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Mike Maples Jr. is the co-founder of Floodgate (early investor in Twitter, Twitch, and Lyft) and the host of the Starting Greatness Podcast.
In this conversation, we spoke about surviving how an entrepreneur survives near-death experiences, the balance of centralization vs. decentralization, why you should seek to join a breakthrough company, and how to manage your own psychology.
Emoji to describe this episode:
This episode I am joined by Dr. Craig Heller, Professor of Biology at Stanford University and world expert on the science of temperature regulation. We discuss how the body and brain maintain temperature under different conditions and how most everyone uses the wrong approach to cool off or heat up. Dr. Heller teaches us the best ways and in doing so, explains how to offset hyperthermia and hypothermia. He also explains how we can use the precise timing and location of cooling on our body to greatly enhance endurance and weight training performance. He describes how cooling technology discovered and engineered in his laboratory has led to a tripling of anaerobic (weight training) performance and allowed endurance athletes to run further and faster, as well as to eliminate delayed onset muscle soreness. Dr. Heller explains how heat impairs muscular and mental performance, and how to cool the brain to reduce inflammation and to enhance sleep and cognition. We discuss how anyone can apply these principles for themselves, even their dogs! Our conversation includes both many practical tools and mechanistic science.
Thank you to our sponsors:
Support Research in Huberman Lab at Stanford:
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Please note that The Huberman Lab Podcast is distinct from Dr. Huberman's teaching and research roles at Stanford University School of Medicine. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Huberman Lab Podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com
In this episode of Quah (Q & A), Sal, Adam & Justin answer Pump Head questions about how men get jacked in prison if they are not eating in a calorie surplus, good glute exercises to build the butt, bench pressing with feet off the floor, and how the Mind Pump founders connected and decided to start the show.
Related Links/Products Mentioned
This episode serves as a sort of “Dopamine Masterclass”. I discuss the immensely powerful chemical that we all make in our brain and body: dopamine. I describe what it does and the neural circuits involved. I explain dopamine peaks and baselines, and the cell biology of dopamine depletion. I include 14 tools for how to control your dopamine release for sake of motivation, focus, avoiding and combating addiction and depression, and I explain why dopamine stacking with chemicals and behaviors inevitably leads to states of underwhelm and poor performance. I explain how to achieve sustained increases in baseline dopamine, compounds that injure and protect dopamine neurons including caffeine from specific sources. I describe non-prescription supplements for increasing dopamine—both their benefits and risks—and synergy of pro-dopamine supplements with those that increase acetylcholine.
Thank you to our sponsors:
Logitech Event - Rethink Education: The Biology of Learning
Support Research in Huberman Lab at Stanford:
Our Patreon page:
Supplements from Thorne:
Social:
Links:
Timestamps:
Please note that The Huberman Lab Podcast is distinct from Dr. Huberman's teaching and research roles at Stanford University School of Medicine. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Huberman Lab Podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com
Show Notes:
0:00 Bestie Guestie Balaji Srinivasan is introduced
6:01 Balaji's day in the life, Coinbase background, comparing crypto with early 2000's p2p music industry, China's lawful evil
16:09 China declares crypto transactions illegal, comparing and contrasting the US and China's future outlook
39:43 Chances of a revolution in China, predictions for the next 1-2 decades
48:37 Decentralized citizen journalism, the end of corporate journalism
58:11 Facebook's tough stretch continues: leaker might come forward with SEC, lawsuit over FTC payouts, public sentiment turning on big tech, decentralized social media
1:18:43 How decentralized media platforms would work mechanically
Follow the besties:
https://twitter.com/chamath
https://linktr.ee/calacanis
https://twitter.com/DavidSacks
https://twitter.com/friedberg
https://twitter.com/balajis
Follow the pod:
https://twitter.com/theallinpod
https://linktr.ee/allinpodcast
Intro Music Credit:
https://rb.gy/tppkzl
https://twitter.com/yung_spielburg
Intro Video Credit:
https://twitter.com/TheZachEffect
Referenced in the show:
https://www.wsj.com/articles/china-declares-bitcoin-and-other-cryptocurrency-transactions-illegal-11632479288
https://www.wsj.com/articles/xi-jinping-aims-to-rein-in-chinese-capitalism-hew-to-maos-socialist-vision-11632150725
https://www.readingthechinadream.com/
https://www.foreignaffairs.com/articles/united-states/1993-06-01/clash-civilizations
https://www.amazon.com/End-History-Last-Man/dp/0743284550
https://www.amazon.com/Kill-Chain-Defending-America-High-Tech/dp/031653353X?asin=031653353X&revisionId=&format=4&depth=1
https://www.amazon.com/Gray-Lady-Winked-Misreporting-Fabrications/dp/1736703307
https://techcrunch.com/2021/05/12/vitalik-buterin-donates-1-billion-worth-of-meme-coins-to-india-covid-relief-fund/
https://twitter.com/balajis/status/1386288771872673793?lang=en
https://twitter.com/VitalikButerin/status/1386024429629558784?s=20
https://www.amazon.com/Truth-Machine-Blockchain-Future-Everything/dp/1250114578
https://www.youtube.com/watch?v=JOWRembdPS8
https://www.washingtonpost.com/politics/2021/09/23/facebook-testify-kids-safety-lawmakers-probe-whistleblowers-revelations/
