Podcast Notes Playlist: Latest Episodes

Podcast Notes  Key Takeaways

• Stop counting calories. Instead:
  • Eat more nutrient-dense foods
  • Consume more protein
  • Exercise
  • Optimize your sleep
• Processed foods are designed to make you want to eat more – avoid them!
• Think twice before going vegan. Here’s why:
  • Going vegan requires more meal planning
  • Nutrient deficiencies are quite high among vegans
  • When a person eliminates eggs, milk, and meat from their diet, they’re also eliminating the most non-processed foods from their diet
• Going vegan may help lessen climate change, but…
  • “The worst thing we can do to the planet is to produce unhealthy humans” – Sal Di Stefano

Read the full notes @ podcastnotes.org



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Sal Di Stefano is one of the hosts of Mind Pump Radio and Mind Pump TV. By 19 he was managing health clubs and by 22 he owned his own gym. After 20 years as a personal trainer he has dedicated himself to bringing science and truth to the fitness industry.

“The mission of Impossible Foods is very simple. It’s to completely replace animals in the food system by 2035.”

Pat Brown

By now, most of you have heard about the Impossible Burger.

I imagine many of you have tried it.  Arguably the ‘beefiest’ plant-based patty, even the most attuned palate has trouble believing it isn’t real meat. Now ubiquitous at fine dining establishments and fast food franchises alike, it’s a global phenomenon.

Today we explore the mission behind the burger with Impossible Foods founder & CEO Pat Brown, the man responsible for upending everything you thought you knew about plant-based meat, on a mission to forge a better environmental future for all.

A world-renowned geneticist, Pat is a former Howard Hughes Medical Institute Investigator and Professor of Biochemistry at Stanford University. He is also a founder of Lyrical Foods, maker of Kite Hill artisanal nut milk-based cheeses and a founder of the Public Library of Science (PLOS), a nonprofit publisher that pioneered the open-access business model. Pat was elected to the National Academy of Sciences in 2002, and is a member of the Institute of Medicine. His numerous accolades include the American Cancer Society Medal of Honor, and the NAS Award in Molecular Biology.

Moved to action by the urgent need to redress global climate change, Pat founded Impossible Foods with one clear goal: to eliminate animal agriculture — inarguably one of the biggest contributors to planetary warming — by providing delicious, nutritious, and environmentally friendly alternatives to meat and dairy directly from plants.

The mission statement is ambitious, some would even say audacious. But his impact is already undeniable — and he’s just getting started.

Today he shares his story.

This is a broad and far-reaching conversation that covers Pat’s background and the impetus behind Impossible Foods.

We cover the company’s initial success in converting high-end chefs, the subsequent penetration of the fast food industrial complex, and the entrepreneurial difficulties of rapid growth and meeting demand at scale.

We then turn attention to Pat’s mission to redress climate change. The important need to replace food from livestock with more environmental friendly alternatives. And what is required to achieve that, while meeting the finicky palate requirements of the average consumer.

Irrespective of your opinion on plant-based meat analogues, the deleterious environmental impact of intensive animal agriculture is irrefutable. Seismic changes to our food systems are mandatory if we want to responsibly redress global climate change. And each of us has the power to promote these changes, beginning with our daily food choices.

You can watch it all go down on YouTube and as always, the audio version streams wild and free on Apple Podcasts and Spotify.

I really enjoyed this exchange. A compelling companion piece to last week’s conversation with Paul Hawken, my sit down with Beyond Meat founder and CEO Ethan Brown and my episodes with Good Food Institute founder Bruce Friedrich (RRP 286 & 402), I encourage all of you to listen with an open and appreciative mind.

Peace + Plants,

Welcome to another episode of The Tim Ferriss Show, where it is my job to sit down with world-class performers of all different types to tease out the habits, routines, favorite books, and so on that you can apply and test in your own life. This time, we have a slightly different episode.

As many of you know, I tested a "fan-supported model" earlier in the year, but I ended up reverting back to ads. It's a long story, and you can read more about it at tim.blog/podcastexperiment.

After the experiment ended, I offered an additional live Q&A with supporters as a way to say thank you. This episode is that Q&A. (If you'd like to hear the first one, you can find it here: Q&A With Tim — On Happiness, Dating, Depressive Episodes, and Much More.) 

