• The key question to consider about work and productivity: “How do we produce stuff, and be proud and ambitious about what we are doing, but also not burn out?” 
• Pseudo-productivity places too great an emphasis on looking busy but not creating anything of value; it is busyness for the sake of busyness because measuring productivity any other way in the knowledge work sector is too difficult  
• Do not shatter your day into fragments so small that you get nothing meaningful done 
• History’s greatest knowledge workers worked very slowly 
• Doing fewer things at once will enable you to accomplish more things 
• Your results are determined by intensity in the short term and consistency in the long term 
• Never give a yes or a no in the room; not saying yes or no in the room creates psychological distance from the decision 
• “Busyness” is attractive to people because it is a goal that they can succeed at; if a person wants to be busy, they will be busy   
• Signal to others that you are very careful about your time
• “People who obsess over quality grow antibodies to busyness.” – Cal Newport 

Cal Newport is a computer science professor at Georgetown University, a productivity expert and an author.

• The Love Canal neighborhood in Niagara Falls, New York was the site of the worst environmental disaster involving chemical waste in U.S. history 
• The site was eventually filled in, and years later after selling the land to the City of Niagara for $1, housing developments and a school were built on top of it 
• In just a few years after people started living in the area, some people began developing horrible physical defects, and the rate of birth defects skyrocketed 
• Many residents who moved into the area had no idea that toxic waste was stored below them 
• In 1976, the Niagara Gazette published the first article that explained the origins of the Love Canal neighborhood, explaining the history of the Hooker Company and the toxic waste that was buried beneath the soil 
• It took several years for the issue to be acknowledged; several city-sponsored investigations took place, but the results were not shared with the local populous 
• Grassroot initiatives, led by Lois Gibbs, eventually brought national media attention to the crisis; her efforts led to $50+ million in federal and state funding to mitigate the effects of the disaster 
• A state of emergency was declared, the town was eventually shut down and flattened, and all but two families left Love Canal
• People have since moved back into the area, which is now known as Black Creek; today, some of the people living in the town remain unaware of the history of Love Canal  

A man with an unfulfilled vision left a huge gash in the ground near Niagara Falls. Then a chemical company came along and filled it with toxic waste. Then people came along and built homes and an elementary school on top of it. Then things went badly.

See omnystudio.com/listener for privacy information.

Renaissance Technologies is the best performing investment firm of all time. And yet no one at RenTec would consider themselves an “investor”, at least in any traditional sense of the word. It’d rather be more accurate to call them scientists — scientists who’ve discovered a system of math, computers and artificial intelligence that has evolved into the greatest money making machine the world has ever seen. And boy does it work: RenTec’s alchemic colossus has posted annual returns in the firm’s flagship Medallion Fund of 68% gross and 40% net over the past 34 years, while never once losing money. (For those keeping track at home, $1,000 invested in Medallion in 1988 would have compounded to $46.5B today… if you’d been allowed to keep it in.) Tune in for an incredible story of the small group of rebel mathematicians who didn’t just beat the market, but in the words of author Greg Zuckerman “solved it.”

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Note: references to Fortune in ServiceNow sponsor sections are from Fortune ©2023. Used under license.

‍Note: Acquired hosts and guests may hold assets discussed in this episode. This podcast is not investment advice, and is intended for informational and entertainment purposes only. You should do your own research and make your own independent decisions when considering any financial transactions.

• Magnesium is an essential mineral required for more than 300 metabolic reactions in the body but almost half the U.S. does not have sufficient levels (partly because of poor diet)
• One theory of aging: when we have suboptimal dietary intake, our body sacrifices the long term for the short term, producing insidious damage overtime that accelerates aging
• Stress will lower magnesium levels, even for days after stress passes
• Flaws of supplement and nutritional study design: randomized controlled trials are the gold standard for pharmaceutical interventions, but, nutritional studies need to consider individual nutrition and improve study design at the outset with consideration for baseline levels of participants if we want real answers

• Most studies are also observational so you can’t infer causality
• Micronutrients also often work in conjunction with one another – for example, magnesium is necessary for the conversion of vitamin D into its most stable form

• Confounding: magnesium is found in leafy greens, legumes, nuts, fish – and healthier foods; it may not be solely the magnesium that’s improving health

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In this solo episode, I'm taking an in-depth look at magnesium – a critical yet frequently underestimated mineral in our health. Magnesium stands tall among vital nutrients for its significant role in multiple aspects of human physiology. During this podcast, we'll delve into the widespread negative health effects caused by a lack of magnesium and discuss why increasing your magnesium intake might be key to achieving optimal health.

In this episode, I discuss:

• (00:04:27) Why the effects of magnesium are far-reaching
• (00:06:47) Why athletes need at least 10-20% more magnesium than the RDA
• (00:10:54) Why magnesium deficiency & insufficiency are common
• (00:12:19) How to determine if you're getting enough magnesium
• (00:12:23) The problem with magnesium blood tests
• (00:15:14) Magnesium supplements
• (00:18:17) Is magnesium threonate better at crossing the blood-brain barrier?
• (00:25:08) Why magnesium threonate shouldn't count toward your RDA goal
• (00:17:50) The effectiveness of epsom salt baths (see also 01:12:41)
• (00:26:04) What magnesium supplement do I take?
• (00:26:31) The effect of stress on magnesium balance
• (00:30:15) Why the energy demands of workouts affect magnesium balance
• (00:32:56) Does magnesium supplementation improve sleep?
• (00:34:04) Why trials in the field of nutrition are often misleading
• (00:37:26) Does higher magnesium intake improve cognition?
• (00:39:07) Does magnesium have a role in preventing Alzheimer's disease?
• (00:42:09) The effect of creatine on the brain (and its relationship to magnesium)
• (00:42:42) Why magnesium may prevent excitotoxicity in the brain
• (00:43:32) Magnesium's potential for managing migraines
• (00:46:41) The role of magnesium in aging
• (00:47:39) Why magnesium deficiency impairs DNA repair
• (00:49:13) Magnesium's role in cancer prevention
• (00:51:14) Why magnesium is intertwined in genomic stability
• (00:54:04) Why we shouldn't disregard observational data in nutrition
• (00:54:52) How magnesium intake affects mortality risk and cancer
• (00:57:49) Magnesium in osteoporosis prevention
• (00:59:21) Why magnesium intake in early life affects bone accretion
• (01:01:06) The effect of magnesium on vitamin D metabolism
• (01:06:36) Does magnesium treat high blood pressure?
• (01:10:12) Does magnesium help manage muscle cramps?
• (01:12:41) Is transdermal absorption of magnesium effective?
  

Watch this episode on YouTube

Show notes are available by clicking here

We finally sit down with the man himself: Nvidia Cofounder & CEO Jensen Huang. After three parts and seven+ hours of covering the company, we thought we knew everything but — unsurprisingly — Jensen knows more. A couple teasers: we learned that the company’s initial motivation to enter the datacenter business came from perhaps not where you’d think, and the roots of Nvidia’s platform strategy stretch back beyond CUDA all the way to the origin of the company.

We also got a peek into Jensen’s mindset and calculus behind “betting the company” multiple times, and his surprising feelings about whether he’d go on the founder journey again if he could rewind time. We can’t think of any better way to tie a bow on our Nvidia series (for now). Tune in!

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‍Note: Acquired hosts and guests may hold assets discussed in this episode. This podcast is not investment advice, and is intended for informational and entertainment purposes only. You should do your own research and make your own independent decisions when considering any financial transactions.