running is burning off the muscle she's trying to build, why cutting back to HIIT and lifting heavy is the real answer, and why low-dose testosterone may matter more than any IGF-1 • Total T of 420 at 43 Is It Time for TRT: Why 420 with low energy is answer enough, why TRT will change his life, and why planning protocols a full year out is overrated for most people • How to Build a Smart Annual Protocol Without Overcomplicating It: Why JD and Will plan four months at a time, why trying too many compounds at once tells you nothing, and why the gateway compounds R and BPC are always the right starting point 📌 Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results. You're a warrior. Act like one. Follow us on social media: JD's Instagram: https://www.instagram.com/jddenhamofficial/ Will's Instagram: https://www.instagram.com/williamthaas/ Join The Community: https://www.skool.com/peptideresearchinstitute/about Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/ Coaching Website: https://www.warrior-makerscoaching.com/

    1h 33min
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  5. Number 5: Peptide Q&A #57 – Peptide Math, TRT & Thick Blood, HDL on Testosterone & Hair Loss

    Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk. Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover managing high hematocrit on TRT, why HDL drops on testosterone, navigating peptide social media censorship, peptide dosing math broken down simply, hair loss and DHT blockers, and protocols for insulin resistance and PCOS. Chapters: 00:00 – Intro & School Platform Update 01:20 – Coaching Program Update & New Coaches 03:48 – Website Launch & Losing Social Media Channels 04:40 – Personal Life & Family Updates 07:13 – Upcoming Hawaii Trip 08:52 – Teaching Discipline: The Jax Story 12:23 – Q&A: Managing High Hematocrit on TRT 21:33 – Q&A: Insulin Resistance & Weight Loss 28:24 – Q&A: Peptide Dosing Math Explained 36:41 – Q&A: Navigating Social Media & Regulation 44:29 – Q&A: Low HDL on TRT 49:06 – Q&A: Adjusting Your Stack After Reaching Goal Weight 58:35 – Q&A: Hair Loss & DHT Blockers on TRT 1:07:24 – Q&A: Microplastics in Backwater Vials 1:10:14 – Q&A: PCOS, ACL Recovery & Building Muscle & Outro We cover: • High Hematocrit & Thick Blood on TRT: Why testosterone shuts off your body's governor on red blood cell production, why dehydration skews the reading, and why donating blood twice a year is the single best fix • Insulin Resistance & Slow Fat Loss in Women: Why cardio is making it worse, why 40 grams of protein right when you wake up matters, and why walking 10 minutes after every meal may do more than any peptide • Peptide Dosing Math Explained Simply: A live walkthrough of how to calculate exact milligrams per unit for GHK-CU, KPV, MOTS-C, C-Max, and "R" so nothing gets wasted • Navigating Social Media Censorship as a Peptide Educator: Why JD's YouTube got pulled for a 10-minute fasting post, why algorithms are replacing human judgment, and why School and owned platforms are the only safe play • Going Down on "R" After Reaching Goal Weight: Why 5 migs every two weeks makes no sense given the half-life, why 2-3x weekly dosing works better, and when to swap Tesamorelin for 2 IU of HGH • Low HDL on TRT — What Actually Helps: Why niacin has been proven not to work, why aromatase inhibitors make it worse, and why mono-unsaturated fats and fasting are the real levers • Hair Loss, DHT, Finasteride & Dutasteride: Why you're going to lose your hair if your family did regardless, why DHT blockers tank libido and mood, and Will's strategy of microdosing for 3 days to reset without the side effects • Plastic vs. Glass Bacteriostatic Water Vials: Why benzyl alcohol pulls microplastics from plastic vials over time and why glass is the cleaner long-term choice • 32-Year-Old Female with PCOS & ACL Tear: Why Tesamorelin-Ipa blend is the right starting point, why "R" at 500 mcg is virtually nothing, and why protein immediately after waking is non-negotiable 📌 Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results. You're a warrior. Act like one. Follow us on social media: JD's Instagram: https://www.instagram.com/jddenhamofficial/ Will's Instagram: https://www.instagram.com/williamthaas/ Join The Community: https://www.skool.com/peptideresearchinstitute/about Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/ Coaching Website: https://www.warrior-makerscoaching.com/

    1h 15min
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