We covered many topics: abundance mindset, balding, how I think about building a legacy, how to improve verbal tics, Lyme disease, cultivating gratitude, the grieving process, my morning routine when on a book deadline, and much more.

Please note that there were a few small glitches in the audio, but we cleaned it up, and it should be A-OK.

Please enjoy!

***

This episode is brought to you by LinkedIn Jobs. Hiring can be hard, and it and be super expensive and painful if you get it wrong. Today, with more qualified candidates than ever — but also more noise than ever — employers need a hiring solution that helps them find the right people for their businesses. LinkedIn Jobs provides just that by screening candidates with the hard and soft skills you’re looking for so you can quickly find and hire the right person.

LinkedIn can make sure your job post gets in front of people you want to hire — people with the skills, qualifications, and other insights that help LinkedIn paint a better picture of potential candidates. It’s no wonder great candidates are hired every eight seconds on LinkedIn. Find the right person meant for your business today with LinkedIn Jobs. You can pay what you want, and the first $50 is on LinkedIn. Just visit LinkedIn.com/Tim to get $50 off your first job post! Terms and conditions apply.

This episode is also brought to you by FreshBooks. I’ve been talking about FreshBooks — an all-in-one invoicing+payments+accounting solution — for years now. Many entrepreneurs, as well as the contractors and freelancers that I work with, use it all the time.

FreshBooks makes it super easy to track things like expenses, project time, and client info, and then merge it all into great-looking invoices. FreshBooks can save users up to 200 hours a year on accounting and bookkeeping tasks. Right now FreshBooks is offering my listeners a free 30-day trial, and no credit card is required. Go to FreshBooks.com/tim and enter “Tim Ferriss” in the “How did you hear about us?” section!

***

If you enjoy the podcast, would you please consider leaving a short review on Apple Podcasts/iTunes? It takes less than 60 seconds, and it really makes a difference in helping to convince hard-to-get guests. I also love reading the reviews!

For show notes and past guests, please visit tim.blog/podcast.

Sign up for Tim’s email newsletter (“5-Bullet Friday”) at tim.blog/friday.

For transcripts of episodes, go to tim.blog/transcripts.

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Podcast Notes Key Takeaways

• Eating a proper diet isn’t the only way to lower inflammation
  • You have to also examine your sleep, stress levels, the amount of time you spend on screens, etc.
• Chronic inflammation is associated with just about every health problem out there: autoimmune conditions, insulin/leptin/thyroid resistance, heart disease, cancer, neurological deterioration, brain bog, anxiety, etc.
  • “We like to separate mental health from physical health, but mental health is physical health” – Will Cole
• The chief instigators of the inflammatory cascade: grains, dairy, sugar, and high-omega-6 oils (i.e., canola oil and vegetable oil)
  • If you’re not feeling 100%, start by removing the above from your diet and see how your body responds
• Eating late at night isn’t optimal from a circadian rhythm standpoint
  • Why? – By doing so, your body is digesting/processing foods when it should be resting

Read the full notes @ podcastnotes.org



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Will Cole is a leading functional-medicine expert and consults people around the world via webcam and locally in Pittsburgh. He specializes in clinically investigating underlying factors of chronic disease and customizing health programs for thyroid issues, autoimmune conditions, hormonal dysfunctions, digestive disorders, and brain problems.

Podcast Notes Key Takeaways

• Sirtuins are a class of proteins that protect organisms from deterioration and disease by regulating gene expression (turning genes on/off)
  • Sirtuins need NAD+ to function properly
• As we get older, our NAD+ levels drop
  • By the time you’re 50, your NAD levels are about half what they were when you were 20
  • “You could argue NAD+ is the most important molecule in the body, maybe with the exception of ATP. But without either of them, you’re dead in about 30 seconds.” – David Sinclair
• NR and NMN are NAD+ precursors you can supplement with – both have been shown to raise NAD+ levels
  • You can also raise NAD+ levels with fasting and exercise 
• If sirtuins are the car, and NAD+ is the fuel, resveratrol is the accelerator pedal
  • Resveratrol also seems to improve cardiovascular health as well as stimulate autophagy pathways
• The primary cause of aging is a loss of epigenetic information (the pattern to which genes are turned on/off)

Read the full notes @ podcastnotes.org



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David A. Sinclair, PhD, is a professor in the Department of Genetics at Harvard Medical School and co-director of the Paul F. Glenn Center for the Biological Mechanisms of Aging. He is the co-founder of the journal Aging, where he serves as co-chief editor.

