Podcast Notes Playlist: Latest Episodes

Another episode with Kapil Gupta laying down the Truth with a capital T

"You can systematize innovation even if you can't completely predict it." — Eric Schmidt

Eric Schmidt (@ericschmidt) is Technical Advisor and Board Member to Alphabet Inc., where he advises its leaders on technology, business and policy issues. Eric joined Google in 2001 and helped grow the company from a Silicon Valley startup to a global leader in technology. He served as Google's Chief Executive Officer from 2001-2011, and Executive Chairman 2011-2018, alongside founders Sergey Brin and Larry Page.

Eric serves on the boards of The Mayo Clinic and The Broad Institute, among others. His philanthropic efforts through The Schmidt Family Foundation focus on climate change, including support of ocean and marine life studies at sea, as well as education, specifically cutting-edge research and technology in the natural sciences and engineering. He is the founder of Schmidt Futures, which works to improve societal outcomes through the development of emerging science and technology.

He is the co-author of The New Digital Age, How Google Works, and the new book, Trillion Dollar Coach: The Leadership Playbook of Silicon Valley's Bill Campbell, which he co-authored with fellow Google leaders Jonathan Rosenberg (@jjrosenberg) and Alan Eagle (@aeaglejr).

This episode is brought to you by Inktel. Ever since I wrote The 4-Hour Workweek, I've been frequently asked about how I choose to delegate tasks. At the root of many of my decisions is a simple question: "How can I invest money to improve my quality of life?" Or "how can I spend moderate money to save significant time?"

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If you have high accountability, you're less replaceable and you can get a piece of the business.

Embrace accountability. Society will reward you with leverage.

There's no actual skill called business. Avoid business schools and magazines.

The legendary Dr. Peter Attia, MD hosts one of my favorite podcasts, The Drive, and happens to be a homie from back in my Stanford days. He dropped by Studio Z to talk about ALL the things.

Peter is a world-renowned doc and expert on human performance and longevity, although even that description doesn't scratch the surface. In this in-depth co-interview, we talked about our shared medical school experience, burnout, fixing medicine, nutrition, living longer AND better, optimizing performance, meditation, the nature of consciousness, vaccines, and a whole lot more including hilarious shit that happened to us in training, the Taint Transplant Service, Dr. Evil, and why medical culture is insane.

Links to his amazing work, the full video of our interview, and more at zdoggmd.com/incident-report-218 and peterattiamd.com

Hit me with comments and feedback at [email protected]

If you like our show, rate and subscribe on iTunes and please consider becoming a supporter on Facebook: facebook.com/becomesupporter/zdoggmd

Podcast Notes Key Takeaways

• Background and Important Stats
  • The percentage of the population (across the globe) with a food allergy is doubling every 10 years 
  • The most common food allergens are as follows:
    • Egg, milk, peanut, cashew, walnut, shrimp, wheat, and seeds
  • 50% of adults report not having their specific food allergy during childhood
    • “The fact that adults are now developing food allergies for the first time says something about the environment”
  • 10% of adults in the United States have a food allergy
  • Food allergy care costs the U.S. ~$24 billion annually
• The Importance of Epinephrine Pens
  
  • The only known treatment for an analphalactic reaction is an injectable epinephrine device
  • EVERYONE with a food allergy should carry an epinephrine pen (and probably 2, just in case the first doesn’t work or you need a second dose)
  • Just as employees in schools, restaurants and other public facilities require training in the Heimlich maneuver, how to use a fire extinguisher etc., employees should also be trained in how to use and administer an epinephrine dosing
  • Epinephrine pens should be in the rescue administration kits at all restaurants, schools, universities, and public sports events 
• The Allergic Reaction Explained
  • Immunoglobulin G (IgG) antibodies are molecules in our blood that act like a big claw – they bind to a virus, bacterial, or fungal particle and say, “Wait a minute, you’re not supposed to be here”
    • They then digests the bacteria/virus/fungal particle through a process known as endocytosis
  • There’s also IgE
    • IgE molecules basically work the same way as IgG, but confuses things like peanut/shrimp/cashew proteins (or other allergens) as the bad guy
  • What happens once IgE binds to an allergen?
    • The complex then binds to and is recognized by allergy cells (masts cell,eosinophils, or basophils) 
    • The complex then releases histamines and other inflammatory chemicals
      • This causes our blood capillaries to leak fluid, causing rapid swelling which leads to itching and redness
• What’s causing the rise in food allergies?
  • It’s thought to be a combination of environmental and other factors related to the increase in personal hygiene, more specifically the 5Ds:
    • Dirt
      • Maybe people are “too clean” and our immune systems need more exposure to certain types of bacteria
    • Dogs
      • Perhaps humans were meant to be raised in closer proximity to animals
    • Dry Skin
      • Maybe the use of detergents with washing clothes is leading to the breakdown of skin in infants more than it should be
    • VitaminD
      • It’s thought that low vitamin D levels contribute to rise in food allergies
    • Diet
      • In infancy, children should eat a diverse array of foods and be exposed to as many common allergens as possible