https://www.facebook.com/business/news/navigating-change-and-improving-performance-and-measurement
https://www.politico.com/news/2021/09/21/facebook-paid-billions-extra-to-the-ftc-to-spare-zuckerberg-in-data-suit-shareholders-allege-513456
https://www.sec.gov/news/press-release/2021-177
https://www.wsj.com/articles/voters-want-to-curb-the-influence-of-big-tech-companies-new-poll-shows-11632405601?st=qnnf9nvvwigp
https://medium.com/craft-ventures/masks-should-be-the-law-3f53f08709cc
https://www.politico.com/story/2017/11/01/social-media-ads-russia-wanted-americans-to-see-244423
https://balajis.com/yes-you-may-need-a-blockchain/
This episode I discuss medical research on psychedelic compounds with Dr. Matthew Johnson, Professor of Psychiatry and Behavioral Sciences at Johns Hopkins School of Medicine. We discuss the biology and medical clinical-trial uses of psilocybin, MDMA, ayahuasca, DMT, and LSD. Dr. Johnson teaches us what the clinical trials in his lab are revealing about the potential these compounds hold for the treatment of depression, addiction, trauma, eating disorders, ADHD, and other disorders of the mind. Dr. Johnson describes a typical psychedelic experiment in his laboratory, start to finish, including the conditions for optimal clinical outcomes. And he explains some of the potential hazards and common misconceptions and pitfalls related to psychedelic medicine. Dr. Johnson explains flashbacks, the heightened risks of certain people and age groups using psychedelics and the ever evolving legal and pharmaceutical industry landscape surrounding psychedelics. Dr. Johnson also explains how the scientific study of psychedelics is likely to set the trajectory of psychiatric medicine in the years to come. Dr. Johnson is among a small handful of researchers who have pioneered the clinical study of these powerful compounds. He has unprecedented insight into how they can be woven into other psychiatric treatments, changing ones sense of self and of reality.
Thank you to our sponsors:
Dr. Matthew Johnson Social Media:
Our Patreon page:
Supplements from Thorne:
Social:
Links:
Timestamps:
Please note that The Huberman Lab Podcast is distinct from Dr. Huberman's teaching and research roles at Stanford University School of Medicine. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Huberman Lab Podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com
Check out our sponsors:
Indeed: Get a FREE $75 CREDIT to upgrade your job post at indeed.com/IMPACT
Thryve: Get 70% off your at-home gut health test at trythryve.com/impact
Skillshare: Explore your creativity at skillshare.com/impacttheory for a 1 month FREE trial of Premium Membership.
Uprising: Go to uprisingfood.com/IMPACT to get $10 off the starter bundle.
Upstart: UPSTART.com/IMPACT
InsideTracker: Get 25% off their entire store at insidetracker.com/impacttheory
Whether you believe that humans and other species have evolved or you believe in a creator of living things, this episode is going to excite you or challenge you to think outside the box. Both scenarios are worthwhile, as Tom is joined by the world renowned evolutionary biologist, Richard Dawkins. Trying to fully grasp how the human mind works and what role evolution plays with our emotions, thought processes and sexual selection can be overwhelming. Tom highlights the inspiring works from Richard and discusses some complex ideas from his latest book, Books Do Furnish A Life. This is a deep dive into what evolution is, and raises the question of whether or not science, technology, and the human search for meaning and exploration has surpassed our basic evolutionary need for survival. Where does that leave humanity and what options are potential solutions worth exploring?
Order Richard Dawkins new book, Books Do Furnish A Life: https://amzn.to/39fEeSU
SHOW NOTES:
0:00 | Introduction Richard Dawkins
1:34 | How The Mind Works
7:28 | Nature of Thought & Emotion
14:01 | Emergent Properties Beyond Survival
21:13 | Lack Of Evolving Creativity
29:30 | The Great Leap Forward
30:46 | Evolution of Sexual Selection
41:25 | The Handicap Principle
45:17 | Human Sexual Selection
57:13 | Genetic Variance
1:04:07 | Finding Origin of Life
1:10:55 | Natural Selection & DNA
1:27:29 | Writing Sci-Fi & Morality
1:37:58 | Hard Problem of Consciousness
1:41:32 | Memes + Hyper Connectivity
QUOTES:
“What I tried to do in my writing career is to emphasize the rational, thoughtful side of the brain, and to not deny the existence of the emotional, but to try to foster the control of the emotions by reason.” [6:48]
“What the human mind achieves today, in the form of science in particular, technology, is utterly bewildering when you think about it in an evolutionary context. It is so far beyond what we're ever naturally selected to do.”
“The origin of life on this planet is not a highly implausible event, it’s not a very rare event...” [1:09:49]
“The idea that every particle in the universe has a minute mote of consciousness seems to me to be complete rubbish.” [1:39:17]
“It's got to be a manifestation of great complexity of interacting units. No, one of which is conscious in itself, but when you put them together, consciousness emerges from the interactions among them.” [1:40:47]
“Cultural evolution is a real phenomenon, it really looks like evolution, it really has the same progressive qualities as evolution does.” [1:42:39]
“I introduced the idea of the meme as a virus of the mind. Something that goes viral is this successful meme.” [1:45:56]
Follow Richard Dawkins:
Website: https://richarddawkins.net/
Twitter: https://twitter.com/rdfrs
Facebook: https://www.facebook.com/RichardDawkinsFoundation/
Instagram: https://www.instagram.com/richard_dawkins/
YouTube: https://www.youtube.com/user/richarddawkinsdotnet
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