Dr. Sinclair's work focuses on understanding the mechanisms that drive human aging and identifying ways to slow or reverse aging's effects. In particular, he has examined the role of sirtuins in disease and aging, with special emphasis on how sirtuin activity is modulated by compounds produced by the body as well as those consumed in the diet, such as resveratrol. His work has implications for human metabolism, mitochondrial and neurological health, and cancer.

In this episode, we discuss...

• 00:17:59 - How caloric restriction, fasting, and exercise increase levels of a molecule called NAD+ and how this activates sirtuins, a family of genes involved in longevity.
• 00:21:47 - How NAD+ levels and sirtuin activities decrease with age, and how animal studies suggest that raising cellular NAD+ levels can trick the body into thinking it is younger.
• 00:23:03 - How resveratrol enhances the binding of sirtuins to NAD+ thus making sirtuins more easily activated for a longer period.
• 00:27:36 - We also discuss Steve Horvath's epigenetic aging clock, which measures DNA methylation groups, and how they may play a role in widespread gene regulation, including sirtuin genes, and how NAD+ may participate in resetting the clock.
• 00:31:54 - How the signal that resets the epigenetic clock in mice involves the Yamanaka factors -- a group of four transcription factors that can reprogram an adult cell to become a pluripotent stem cell that can form any cell type.
• 00:46:48 - How resveratrol is a xenohormetic compound and is produced when grape plants are stressed either in response to fungus or lack of water.
• 00:55:35 - How a phase 2 clinical trial involving people with Alzheimer's disease showed resveratrol improved cognitive function, improved cerebrospinal fluid amyloid beta levels, lowered markers of activated microglia, and more.
• 00:58:03 - How both nicotinamide riboside and nicotinamide mononucleotide have been shown to improve cognitive function and brain pathology in mice that have been engineered to get a disease similar to Alzheimer's disease.
• 01:06:19 - How older mice that were given nicotinamide mononucleotide experienced delayed aging in the liver, muscle, immune cells, eyes, and bones, but those that took a lower dose had improved mitochondrial function and enhanced physical performance.
• 01:01:22 - How there may be challenges in translating animal studies on nicotinamide riboside and nicotinamide mononucleotide to humans particularly due to the need to determine the dose required to promote health benefits.
• And so much more!

Click here to get this episode's show notes and transcript

Watch this episode's highlights on the FMF Clips channel

Get early access with the premium members early access podcast feed, monthly Q&A sessions, an exclusive bi-weekly science digest email, and more! Click here to get started.

Submit your raw genetic data to get the latest version of the genetic report at foundmyfitness.com/genetics.

Cal sits with investment guru Charles Schwab on the stage at the Money 2020 conference in Las Vegas to discuss the philosophies behind his success and how all of us need to look at retirement in an age when we may live 20 years longer than we expected. Plenty of takeaways from the man who’s gotten through a series of stock market bubbles while increasing the value of his company 21,000 percent over the last three decades. You read that right. Twenty-one thousand percent!

In this episode, Dr. Jud Brewer, a neuroscientist and addiction psychiatrist, discusses bad habits and how to change them.

He is the author of The Craving Mind: From Cigarettes to Smartphones to Love -- Why We Get Hooked and how We Can Break Bad Habits -- and his TED Talk on how to change a bad habit has more than 12 million views.

But...we talk about so many other things in this episode. It's a free association smorgasbord of brain stuff that will rattle your head.