Read the full notes @ podcastnotes.org

The food allergy epidemic is mysterious, volatile, and growing fast. Kari Nadeau and her Stanford team are trying to halt it.

Bradley Tusk (@bradleytusk) joins Erik on this episode to talk about the intersection of politics and tech. He’s founder and CEO of Tusk Ventures and author of The Fixer: My Adventures Saving Startups From Death By Politics. He’s also a philanthropist, political strategist, and hosts his own podcast, Firewall.

Bradley has worked with Michael Bloomberg, Chuck Schumer, Uber, and many others. He shares the lessons he’s learned throughout his experience both working in politics and helping guide startups through the political and legislative processes. He explains the psyche of politicians and says that the actions of virtually every one is guided by whether it increases or decreases the chances of winning their next election.

He talks about his work with Uber and how grassroots campaigns on behalf of startups with fervid customers can sway politicians to change existing regulations that tend to benefit entrenched interests. He discusses some of the best policies that legislators can implement to benefit startups and innovation and talks specifically about some of the areas that involve the overlap of governance and tech, including charter cities, co-living, and income-share agreements.

He also talks what Silicon Valley misunderstands about politics, whether a Silicon Valley candidate could run in 2020, and how he is trying to increase voter participation through his foundation’s work on mobile and blockchain-powered voting.

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Quotable Lines From This Episode

“Every single politician I’ve ever worked with, with the exception of Mike Bloomberg, is solely motivated by the next election, and if you can do something that makes them think they’re going to lose the next election, or that you can do something to make them win the next election, they’re going to do what you want — and if you can’t do that it doesn’t matter what you want.”

“It’s especially hard with crypto and probably harder than any other sector — how do you regulate this thing that by design is meant to avoid federal currencies, avoid sovereignty, avoid nationality and is a reaction against all that?”

“The vast, vast majority of politicians, to be blunt, are desperately insecure, often self-loathing people who can’t live without the validation of holding office and running for office and they will do anything to fill that hole in their psyche.”

“In my experience, the vast majority of journalists are just curious people who are trying to figure out in any given situation. Where people get into trouble is in trying to spin them.”

“People in the Valley tend to not know what they don’t know, meaning that because they are very intelligent and because they have had success in some areas in life, they assume that that is applicable to everything they can do.”

“Politics is its totally own world, totally own world language, totally own set of norms, and just because you were a really good engineer or you figured out how to market a product that you could figure out politics too, that’s an incredibly dangerous assumption.”

“The naiveté of people in the Valley in thinking that just because they attend political fundraisers and write checks that they have some level of understanding or influence over the process. They have none.”

“There’s no one in the Valley at the moment who could plausibly be a presidential candidate in 2020.”

“You look at issues in this country like guns or immigration or healthcare or climate change, most polls show that 70% of people agree on the basic tenets of what to do about this stuff, and then there’s about 15% on either side that disagree but unfortunately right now the 15% on either side are the people that vote in primaries, so they really call the shots.”

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Today’s guest is Eugene Wei, who's spent his career working at some of the world’s best technology companies including Amazon, Hulu, and Facebook. He joined Amazon in 1997 after graduating from Stanford and it was at Amazon that he watched Jeff Bezos turn a small little internet bookstore into “The Everything Store” that were all so familiar with. After leaving Amazon, Eugene moved to New York to become a film editor before moving to Los Angeles to become a director.

That summer he joined the compa

If you understand mathematics and logic, you have the basis for understanding everything else.