::: Show Notes at YouAreNotSoSmart.com :::

SPONSORS:

• Medical Mysteries: https://www.parcast.com/medicalmysteries

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Podcast Notes Key Takeaways

• External achievements never create lasting happiness 
  • Sadly, the best way to internalize this is actually to obtain those achievements 
• We were put on Earth to live our life to the fullest – fulfill your desires, collect new experiences, and try new things (just don’t go crazy)
• Open relationships are HARD
• The pillars of a good life:
  • Take care of your body
  • Lean into discomfort
  • Cultivate and maintain a healthy community
• Quotes to ponder:
  • “Truth is love. Tell the truth and loving everyone is the same thing. You can’t love someone without telling them the truth.'”– Aubrey Marcus
    • “Our purpose here is to wake up to the truth of who we are, and all of the truth around us… If we’re all here to wake up to that truth, and we’re shielding that truth from somebody, we’re doing them a great disservice.”
  • “In a healthy relationship, instead of serving someone from your cup, you actually serve them from the overflow that fills the saucer around the cup. That way, no one’s ever drinking from their own cup of love, resources, or energy.” – Aubrey Marcus

Read the full notes @ podcastnotes.org

Aubrey Marcus is a podcaster, author and CEO.

I wanted to find out how Aubrey defines living a good life, and how he structures his world to ensure that he's pointing in the right direction... As you might be able to guess, this episode is jam packed with amazing stuff.

Aubrey is someone who contemplates the finer elements of exactly how to make his mind and body a little better every day. Enjoy this insight into the life of someone who is unashamedly working to uncover all his weaknesses and turn them into strengths.

This episode is brought to you by The Protein Works. Head to https://bit.ly/TPWChrisWillx to check out their awesome range.

Extra Stuff:

Follow Aubrey on Instagram - https://www.instagram.com/aubreymarcus

Buy Own The Day - https://amzn.to/326Ijmq

Check out Onnit - https://www.onnit.com/

Check out everything I recommend from books to products and help support the podcast at no extra cost to you by shopping through this link - https://www.amazon.co.uk/shop/modernwisdom

-

Get in touch. Join the discussion with me and other like minded listeners in the episode comments on the MW YouTube Channel or message me...

Instagram: https://www.instagram.com/chriswillx

Twitter: https://www.twitter.com/chriswillx

YouTube: https://www.youtube.com/ModernWisdomPodcast

Email: [email protected]

Podcast Notes Key Takeaways

• Systems > Goals – here’s why:
  • Committing to completing a specific goal often blinds you to other opportunities
  • With a goal, you feel as if you’re in a continuous state of failure until you achieve it
• Put yourself in situations where luck finds you
• “The best way to learn how to do something is to do it wrong”– Scott Adams
  • “If you do something wrong in front of other people and they know how you shouldn’t have done it, they’re going to tell you, and they won’t charge you for it. You can get all the free advice you want by doing bad work in public.”
• “If you’re creating art of any kind… if it doesn’t move somebody’s body, you’re not done yet”– Scott Adams
• Don’t force your creations
  • “I don’t try to create anything that I have to push. If I feel myself pushing or forcing it, I know it’s not going to work.” – Scott Adams
• Create things that you’re pulled too 
  • “If you can find an idea that pulls you, then all of the energy you’d normally have to muster on your own to put into it is unnecessary. The project actually gives you energy. It’s feeding you at the same time you’re building it.” – Scott Adams
• Turn your ego (which is usually your enemy) into a tool by dialing it up when confidence is needed, and dialing it down when it serves as a distraction
• Become aware of your blind spots by exposing yourself to concepts from a variety of different fields (psychology, history, economics, etc.)

Read the full notes @ podcastnotes.org



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Scott Adams is the creator of Dilbert, one of the most popular comic strips of all time. In addition to creating Dilbert Scott has been a Bestselling author and successful entrepreneur.

His many bestsellers include The Dilbert Principle, and How To Fail At Almost Everything And Still Win Big and his newest book Loserthink. For long time listeners of the show you know how big of a fan Sean is of Scott and on this episode they cover some his favorite topics such as Systems over goals, talent stacking and Scott’s creative process. If you want to learn how to win big in life this episode is for you!

Get the Latest from Sean right here – https://bit.ly/2RH3eaD

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Aaron Alexander, a manual therapist, movement coach and host of the Align Podcast joins us on the show today. He works with people to relieve pain, increase strength and optimize their movement. In this episode we hone in on posture: how to obtain it and how it affects so many areas of our lives for better or for worse. Tune in to learn about 12 lifestyle tips that can lead to better posture and a boost in your mood.

For the full show notes visit: https://neurohacker.com/12-lifestyle-hacks-for-better-posture (https://neurohacker.com/12-lifestyle-hacks-for-better-posture)